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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

In vitro efficacy of morpholino-modified antisense oligomers directed against tumor necrosis factor-alpha mRNA

Authors:
Taylor MF, Paulauskis JD, Weller DD, Kobzik L
Citation:
J Biol Chem. 1996 Jul 19;271(29):17445-52
Epub:
Not Epub
Abstract:
Chemical modification of antisense oligonucleotides to increase nuclease resistance may improve their efficacy within enzyme-...
Delivery Method:
culture: Incubation & free uptake
Organism or Cell Type:
cell culture: RAW 264.7 cells
Citation Extract:
Taylor MF, Paulauskis JD, Weller DD, Kobzik L. In vitro efficacy of morpholino-modified antisense oligomers directed against tumor necrosis factor-alpha mRNA. J Biol Chem. 1996 Jul 19;271(29):17445-52.

In vivo Electroporation of Morpholinos into the Adult Zebrafish Retina

Authors:
Thummel R, Bailey TJ, Hyde DR
Citation:
J Vis Exp. 2011;58:e3603, doi:10.3791/3603
Epub:
Not Epub
Abstract:
The adult zebrafish retina possesses a robust regenerative response. In the light-damaged retina, Müller glial cell divisions...
Delivery Method:
Electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Thummel R, Bailey TJ, Hyde DR. In vivo Electroporation of Morpholinos into the Adult Zebrafish Retina. J Vis Exp. 2011;58:e3603, doi:10.3791/3603.

Induction of cytochrome P450 1A is required for circulation failure and edema by 2,3,7,8-tetrachlorodibenzo-p-dioxin in zebrafish.

Authors:
Teraoka H, Dong W, Tsujimoto Y, Iwasa H, Endoh D, Ueno N, Stegeman JJ, Peterson RE, Hiraga T
Citation:
Biochem Biophys Res Commun 2003 May 2;304(2):223-8
Epub:
Not Epub
Abstract:
The mechanism of toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is thought to result from changes in gene expression...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Teraoka H, Dong W, Tsujimoto Y, Iwasa H, Endoh D, Ueno N, Stegeman JJ, Peterson RE, Hiraga T. Induction of cytochrome P450 1A is required for circulation failure and edema by 2,3,7,8-tetrachlorodibenzo-p-dioxin in zebrafish.. Biochem Biophys Res Commun 2003 May 2;304(2):223-8.

Inhibition of Müller glial cell division blocks regeneration of the light-damaged zebrafish retina

Authors:
Thummel R, Kassen SC, Montgomery JE, Enright JM, Hyde DR
Citation:
Dev Neurobiol. 2008 Feb 15;68(3):392-408.
Epub:
Not Epub
Abstract:
The adult zebrafish retina possesses a robust regenerative response. In the light-damaged retina, Müller glial cell divisions...
Delivery Method:
in vivo: injection then electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Thummel R, Kassen SC, Montgomery JE, Enright JM, Hyde DR. Inhibition of Müller glial cell division blocks regeneration of the light-damaged zebrafish retina. Dev Neurobiol. 2008 Feb 15;68(3):392-408..

Inhibition of neural crest migration underlies craniofacial dysmorphology and Hirschsprung's disease in Bardet-Biedl syndrome

Authors:
Tobin JL, Di Franco M, Eichers E, May-Simera H, Garcia M, Yan J, Quinlan R, Justice MJ, Hennekam RC, Briscoe J, Tada M, Mayor R, Burns AJ, Lupski JR, Hammond P, Beales PL
Citation:
Proc Natl Acad Sci U S A. 2008 May 6;105(18):6714-9. Epub 2008 Apr 28.
Epub:
Not Epub
Abstract:
Facial recognition is central to the diagnosis of many syndromes, and craniofacial patterns may reflect common etiologies. In...
Organism or Cell Type:
zebrafish
Citation Extract:
Tobin JL, Di Franco M, Eichers E, May-Simera H, Garcia M, Yan J, Quinlan R, Justice MJ, Hennekam RC, Briscoe J, Tada M, Mayor R, Burns AJ, Lupski JR, Hammond P, Beales PL. Inhibition of neural crest migration underlies craniofacial dysmorphology and Hirschsprung's disease in Bardet-Biedl syndrome. Proc Natl Acad Sci U S A. 2008 May 6;105(18):6714-9. Epub 2008 Apr 28..

