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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Genetic Interaction between pku300 and fbn2b Controls Endocardial Cell Proliferation and Valve Development in Zebrafish

Authors:
Wang X, Yu Q, Wu Q, Bu Y, Chang N-N, Yan S, Zhou X-H, Zhu X, Xiong J-W
Citation:
J Cell Sci. 2013;[Epub ahead of print] doi:10.1242/jcs.116996
Epub:
Not Epub
Abstract:
Abnormal cardiac valve morphogenesis is a common cause of human congenital heart diseases. The molecular mechanisms regulating...
Organism or Cell Type:
zebrafish
Citation Extract:
Wang X, Yu Q, Wu Q, Bu Y, Chang N-N, Yan S, Zhou X-H, Zhu X, Xiong J-W. Genetic Interaction between pku300 and fbn2b Controls Endocardial Cell Proliferation and Valve Development in Zebrafish. J Cell Sci. 2013;[Epub ahead of print] doi:10.1242/jcs.116996 .

HB-EGF is necessary and sufficient for Müller glia dedifferentiation and retina regeneration

Authors:
Wan J, Ramachandran R, Goldman D
Citation:
Dev Cell. 2012 Feb 14;22(2):334-47. doi: 10.1016/j.devcel.2011.11.020
Epub:
Not Epub
Abstract:
Müller glia (MG) dedifferentiation into a cycling population of multipotent progenitors is crucial to zebrafish retina...
Delivery Method:
Retinal injection and electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Wan J, Ramachandran R, Goldman D. HB-EGF is necessary and sufficient for Müller glia dedifferentiation and retina regeneration. Dev Cell. 2012 Feb 14;22(2):334-47. doi: 10.1016/j.devcel.2011.11.020.

HIRA is essential for the development of gibel carp

Authors:
Wang M-Y, Guo Q-H, Du X-Z, Zhou L, Luo Q, Zeng Q-H, Wang J-L, Zhao H-B, Wang Y-F
Citation:
Fish Physiol Biochem. 2013;[Epub ahead of print] doi:10.1007/s10695-013-9839-x
Epub:
Not Epub
Abstract:
HIRA is one of the chaperones of histone H3.3. Mutation of Hira results in embryonic lethality in mice, suggesting a critical...
Delivery Method:
Microinjection
Organism or Cell Type:
gibel carp, Carassius auratus gibelio
Citation Extract:
Wang M-Y, Guo Q-H, Du X-Z, Zhou L, Luo Q, Zeng Q-H, Wang J-L, Zhao H-B, Wang Y-F. HIRA is essential for the development of gibel carp. Fish Physiol Biochem. 2013;[Epub ahead of print] doi:10.1007/s10695-013-9839-x.

HrzicN, a new Zic family gene of ascidians, plays essential roles in the neural tube and notochord development

Authors:
Wada S, Saiga H
Citation:
Development. 2002 Dec 15;129(24):5597-5608
Epub:
Not Epub
Abstract:
Two axial structures, a neural tube and a notochord, are key structures in the chordate body plan and in understanding the...
Delivery Method:
Microinjection
Organism or Cell Type:
Halocynthia roretzi (ascidian)
Citation Extract:
Wada S, Saiga H. HrzicN, a new Zic family gene of ascidians, plays essential roles in the neural tube and notochord development. Development. 2002 Dec 15;129(24):5597-5608.

Identification of a colonial chordate histocompatibility gene

Authors:
Voskoboynik A, Newman AM, Corey DM, Sahoo D, Pushkarev D, Neff NF, Passarelli B, Koh W, Ishizuka KJ, Palmeri KJ, Dimov IK, Keasar C, Fan HC, Mantalas GL, Sinha R, Penland L, Quake SR, Weissman IL
Citation:
Science. 2013 Jul 26;341(6144):384-7. doi: 10.1126/science.1238036
Epub:
Not Epub
Abstract:
Histocompatibility is the basis by which multicellular organisms of the same species distinguish self from nonself. Relatively...
Link:
http://science.sciencemag.org/content/341/6144/384
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Botryllus schlosseri (ascidian)
Citation Extract:
Voskoboynik A, Newman AM, Corey DM, Sahoo D, Pushkarev D, Neff NF, Passarelli B, Koh W, Ishizuka KJ, Palmeri KJ, Dimov IK, Keasar C, Fan HC, Mantalas GL, Sinha R, Penland L, Quake SR, Weissman IL. Identification of a colonial chordate histocompatibility gene. Science. 2013 Jul 26;341(6144):384-7. doi: 10.1126/science.1238036.

