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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Genetic approach to evaluate specificity of small molecule drug candidates inhibiting PLK1 using zebrafish

Authors:
Zhong H, Xin S, Zhao Y, Lu J, Li S, Gong J, Yang Z, Lin S
Citation:
Mol Biosyst. 2010 Aug;6(8):1463-8. Epub 2010 May 19
Epub:
Not Epub
Abstract:
During the preclinical drug discovery process it remains a challenge to enable early elimination of candidate molecules that...
Organism or Cell Type:
zebrafish
Citation Extract:
Zhong H, Xin S, Zhao Y, Lu J, Li S, Gong J, Yang Z, Lin S. Genetic approach to evaluate specificity of small molecule drug candidates inhibiting PLK1 using zebrafish. Mol Biosyst. 2010 Aug;6(8):1463-8. Epub 2010 May 19.

Genome wide screens in yeast to identify potential binding sites and target genes of DNA-binding proteins

Authors:
Zeng J, Yan J, Wang T, Mosbrook-Davis D, Dolan KT, Christensen R, Stormo GD, Haussler D, Lathrop RH, Brachmann RK, Burgess SM
Citation:
Nucleic Acids Res. 2008 Jan;36(1):e8. Epub 2007 Dec 17
Epub:
Not Epub
Abstract:
Knowledge of all binding sites for transcriptional activators and repressors is essential for computationally aided...
Organism or Cell Type:
zebrafish
Citation Extract:
Zeng J, Yan J, Wang T, Mosbrook-Davis D, Dolan KT, Christensen R, Stormo GD, Haussler D, Lathrop RH, Brachmann RK, Burgess SM. Genome wide screens in yeast to identify potential binding sites and target genes of DNA-binding proteins. Nucleic Acids Res. 2008 Jan;36(1):e8. Epub 2007 Dec 17.

Glycated proteins stimulate reactive oxygen species production in cardiac myocytes: involvement of Nox2 (gp91phox)-containing NADPH oxidase

Authors:
Zhang M, Kho AL, Anilkumar N, Chibber R, Pagano PJ, Shah AM, Cave AC
Citation:
Circulation. 2006 Mar 7;113(9):1235-43. Epub 2006 Feb 27
Epub:
Not Epub
Abstract:
BACKGROUND: Nonenzymatic glycation that results in the production of early-glycation Amadori-modified proteins and advanced-...
Delivery Method:
Scrape Delivery
Organism or Cell Type:
cell culture: primary neonatal rat cardiomyocytes
Citation Extract:
Zhang M, Kho AL, Anilkumar N, Chibber R, Pagano PJ, Shah AM, Cave AC. Glycated proteins stimulate reactive oxygen species production in cardiac myocytes: involvement of Nox2 (gp91phox)-containing NADPH oxidase. Circulation. 2006 Mar 7;113(9):1235-43. Epub 2006 Feb 27.

GM130, a cis-Golgi protein, regulates meiotic spindle assembly and asymmetric division in mouse oocyte

Authors:
Zhang CH, Wang ZB, Quan S, Huang X, Tong JS, Ma JY, Guo L, Wei YC, Ouyang YC, Hou Y, Xing FQ, Sun QY
Citation:
Cell Cycle. 2011 Jun 1;10(11). [Epub ahead of print]
Epub:
Not Epub
Abstract:
GM130, a cis-Golgi protein, plays key roles in various mitotic events, but its function in mammalian oocyte meiosis remains...
Delivery Method:
Microinjection
Organism or Cell Type:
mouse oocytes
Citation Extract:
Zhang CH, Wang ZB, Quan S, Huang X, Tong JS, Ma JY, Guo L, Wei YC, Ouyang YC, Hou Y, Xing FQ, Sun QY. GM130, a cis-Golgi protein, regulates meiotic spindle assembly and asymmetric division in mouse oocyte. Cell Cycle. 2011 Jun 1;10(11). [Epub ahead of print].