Inhibition of zebrafish fin regeneration using in vivo electroporation of morpholinos against fgfr1 and msxb

Authors:
Thummel R, Bai S, Sarras MP Jr, Song P, McDermott J, Brewer J, Perry M, Zhang X, Hyde DR, Godwin AR
Citation:
Dev Dyn. 2006 Feb;235(2):336-46.
Epub:
Not Epub
Abstract:
Increased interest in using zebrafish as a model organism has led to a resurgence of fin regeneration studies. This has allowed...
Delivery Method:
microinjection and in vivo electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Thummel R, Bai S, Sarras MP Jr, Song P, McDermott J, Brewer J, Perry M, Zhang X, Hyde DR, Godwin AR. Inhibition of zebrafish fin regeneration using in vivo electroporation of morpholinos against fgfr1 and msxb. Dev Dyn. 2006 Feb;235(2):336-46..

Interplay between the tumor suppressor p53 and TGFbeta signaling shapes embryonic body axes in Xenopus

Authors:
Takebayashi-Suzuki K, Funami J, Tokumori D, Saito A, Watabe T, Miyazono K, Kanda A, Suzuki A
Citation:
Development. 2003 Sep 1;130(17):3929-3939
Epub:
Not Epub
Abstract:
The transcription factor p53 has been shown to mediate cellular responses to diverse stresses such as DNA damage. However, the...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Takebayashi-Suzuki K, Funami J, Tokumori D, Saito A, Watabe T, Miyazono K, Kanda A, Suzuki A. Interplay between the tumor suppressor p53 and TGFbeta signaling shapes embryonic body axes in Xenopus. Development. 2003 Sep 1;130(17):3929-3939.

Islet1 selectively promotes peripheral axon outgrowth in Rohon-Beard primary sensory neurons

Authors:
Tanaka H, Nojima Y, Shoji W, Sato M, Nakayama R, Ohshima T, Okamoto H
Citation:
Dev Dyn. 2010 Nov 24. [Epub ahead of print]
Epub:
Not Epub
Abstract:
We isolated a novel zebrafish mutant, lullaby (llb), and showed that the llb locus encodes the zebrafish orthologue of isl1....
Organism or Cell Type:
zebrafish
Citation Extract:
Tanaka H, Nojima Y, Shoji W, Sato M, Nakayama R, Ohshima T, Okamoto H. Islet1 selectively promotes peripheral axon outgrowth in Rohon-Beard primary sensory neurons. Dev Dyn. 2010 Nov 24. [Epub ahead of print].

Isoform switching of Cdc6 contributes to developmental cell cycle remodeling

Authors:
Tikhmyanova N, Coleman TR
Citation:
Dev Biol. 2003 Aug 15;260(2):362-75
Epub:
Not Epub
Abstract:
Xenopus laevis early development is characterized by rapid and synchronous cleavage cycles, which consist of alternating S and...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Tikhmyanova N, Coleman TR. Isoform switching of Cdc6 contributes to developmental cell cycle remodeling. Dev Biol. 2003 Aug 15;260(2):362-75.

Kermit, a frizzled interacting protein, regulates frizzled 3 signaling in neural crest development

Authors:
Tan C, Deardorff MA, Saint-Jeannet JP, Yang J, Arzoumanian A, Klein PS
Citation:
Development. 2001 Oct 1;128(19):3665-3674.
Epub:
Not Epub
Abstract:
Wnts are a family of secreted glycoproteins that are important for multiple steps in early development. Accumulating evidence...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Tan C, Deardorff MA, Saint-Jeannet JP, Yang J, Arzoumanian A, Klein PS. Kermit, a frizzled interacting protein, regulates frizzled 3 signaling in neural crest development. Development. 2001 Oct 1;128(19):3665-3674..

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