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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

An Intermediate Level of BMP Signaling Directly Specifies Cranial Neural Crest Progenitor Cells in Zebrafish

Authors:
Schumacher JA, Hashiguchi M, Nguyen VH, Mullins MC
Citation:
PLoS ONE. 2011;6(11):e27403. doi:10.1371/journal.pone.0027403
Epub:
Not Epub
Abstract:
The specification of the neural crest progenitor cell (NCPC) population in the early vertebrate embryo requires an elaborate...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schumacher JA, Hashiguchi M, Nguyen VH, Mullins MC. An Intermediate Level of BMP Signaling Directly Specifies Cranial Neural Crest Progenitor Cells in Zebrafish. PLoS ONE. 2011;6(11):e27403. doi:10.1371/journal.pone.0027403.

Analysis of Pax7 expressing myogenic cells in zebrafish muscle development, injury, and models of disease

Authors:
Seger C, Hargrave M, Wang X, Chai RJ, Elworthy S, Ingham PW
Citation:
Dev Dyn. 2011;[Epub ahead of print] DOI: 10.1002/dvdy.22745
Epub:
Not Epub
Abstract:
The transcription factor Pax7 is a marker and regulator of muscle progenitors and satellite cells that contribute to the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Seger C, Hargrave M, Wang X, Chai RJ, Elworthy S, Ingham PW. Analysis of Pax7 expressing myogenic cells in zebrafish muscle development, injury, and models of disease. Dev Dyn. 2011;[Epub ahead of print] DOI: 10.1002/dvdy.22745.

Annexin IV (Xanx-4) has a functional role in the formation of pronephric tubules

Authors:
Seville RA, Nijjar S, Barnett MW, Masse K, Jones EA
Citation:
Development. 2002 Apr;129(7):1693-704.
Epub:
Not Epub
Abstract:
Vertebrate kidney organogenesis is characterised by the successive formation of the pronephros, the mesonephros and the...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Seville RA, Nijjar S, Barnett MW, Masse K, Jones EA. Annexin IV (Xanx-4) has a functional role in the formation of pronephric tubules. Development. 2002 Apr;129(7):1693-704..

Article 2: Inhibition of Neurofilament Synthesis by Morpholino Antisense Oligonucleotides Inhibits Spinal Cord Axon Regeneration

Authors:
Selzer M, Zhang G, Lin LQ
Citation:
Arch Phys Med Rehabil. 2006 Oct;87(10):e1
Epub:
Not Epub
Abstract:
Objective: To determine the role of neurofilament in central nervous system (CNS) axon regeneration. Design: Not provided....
Delivery Method:
spinal transection and retrograde transport to brain stem
Organism or Cell Type:
Lamprey
Citation Extract:
Selzer M, Zhang G, Lin LQ. Article 2: Inhibition of Neurofilament Synthesis by Morpholino Antisense Oligonucleotides Inhibits Spinal Cord Axon Regeneration. Arch Phys Med Rehabil. 2006 Oct;87(10):e1.

Aurora B regulates spindle bipolarity in meiosis in vertebrate oocytes

Authors:
Shao H, Ma C, Zhang X, Li R, Miller AL, Bement WM, Liu XJ
Citation:
Cell Cycle. 2012 Jul 15;11(14):2672-80. doi: 10.4161/cc.21016. Epub 2012 Jul 15
Epub:
Not Epub
Abstract:
Aurora B (Aur-B) plays multiple roles in mitosis, of which the best known are to ensure bi-orientation of sister chromatids by...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Shao H, Ma C, Zhang X, Li R, Miller AL, Bement WM, Liu XJ. Aurora B regulates spindle bipolarity in meiosis in vertebrate oocytes. Cell Cycle. 2012 Jul 15;11(14):2672-80. doi: 10.4161/cc.21016. Epub 2012 Jul 15.

BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly

Authors:
Seo S, Baye LM, Schulz NP, Beck JS, Zhang Q, Slusarski DC, Sheffield VC
Citation:
Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1488-93. Epub 2010 Jan 4
Epub:
Not Epub
Abstract:
Bardet-Biedl syndrome (BBS) is a human genetic disorder resulting in obesity, retinal degeneration, polydactyly, and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Seo S, Baye LM, Schulz NP, Beck JS, Zhang Q, Slusarski DC, Sheffield VC. BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly. Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1488-93. Epub 2010 Jan 4.

belladonna/(Ihx2) is required for neural patterning and midline axon guidance in the zebrafish forebrain

Authors:
Seth A, Culverwell J, Walkowicz M, Toro S, Rick JM, Neuhauss SC, Varga ZM, Karlstrom RO
Citation:
Development. 2006 Feb;133(4):725-35. Erratum in: Development. 2006 May;133(9):1856
Epub:
Not Epub
Abstract:
Some of the earliest axon pathways to form in the vertebrate forebrain are established as commissural and retinal axons cross...
Organism or Cell Type:
zebrafish
Citation Extract:
Seth A, Culverwell J, Walkowicz M, Toro S, Rick JM, Neuhauss SC, Varga ZM, Karlstrom RO. belladonna/(Ihx2) is required for neural patterning and midline axon guidance in the zebrafish forebrain. Development. 2006 Feb;133(4):725-35. Erratum in: Development. 2006 May;133(9):1856.

c-MYC antisense phosphosphorodiamidate morpholino oligomer inhibits lung metastasis in a murine tumor model

Authors:
Sekhon HS, London CA, Sekhon M, Iversen PL, Devi GR
Citation:
Lung Cancer. 2008 Jun;60(3):347-54. Epub 2007 Dec 21.
Epub:
Not Epub
Abstract:
BACKGROUND: c-MYC amplification and overexpression has been correlated with progression and chemotherapy resistance in lung...
Delivery Method:
in vivo: subcutaneous (s.c.) injection
Organism or Cell Type:
Mouse: LLC1 syngeneic tumor model
Citation Extract:
Sekhon HS, London CA, Sekhon M, Iversen PL, Devi GR. c-MYC antisense phosphosphorodiamidate morpholino oligomer inhibits lung metastasis in a murine tumor model. Lung Cancer. 2008 Jun;60(3):347-54. Epub 2007 Dec 21..

Cardiac troponin T is essential in sarcomere assembly and cardiac contractility

Authors:
Sehnert AJ, Huq A, Weinstein BM, Walker C, Fishman M, Stainier DYR.
Citation:
Nat Genet 2002 May;31(1):106-10
Epub:
Not Epub
Abstract:
Mutations of the gene (TNNT2) encoding the thin-filament contractile protein cardiac troponin T are responsible for 15% of all...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sehnert AJ, Huq A, Weinstein BM, Walker C, Fishman M, Stainier DYR.. Cardiac troponin T is essential in sarcomere assembly and cardiac contractility. Nat Genet 2002 May;31(1):106-10.

Characterization of Danio rerio Nanog and functional comparison to Xenopus Vents

Authors:
Schuff M, Siegel D, Philipp M, Bundschu K, Heymann N, Donow C, Knöchel W
Citation:
Stem Cells Dev. 2012 May 20;21(8):1225-38. doi: 10.1089/scd.2011.0285. Epub 2011 Oct 3
Epub:
Not Epub
Abstract:
Nanog is a homeodomain transcription factor associated with the acquisition of pluripotency. Genome analyses of lower and...
Delivery Method:
Microinjection and cell-free system
Organism or Cell Type:
zebrafish
Citation Extract:
Schuff M, Siegel D, Philipp M, Bundschu K, Heymann N, Donow C, Knöchel W. Characterization of Danio rerio Nanog and functional comparison to Xenopus Vents. Stem Cells Dev. 2012 May 20;21(8):1225-38. doi: 10.1089/scd.2011.0285. Epub 2011 Oct 3.

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