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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Knockdown of TGFBI/BIGH3 Corneal Dystrophy-Linked Gene Leads to Developmental Impairment in Zebrafish

Authors:
Tasinato A, Belet D, Munier FL, Neuhauss S and Schorderet DF
Citation:
Invest. Ophthalmol. Vis. Sci., May 2005; 46: 4934
Epub:
Not Epub
Abstract:
Purpose: Over 25 specific mutations in the Transforming Growth Factor beta-induced gene (TGFBI, BIGH3) are so far known to be...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tasinato A, Belet D, Munier FL, Neuhauss S and Schorderet DF. Knockdown of TGFBI/BIGH3 Corneal Dystrophy-Linked Gene Leads to Developmental Impairment in Zebrafish. Invest. Ophthalmol. Vis. Sci., May 2005; 46: 4934.

Knockdown of zebrafish Lgi1a results in abnormal development, brain defects and a seizure-like behavioral phenotype

Authors:
Teng Y, Xie X, Walker S, Rempala G, Kozlowski DJ, Mumm JS, Cowell JK
Citation:
Hum Mol Genet. 2010 Sep 6. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Epilepsy is a common disorder, typified by recurrent seizures with underlying neurological disorders or disease. Approximately...
Organism or Cell Type:
zebrafish
Citation Extract:
Teng Y, Xie X, Walker S, Rempala G, Kozlowski DJ, Mumm JS, Cowell JK. Knockdown of zebrafish Lgi1a results in abnormal development, brain defects and a seizure-like behavioral phenotype. Hum Mol Genet. 2010 Sep 6. [Epub ahead of print].

Lack of de novo phosphatidylinositol synthesis leads to endoplasmic reticulum stress and hepatic steatosis in cdipt-deficient zebrafish

Authors:
Thakur PC, Stuckenholz C, Rivera MR, Davison JM, Yao JK, Amsterdam A, Sadler KC, Bahary N
Citation:
Hepatology. 2011 Aug;54(2):452-62. doi: 10.1002/hep.24349. Epub 2011 May 2
Epub:
Not Epub
Abstract:
Hepatic steatosis is the initial stage of nonalcoholic fatty liver disease (NAFLD) and may predispose to more severe hepatic...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Thakur PC, Stuckenholz C, Rivera MR, Davison JM, Yao JK, Amsterdam A, Sadler KC, Bahary N. Lack of de novo phosphatidylinositol synthesis leads to endoplasmic reticulum stress and hepatic steatosis in cdipt-deficient zebrafish. Hepatology. 2011 Aug;54(2):452-62. doi: 10.1002/hep.24349. Epub 2011 May 2.

Lethal giant larvae 2 regulates development of the ciliated organ Kupffer’s vesicle

Authors:
Tay HG, Schulze SK, Compagnon J, Foley FC, Heisenberg C-P, Yost HJ, Abdelilah-Seyfried S, Amack JD
Citation:
Development. 2013;140:1550-1559. doi:10.1242/dev.087130
Epub:
Not Epub
Abstract:
Motile cilia perform crucial functions during embryonic development and throughout adult life. Development of organs containing...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tay HG, Schulze SK, Compagnon J, Foley FC, Heisenberg C-P, Yost HJ, Abdelilah-Seyfried S, Amack JD. Lethal giant larvae 2 regulates development of the ciliated organ Kupffer’s vesicle. Development. 2013;140:1550-1559. doi:10.1242/dev.087130 .

Loss of CHSY1, a Secreted FRINGE Enzyme, Causes Syndromic Brachydactyly in Humans via Increased NOTCH Signaling

Authors:
Tian J, Ling L, Shboul M, Lee H, O'Connor B, Merriman B, Nelson SF, Cool S, Ababneh OH, Al-Hadidy A, Masri A, Hamamy H, Reversade B
Citation:
Am J Hum Genet. 2010 Dec 1. [Epub ahead of print]
Epub:
Not Epub
Abstract:
We delineated a syndromic recessive preaxial brachydactyly with partial duplication of proximal phalanges to 16.8 Mb over 4...
Organism or Cell Type:
zebrafish
Citation Extract:
Tian J, Ling L, Shboul M, Lee H, O'Connor B, Merriman B, Nelson SF, Cool S, Ababneh OH, Al-Hadidy A, Masri A, Hamamy H, Reversade B. Loss of CHSY1, a Secreted FRINGE Enzyme, Causes Syndromic Brachydactyly in Humans via Increased NOTCH Signaling. Am J Hum Genet. 2010 Dec 1. [Epub ahead of print].

