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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Fused has evolved divergent roles in vertebrate Hedgehog signalling and motile ciliogenesis

Authors:
Wilson CW, Nguyen CT, Chen MH, Yang JH, Gacayan R, Huang J, Chen JN, Chuang PT
Citation:
Nature. 2009 Mar 22. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Hedgehog (Hh) signalling is essential for several aspects of embryogenesis. In Drosophila, Hh transduction is mediated by a...
Organism or Cell Type:
zebrafish
Citation Extract:
Wilson CW, Nguyen CT, Chen MH, Yang JH, Gacayan R, Huang J, Chen JN, Chuang PT. Fused has evolved divergent roles in vertebrate Hedgehog signalling and motile ciliogenesis. Nature. 2009 Mar 22. [Epub ahead of print].

Gene doping: the hype and the reality

Authors:
Wells DJ
Citation:
Br J Pharmacol. 2008 Jun;154(3):623-31. Epub 2008 Apr 21
Epub:
Not Epub
Abstract:
Some spectacular results from genetic manipulation of laboratory rodents and increasing developments in human gene therapy...
Delivery Method:
in vivo: injection
Organism or Cell Type:
MDX mice
Citation Extract:
Wells DJ. Gene doping: the hype and the reality. Br J Pharmacol. 2008 Jun;154(3):623-31. Epub 2008 Apr 21.

Gene-Specific Countermeasures against Ebola Virus Based on Antisense Phosphorodiamidate Morpholino Oligomers

Authors:
Warfield KL, Swenson DL, Olinger GG, Nichols DK, Pratt WD, Blouch R, Stein DA, Aman MJ, Iversen PL, Bavari S
Citation:
PLoS Pathog. 2006 Jan;2(1):e1. Epub 2006 Jan 13
Epub:
Not Epub
Abstract:
The filoviruses Marburg virus and Ebola virus (EBOV) quickly outpace host immune responses and cause hemorrhagic fever,...
Delivery Method:
Injection, cell bathing
Organism or Cell Type:
Rhesus macaque, mouse, guinea pig, Vero cells
Citation Extract:
Warfield KL, Swenson DL, Olinger GG, Nichols DK, Pratt WD, Blouch R, Stein DA, Aman MJ, Iversen PL, Bavari S. Gene-Specific Countermeasures against Ebola Virus Based on Antisense Phosphorodiamidate Morpholino Oligomers. PLoS Pathog. 2006 Jan;2(1):e1. Epub 2006 Jan 13.

Gfi1.1 regulates hematopoietic lineage differentiation during zebrafish embryogenesis

Authors:
Wei W, Wen L, Huang P, Zhang Z, Chen Y, Xiao A, Huang H, Zhu Z, Zhang B, Lin S
Citation:
Cell Res. 2008 Jun;18(6):677-85.
Epub:
Not Epub
Abstract:
Growth factor independence 1 (GFI1) is important for maturation of mammalian lymphocytes and neutrophils and maintenance of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wei W, Wen L, Huang P, Zhang Z, Chen Y, Xiao A, Huang H, Zhu Z, Zhang B, Lin S. Gfi1.1 regulates hematopoietic lineage differentiation during zebrafish embryogenesis. Cell Res. 2008 Jun;18(6):677-85..

GLUT10 is required for the development of the cardiovascular system and the notochord and connects mitochondrial function to TGFβ signaling

Authors:
Willaert A, Khatri S, Callewaert BL, Coucke PJ, Crosby SD, Lee JG, Davis EC, Shiva S, Tsang M, De Paepe A, Urban Z
Citation:
Hum Mol Genet. 2012 Mar 15;21(6):1248-59. Epub 2011 Nov 24.
Epub:
Not Epub
Abstract:
Growth factor signaling results in dramatic phenotypic changes in cells, which require commensurate alterations in cellular...
Organism or Cell Type:
zebrafish
Citation Extract:
Willaert A, Khatri S, Callewaert BL, Coucke PJ, Crosby SD, Lee JG, Davis EC, Shiva S, Tsang M, De Paepe A, Urban Z. GLUT10 is required for the development of the cardiovascular system and the notochord and connects mitochondrial function to TGFβ signaling. Hum Mol Genet. 2012 Mar 15;21(6):1248-59. Epub 2011 Nov 24..

