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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

A PHD12–Snail2 repressive complex epigenetically mediates neural crest epithelial-to-mesenchymal transition

Authors:
Strobl-Mazzulla PH, Bronner ME
Citation:
J Cell Biol. 2012;198(6):999-1010. doi: 10.1083/jcb.201203098
Epub:
Not Epub
Abstract:
Neural crest cells form within the neural tube and then undergo an epithelial to mesenchymal transition (EMT) to initiate...
Delivery Method:
Electroporation
Organism or Cell Type:
chick (Gallus gallus)
Citation Extract:
Strobl-Mazzulla PH, Bronner ME. A PHD12–Snail2 repressive complex epigenetically mediates neural crest epithelial-to-mesenchymal transition. J Cell Biol. 2012;198(6):999-1010. doi: 10.1083/jcb.201203098 .

A specificity comparison of four antisense types: morpholino, 2'-O-methyl RNA, DNA, and phosphorothioate DNA

Authors:
Stein D, Foster E, Huang SB, Weller D, Summerton J
Citation:
Antisense Nucleic Acid Drug Dev. 1997 Jun;7(3):151-7
Epub:
Not Epub
Abstract:
Cell-free translation studies were carried out to compare the efficacy and specificity of four antisense structural types: DNA...
Delivery Method:
in vitro: TNT
Citation Extract:
Stein D, Foster E, Huang SB, Weller D, Summerton J. A specificity comparison of four antisense types: morpholino, 2'-O-methyl RNA, DNA, and phosphorothioate DNA. Antisense Nucleic Acid Drug Dev. 1997 Jun;7(3):151-7.

Antagonism of microRNA Function in Zebrafish Embryos by Using Locked Nucleic Acid Enzymes (LNAzymes)

Authors:
Suryawanshi H, Lalwani MK, Ramasamy S, Rana R, Scaria V, Sivasubbu S, Maiti S
Citation:
ChemBioChem. 2012;[Epub ahead of print] doi:10.1002/cbic.201100789
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) have crucial functions in many cellular processes, such as differentiation, proliferation and apoptosis;...
Organism or Cell Type:
zebrafish
Citation Extract:
Suryawanshi H, Lalwani MK, Ramasamy S, Rana R, Scaria V, Sivasubbu S, Maiti S. Antagonism of microRNA Function in Zebrafish Embryos by Using Locked Nucleic Acid Enzymes (LNAzymes). ChemBioChem. 2012;[Epub ahead of print] doi:10.1002/cbic.201100789.

Anti-sense morpholino oligonucleotide assay shows critical involvement for NF-kappaB activation in the production of Wnt-1 protein by HepG2 cells: oncology implications

Authors:
Sun CS, Wu KT, Lee HH, Uen YH, Tian YF, Tzeng CC, Wang AH, Cheng CJ, Tsai SL
Citation:
J Biomed Sci. 2008 Sep;15(5):633-43. Epub 2008 May 7.
Epub:
Not Epub
Abstract:
The link of proto-oncogenic protein Wnt-1 production with NF-kappaB activation has been functionally demonstrated in PC12 cells...
Citation Extract:
Sun CS, Wu KT, Lee HH, Uen YH, Tian YF, Tzeng CC, Wang AH, Cheng CJ, Tsai SL. Anti-sense morpholino oligonucleotide assay shows critical involvement for NF-kappaB activation in the production of Wnt-1 protein by HepG2 cells: oncology implications. J Biomed Sci. 2008 Sep;15(5):633-43. Epub 2008 May 7..

Antihypertensive Actions of Moderate Hyperbilirubinemia: Role of Superoxide Inhibition

Authors:
Stec DE, Storm MV, Pruett BE, Gousset MU
Citation:
Am J Hypertens. 2013 Mar 12. [Epub ahead of print] doi: 10.1093/ajh/hpt038
Epub:
Not Epub
Abstract:
BACKGROUND Moderate (approximately 2-fold) increases in plasma unconjugated bilirubin levels are able to attenuate the...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice C57BL/6J
Citation Extract:
Stec DE, Storm MV, Pruett BE, Gousset MU. Antihypertensive Actions of Moderate Hyperbilirubinemia: Role of Superoxide Inhibition. Am J Hypertens. 2013 Mar 12. [Epub ahead of print] doi: 10.1093/ajh/hpt038.