Loss of Zebrafish lgi1b Leads to Hydrocephalus and Sensitization to Pentylenetetrazol Induced Seizure-Like Behavior

Authors:
Teng Y, Xie X, Walker S, Saxena M, Kozlowski DJ, Mumm JS, Cowell JK
Citation:
PLoS ONE. 2011;6(9): e24596. doi:10.1371/journal.pone.0024596
Epub:
Not Epub
Abstract:
Mutations in the LGI1 gene predispose to a hereditary epilepsy syndrome and is the first gene associated with this disease...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Teng Y, Xie X, Walker S, Saxena M, Kozlowski DJ, Mumm JS, Cowell JK. Loss of Zebrafish lgi1b Leads to Hydrocephalus and Sensitization to Pentylenetetrazol Induced Seizure-Like Behavior. PLoS ONE. 2011;6(9): e24596. doi:10.1371/journal.pone.0024596.

Low-density lipoprotein receptor-related protein (LRP) is required for lactoferrin-enhanced collagen gel contractile activity of human fibroblasts

Authors:
Takayama Y, Takahashi H, Mizumachi K, Takezawa T
Citation:
J Biol Chem. 2003 Jun 13;278(24):22112-8. Epub 2003 Apr 01
Epub:
Not Epub
Abstract:
Fibroblasts plated on a type I collagen gel can reduce the size of the gel in a way that mimics the reorganization of the...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: WI-38 human fetal fibroblasts
Citation Extract:
Takayama Y, Takahashi H, Mizumachi K, Takezawa T. Low-density lipoprotein receptor-related protein (LRP) is required for lactoferrin-enhanced collagen gel contractile activity of human fibroblasts. J Biol Chem. 2003 Jun 13;278(24):22112-8. Epub 2003 Apr 01.

Lrp6 is required for convergent extension during Xenopus gastrulation

Authors:
Tahinci E, Thorne CA, Franklin JL, Salic A, Christian KM, Lee LA, Coffey RJ, Lee E
Citation:
Development. 2007 Nov;134(22):4095-106
Epub:
Not Epub
Abstract:
Wnt signaling regulates beta-catenin-mediated gene transcription and planar cell polarity (PCP). The Wnt co-receptor, Lrp6, is...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Tahinci E, Thorne CA, Franklin JL, Salic A, Christian KM, Lee LA, Coffey RJ, Lee E. Lrp6 is required for convergent extension during Xenopus gastrulation. Development. 2007 Nov;134(22):4095-106.

Malformation of certain brain blood vessels caused by TCDD activation of Ahr2/Arnt1 signaling in developing zebrafish

Authors:
Teraoka H, Ogawa A, Kubota A, Stegeman JJ, Peterson RE, Hiraga T
Citation:
Aquat Toxicol. 2010 May 7. [Epub ahead of print]
Epub:
Not Epub
Abstract:
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) causes various signs of toxicity in early life stages of vertebrates through...
Organism or Cell Type:
zebrafish
Citation Extract:
Teraoka H, Ogawa A, Kubota A, Stegeman JJ, Peterson RE, Hiraga T. Malformation of certain brain blood vessels caused by TCDD activation of Ahr2/Arnt1 signaling in developing zebrafish. Aquat Toxicol. 2010 May 7. [Epub ahead of print].

Manipulating gene expressions by electroporation in the developing brain of mammalian embryos

Authors:
Takahashi M, Sato K, Nomura T, Osumi N
Citation:
Differentiation. 2002 Jun;70(4-5):155-62
Epub:
Not Epub
Abstract:
One of the goals of developmental neuroscience in the post-genomic era is to clarify functions of a huge number of anonymous...
Delivery Method:
Electroporation
Organism or Cell Type:
Rat embryo, EP E11.5
Citation Extract:
Takahashi M, Sato K, Nomura T, Osumi N. Manipulating gene expressions by electroporation in the developing brain of mammalian embryos. Differentiation. 2002 Jun;70(4-5):155-62.

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