Identification of an INSM1 Binding Site in the Insulin Promoter: Negative Regulation of the Insulin Gene Transcription

Authors:
Wang HW, Muguira M, Liu WD, Zhang T, Chen C, Aucoin R, Breslin M, Lan M
Citation:
J Endocrinol. 2008 Jul;198(1):29-39. Epub 2008 Apr 16.
Epub:
Not Epub
Abstract:
In this study, an INSM1-binding site in the proximal promoter sequence of the insulin gene was identified. Co-transfection of...
Organism or Cell Type:
Mouse embryonic pancreas
Citation Extract:
Wang HW, Muguira M, Liu WD, Zhang T, Chen C, Aucoin R, Breslin M, Lan M. Identification of an INSM1 Binding Site in the Insulin Promoter: Negative Regulation of the Insulin Gene Transcription. J Endocrinol. 2008 Jul;198(1):29-39. Epub 2008 Apr 16..

Identification of Small Molecule Activators of BMP Signaling

Authors:
Vrijens K, Lin W, Cui J, Farmer D, Low J, Pronier E, Zeng F-Y, Shelat AA, Guy K, Taylor MR, Chen T, Roussei MF
Citation:
PLoS ONE. 2013;8(3):e59045. doi:10.1371/journal.pone.0059045
Epub:
Not Epub
Abstract:
Bone Morphogenetic Proteins (BMPs) are morphogens that play a major role in regulating development and homeostasis. Although...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Vrijens K, Lin W, Cui J, Farmer D, Low J, Pronier E, Zeng F-Y, Shelat AA, Guy K, Taylor MR, Chen T, Roussei MF. Identification of Small Molecule Activators of BMP Signaling. PLoS ONE. 2013;8(3):e59045. doi:10.1371/journal.pone.0059045.

In vitro evaluation of novel antisense oligonucleotides is predictive of in vivo exon skipping activity for Duchenne muscular dystrophy

Authors:
Wang Q, Yin H, Camelliti P, Betts C, Moulton H, Lee H, Saleh AF, Gait MJ, Wood MJ
Citation:
J Gene Med. 2010 Mar 16. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: Targeted splice modulation of pre-mRNA transcripts by antisense oligonucleotides (AOs) can correct the function of...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mdk mice, H2K mdx cells
Citation Extract:
Wang Q, Yin H, Camelliti P, Betts C, Moulton H, Lee H, Saleh AF, Gait MJ, Wood MJ. In vitro evaluation of novel antisense oligonucleotides is predictive of in vivo exon skipping activity for Duchenne muscular dystrophy. J Gene Med. 2010 Mar 16. [Epub ahead of print].

Induction of Antagonistic Soluble Decoy Receptor Tyrosine Kinases by Intronic PolyA Activation

Authors:
Vorlová S, Rocco G, LeFave CV, Jodelka FM, Hess K, Hastings ML, Henke H, Cartegni L
Citation:
Mol Cell. 2011;(43)6:927-39
Epub:
Not Epub
Abstract:
Alternative intronic polyadenylation (IPA) can generate truncated protein isoforms with significantly altered functions. Here,...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: HeLa, MDA-231 & HUVEC
Citation Extract:
Vorlová S, Rocco G, LeFave CV, Jodelka FM, Hess K, Hastings ML, Henke H, Cartegni L. Induction of Antagonistic Soluble Decoy Receptor Tyrosine Kinases by Intronic PolyA Activation. Mol Cell. 2011;(43)6:927-39.

Initiation and propagation of posterior to anterior (PA) waves in zebrafish left-right development

Authors:
Wang X, Yost HJ
Citation:
Dev Dyn. 2008 Nov 4. [Epub ahead of print]
Epub:
Not Epub
Abstract:
One of the most highly conserved steps in left-right patterning is asymmetric gene expression in lateral plate mesoderm (LPM)....
Organism or Cell Type:
zebrafish
Citation Extract:
Wang X, Yost HJ. Initiation and propagation of posterior to anterior (PA) waves in zebrafish left-right development. Dev Dyn. 2008 Nov 4. [Epub ahead of print].

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