Antisense modulation of RNA processing as a therapeutic approach in cancer therapy

Authors:
Spraggon L, Cartegni L
Citation:
Drug Discovery Today: Therapeutic Strategies. 2013;[Epub ahead of print] doi:10.1016/j.ddstr.2013.06.002
Epub:
Not Epub
Abstract:
Next-generation antisense technologies are re-emerging as viable and powerful approaches to the treatment of several genetic...
Citation Extract:
Spraggon L, Cartegni L. Antisense modulation of RNA processing as a therapeutic approach in cancer therapy. Drug Discovery Today: Therapeutic Strategies. 2013;[Epub ahead of print] doi:10.1016/j.ddstr.2013.06.002.

Antisense properties of morpholino oligomers

Authors:
Summerton J, Weller D
Citation:
Nucleosides Nucleotides 1997;16(7-9): 889-898
Epub:
Not Epub
Abstract:
Morpholino oligomers are third generation antisense agents designed to be cost effective, water soluble and resistant to...
Link:
http://www.tandfonline.com/doi/abs/10.1080/07328319708006105
Citation Extract:
Summerton J, Weller D. Antisense properties of morpholino oligomers. Nucleosides Nucleotides 1997;16(7-9): 889-898.

BBS10 encodes a vertebrate-specific chaperonin-like protein and is a major BBS locus

Authors:
Stoetzel C, Laurier V, Davis EE, Muller J, Rix S, Badano JL, Leitch CC, Salem N, Chouery E, Corbani S, Jalk N, Vicaire S, Sarda P, Hamel C, Lacombe D, Holder M, Odent S, Holder S, Brooks AS, Elcioglu NH, Da Silva E, Rossillion B, Sigaudy S, de Ravel TJ, Alan Lewis R, Leheup B, Verloes A, Amati-Bonneau P, Megarbane A, Poch O, Bonneau D, Beales PL, Mandel JL, Katsanis N, Dollfus H
Citation:
Nat Genet. 2006 May;38(5):521-4. Epub 2006 Apr 2.
Epub:
Not Epub
Abstract:
Bardet-Biedl syndrome (BBS) is a genetically heterogeneous ciliopathy. Although nine BBS genes have been cloned, they explain...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stoetzel C, Laurier V, Davis EE, Muller J, Rix S, Badano JL, Leitch CC, Salem N, Chouery E, Corbani S, Jalk N, Vicaire S, Sarda P, Hamel C, Lacombe D, Holder M, Odent S, Holder S, Brooks AS, Elcioglu NH, Da Silva E, Rossillion B, Sigaudy S, de Ravel TJ, Alan Lewis R, Leheup B, Verloes A, Amati-Bonneau P, Megarbane A, Poch O, Bonneau D, Beales PL, Mandel JL, Katsanis N, Dollfus H. BBS10 encodes a vertebrate-specific chaperonin-like protein and is a major BBS locus. Nat Genet. 2006 May;38(5):521-4. Epub 2006 Apr 2..

C-terminal binding proteins are essential pro-survival factors that undergo caspase-dependent downregulation during neuronal apoptosis

Authors:
Stankiewicz TR, Schroeder EK, Kelsey NA, Bouchard RJ, Linseman DA
Citation:
Mol Cell Neurosci. 2013 Jul 13. doi:pii: S1044-7431(13)00070-5. 10.1016/j.mcn.2013.07.004. [Epub ahead of print]
Epub:
Not Epub
Abstract:
C-terminal binding proteins (CtBPs) are transcriptional co-repressors that are subject to proteasome-dependent downregulation...
Citation Extract:
Stankiewicz TR, Schroeder EK, Kelsey NA, Bouchard RJ, Linseman DA. C-terminal binding proteins are essential pro-survival factors that undergo caspase-dependent downregulation during neuronal apoptosis. Mol Cell Neurosci. 2013 Jul 13. doi:pii: S1044-7431(13)00070-5. 10.1016/j.mcn.2013.07.004. [Epub ahead of print].

Ca(2+)/calmodulin-dependent protein kinase phosphatase (CaMKP) is indispensable for normal embryogenesis in zebrafish, Danio rerio

Authors:
Sueyoshi N, Nimura T, Ishida A, Taniguchi T, Yoshimura Y, Ito M, Shigeri Y, Kameshita I
Citation:
Arch Biochem Biophys. 2009 Jun 12. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Ca(2+)/calmodulin-dependent protein kinase phosphatase (CaMKP) dephosphorylates and regulates multifunctional Ca(2+)/calmodulin...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sueyoshi N, Nimura T, Ishida A, Taniguchi T, Yoshimura Y, Ito M, Shigeri Y, Kameshita I. Ca(2+)/calmodulin-dependent protein kinase phosphatase (CaMKP) is indispensable for normal embryogenesis in zebrafish, Danio rerio. Arch Biochem Biophys. 2009 Jun 12. [Epub ahead of print].

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