Gsx transcription factors repress Iroquois gene expression

Authors:
Winterbottom EF, Ramsbottom SA, Isaacs HV
Citation:
Dev Dyn. 2011 Apr 29. doi: 10.1002/dvdy.22648. [Epub ahead of print]
Epub:
Not Epub
Abstract:
We have previously shown that the Gsx family homeobox gene Gsh2 is part of the regulatory network specifying dorsoventral...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Winterbottom EF, Ramsbottom SA, Isaacs HV. Gsx transcription factors repress Iroquois gene expression. Dev Dyn. 2011 Apr 29. doi: 10.1002/dvdy.22648. [Epub ahead of print].

Hedgehog and Bmp polarize hematopoietic stem cell emergence in the zebrafish dorsal aorta

Authors:
Wilkinson RN, Pouget C, Gering M, Russell AJ, Davies SG, Kimelman D, Patient R
Citation:
Dev Cell. 2009 Jun;16(6):909-16
Epub:
Not Epub
Abstract:
Hematopoietic stem cells (HSCs) are first detected in the floor of the embryonic dorsal aorta (DA), and we investigate the...
Organism or Cell Type:
zebrafish
Citation Extract:
Wilkinson RN, Pouget C, Gering M, Russell AJ, Davies SG, Kimelman D, Patient R. Hedgehog and Bmp polarize hematopoietic stem cell emergence in the zebrafish dorsal aorta. Dev Cell. 2009 Jun;16(6):909-16.

Hedgehog signaling is required for differentiation of endocardial progenitors in zebrafish

Authors:
Wong KS, Rehn K, Palencia-Desai S, Kohli V, Hunter W, Uhl JD, Rost MS, Sumanas S
Citation:
Dev Biol. 2011 Nov 12. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Endocardial cells form the inner endothelial layer of the heart tube, surrounded by the myocardium. Signaling pathways that...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wong KS, Rehn K, Palencia-Desai S, Kohli V, Hunter W, Uhl JD, Rost MS, Sumanas S. Hedgehog signaling is required for differentiation of endocardial progenitors in zebrafish. Dev Biol. 2011 Nov 12. [Epub ahead of print].

Hedgehog signaling via a calcitonin receptor-like receptor can induce arterial differentiation independently of VEGF signaling in zebrafish

Authors:
Wilkinson RN, Koudijs MJ, Patient RK, Ingham PW, Schulte-Merker S, van Eeden FJ
Citation:
Blood. 2012 Jul 12;120(2):477-88. Epub 2012 Jun 5
Epub:
Not Epub
Abstract:
Multiple signaling pathways control the specification of endothelial cells (ECs) to become arteries or veins during vertebrate...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wilkinson RN, Koudijs MJ, Patient RK, Ingham PW, Schulte-Merker S, van Eeden FJ. Hedgehog signaling via a calcitonin receptor-like receptor can induce arterial differentiation independently of VEGF signaling in zebrafish. Blood. 2012 Jul 12;120(2):477-88. Epub 2012 Jun 5.

Hoxb5b acts downstream of retinoic acid signaling in the forelimb field to restrict heart field potential in zebrafish

Authors:
Waxman JS, Keegan BR, Roberts RW, Poss KD, Yelon D
Citation:
Dev Cell. 2008 Dec;15(6):923-34
Epub:
Not Epub
Abstract:
How adjacent organ fields communicate during development is not understood. Here, we identify a mechanism in which signaling...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Waxman JS, Keegan BR, Roberts RW, Poss KD, Yelon D. Hoxb5b acts downstream of retinoic acid signaling in the forelimb field to restrict heart field potential in zebrafish. Dev Cell. 2008 Dec;15(6):923-34.

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