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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Essential role of beta 1,4-galactosyltransferase 2 during medaka (Oryzias latipes) gastrulation

Authors:
Tonoyama Y, Anzai D, Ikeda A, Kakuda S, Kinoshita M, Kawasaki T, Oka S
Citation:
Mech Dev. 2009 Mar 23. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Glycans are known to play important roles in vertebrate development; however, it is difficult to analyze in mammals because it...
Delivery Method:
Microinjection
Organism or Cell Type:
medaka
Citation Extract:
Tonoyama Y, Anzai D, Ikeda A, Kakuda S, Kinoshita M, Kawasaki T, Oka S. Essential role of beta 1,4-galactosyltransferase 2 during medaka (Oryzias latipes) gastrulation. Mech Dev. 2009 Mar 23. [Epub ahead of print].

Ethanol metabolism and oxidative stress are required for unfolded protein response activation and steatosis in zebrafish with alcoholic liver disease

Authors:
Tsedensodnom O, Vacaru AM, Howarth DL, Yin C, Sadler KC
Citation:
Dis Model Mech. 2013 Jul 18. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Secretory pathway dysfunction and lipid accumulation (steatosis) are the two most common responses of hepatocytes to ethanol...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tsedensodnom O, Vacaru AM, Howarth DL, Yin C, Sadler KC. Ethanol metabolism and oxidative stress are required for unfolded protein response activation and steatosis in zebrafish with alcoholic liver disease. Dis Model Mech. 2013 Jul 18. [Epub ahead of print].

Fluorescent-Based Methods for Gene Knockdown and Functional Cardiac Imaging in Zebrafish

Authors:
Umemoto N, Nishimura Y, Shimada Y, Yamanaka Y, Kishi S, Ito S, Okamori K, Nakamura Y, Kuroyanagi J, Zhang Z, Zang L, Wang Z, Nishimura N, Tanaka T
Citation:
Mol Biotechnol. 2013;55:131. doi:10.1007/s12033-013-9664-6
Epub:
Not Epub
Abstract:
A notable advantage of zebrafish as a model organism is the ease of gene knockdown using morpholino antisense oligonucleotide (...
Link:
http://link.springer.com/article/10.1007%2Fs12033-013-9664-6
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Umemoto N, Nishimura Y, Shimada Y, Yamanaka Y, Kishi S, Ito S, Okamori K, Nakamura Y, Kuroyanagi J, Zhang Z, Zang L, Wang Z, Nishimura N, Tanaka T. Fluorescent-Based Methods for Gene Knockdown and Functional Cardiac Imaging in Zebrafish. Mol Biotechnol. 2013;55:131. doi:10.1007/s12033-013-9664-6.

FoxM1-driven cell division is required for neuronal differentiation in early Xenopus embryos

Authors:
Ueno H, Nakajo N, Watanabe M, Isoda M, Sagata N
Citation:
Development. 2008 Jun;135(11):2023-30
Epub:
Not Epub
Abstract:
In vertebrate embryogenesis, neural induction is the earliest step through which the fate of embryonic ectoderm to...
Organism or Cell Type:
Xenopus
Citation Extract:
Ueno H, Nakajo N, Watanabe M, Isoda M, Sagata N. FoxM1-driven cell division is required for neuronal differentiation in early Xenopus embryos. Development. 2008 Jun;135(11):2023-30.

Function and regulation of FoxF1 during Xenopus gut development.

Authors:
Tseng HT, Shah R, Jamrich M
Citation:
Development. 2004 Aug;131(15):3637-47. Epub 2004 Jun 30.
Epub:
Not Epub
Abstract:
Development of the visceral mesoderm is a critical process in the organogenesis of the gut. Elucidation of function and...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Tseng HT, Shah R, Jamrich M. Function and regulation of FoxF1 during Xenopus gut development.. Development. 2004 Aug;131(15):3637-47. Epub 2004 Jun 30..

Functional analysis of the glucose transporters-1, -6, and -13.1 expressed by zebrafish epithelial cells

Authors:
Tseng YC, Lee JR, Lee SJ, Hwang PP
Citation:
Am J Physiol Regul Integr Comp Physiol. 2010 Dec 1. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The hexose supply and subsequent metabolism are crucial for the operations of the iono- and osmoregulatory mechanisms in fish,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tseng YC, Lee JR, Lee SJ, Hwang PP. Functional analysis of the glucose transporters-1, -6, and -13.1 expressed by zebrafish epithelial cells. Am J Physiol Regul Integr Comp Physiol. 2010 Dec 1. [Epub ahead of print].

Functional Assessment of Human Coding Mutations Affecting Skin Pigmentation Using Zebrafish

Authors:
Tsetskhladze ZR, Canfield VA, Ang KC, Wentzel SM, Reid KP, Berg AS, Johnson SL, Kawakami K, Cheng KC
Citation:
PLoS ONE. 2012;7(10): e47398. doi:10.1371/journal.pone.0047398
Epub:
Not Epub
Abstract:
A major challenge in personalized medicine is the lack of a standard way to define the functional significance of the numerous...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tsetskhladze ZR, Canfield VA, Ang KC, Wentzel SM, Reid KP, Berg AS, Johnson SL, Kawakami K, Cheng KC. Functional Assessment of Human Coding Mutations Affecting Skin Pigmentation Using Zebrafish. PLoS ONE. 2012;7(10): e47398. doi:10.1371/journal.pone.0047398.

Functional screen of zebrafish deubiquitylating enzymes by morpholino knockdown and in situ hybridization

Authors:
Tse WK, Jiang YJ
Citation:
Methods Mol Biol. 2012;815:321-31
Epub:
Not Epub
Abstract:
In order to unfold the function of genes, solely performing mRNA over-expression is not enough nowadays. Traditional protein...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tse WK, Jiang YJ. Functional screen of zebrafish deubiquitylating enzymes by morpholino knockdown and in situ hybridization. Methods Mol Biol. 2012;815:321-31.

Genome-wide loss-of-function analysis of deubiquitylating enzymes for zebrafish development

Authors:
Tse WK, Eisenhaber B, Ho SH, Ng Q, Eisenhaber F, Jiang YJ
Citation:
BMC Genomics. 2009 Dec 30;10(1):637. [Epub ahead of print]
Epub:
Not Epub
Abstract:
ABSTRACT: BACKGROUND: Deconjugation of ubiquitin and/or ubiquitin-like modified protein substrates is essential to modulate...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tse WK, Eisenhaber B, Ho SH, Ng Q, Eisenhaber F, Jiang YJ. Genome-wide loss-of-function analysis of deubiquitylating enzymes for zebrafish development. BMC Genomics. 2009 Dec 30;10(1):637. [Epub ahead of print].

Granzyme G is expressed in the two-cell stage mouse embryo and is required for the maternal-zygotic transition

Authors:
Tsai TC, Lin W, Yang SH, Cheng WT, Cheng EH, Lee MS, Chong KY, Chen CM
Citation:
BMC Dev Biol. 2010 Aug 12;10(1):88. [Epub ahead of print]
Epub:
Not Epub
Abstract:
ABSTRACT: BACKGROUND: Detailed knowledge of the molecular and cellular mechanisms that direct spatial and temporal gene...
Delivery Method:
Microinjection
Organism or Cell Type:
Mouse embryo
Citation Extract:
Tsai TC, Lin W, Yang SH, Cheng WT, Cheng EH, Lee MS, Chong KY, Chen CM. Granzyme G is expressed in the two-cell stage mouse embryo and is required for the maternal-zygotic transition. BMC Dev Biol. 2010 Aug 12;10(1):88. [Epub ahead of print].

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