Goldfish β-catenin cell-autonomously inhibits the expression of early neural development regulating gene vsx1

Authors:
Zhang QY, Zheng K, Ma SS, Tong Y, Luo C
Citation:
Chinese Science Bulletin. 2010;55:145-152
Epub:
Not Epub
Abstract:
β-catenin gene is essential for the formation of normal dorsal axial structure in vertebrates. Recent studies have provided...
Organism or Cell Type:
Goldfish (Carassius auratus auratus)
Citation Extract:
Zhang QY, Zheng K, Ma SS, Tong Y, Luo C. Goldfish β-catenin cell-autonomously inhibits the expression of early neural development regulating gene vsx1. Chinese Science Bulletin. 2010;55:145-152.

Grb2 Is Required for the Development of Neointima in Response to Vascular Injury

Authors:
Zhang S, Ren J, Khan MF, Cheng AM, Abendschein D, Muslin AJ
Citation:
Arterioscler Thromb Vasc Biol. 2003 Jul 3 [Epub ahead of print]
Epub:
Not Epub
Abstract:
OBJECTIVE: Neointima formation occurs in arteries in response to mechanical or chemical injury and is responsible for...
Delivery Method:
Scrape Delivery
Organism or Cell Type:
cell culture: rat aortic smooth muscle cells
Citation Extract:
Zhang S, Ren J, Khan MF, Cheng AM, Abendschein D, Muslin AJ. Grb2 Is Required for the Development of Neointima in Response to Vascular Injury. Arterioscler Thromb Vasc Biol. 2003 Jul 3 [Epub ahead of print].

Gridlock signalling pathway fashions the first embryonic artery

Authors:
Zhong TP, Childs S, Leu JP, Fishman MC
Citation:
Nature 2001 Nov 8;414(6860:216-20
Epub:
Not Epub
Abstract:
Arteries and veins are morphologically, functionally and molecularly very different, but how this distinction is established...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhong TP, Childs S, Leu JP, Fishman MC. Gridlock signalling pathway fashions the first embryonic artery. Nature 2001 Nov 8;414(6860:216-20.

Hemogenic endothelium specification and hematopoietic stem cell maintenance employ distinct Scl isoforms

Authors:
Zhen F, Lan Y, Yan B, Zhang W, Wen Z
Citation:
Development. 2013;140:3977-3985. doi:10.1242/dev.097071
Epub:
Not Epub
Abstract:
Recent studies have shown that nascent hematopoietic stem cells (HSCs) derive directly from the ventral aortic endothelium (VAE...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhen F, Lan Y, Yan B, Zhang W, Wen Z. Hemogenic endothelium specification and hematopoietic stem cell maintenance employ distinct Scl isoforms. Development. 2013;140:3977-3985. doi:10.1242/dev.097071 .

Hermes is a localized factor regulating cleavage of vegetal blastomeres in Xenopus laevis

Authors:
Zearfoss NR, Chan AP, Wu CF, Kloc M, Etkin LD
Citation:
Dev Biol. 2004 Mar 15;267(1):60-71.
Epub:
Not Epub
Abstract:
We have identified the RNA-binding protein Hermes in a screen for vegetally localized RNAs in Xenopus oocytes. The RNA...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Zearfoss NR, Chan AP, Wu CF, Kloc M, Etkin LD. Hermes is a localized factor regulating cleavage of vegetal blastomeres in Xenopus laevis. Dev Biol. 2004 Mar 15;267(1):60-71..

Hex acts with {beta}-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and Nodal

Authors:
Zamparini AL, Watts T, Gardner CE, Tomlinson SR, Johnston GI, Brickman JM
Citation:
Development. 2006 Sep;133(18):3709-22
Epub:
Not Epub
Abstract:
In Xenopus, the establishment of the anteroposterior axis involves two key signalling pathways, canonical Wnt and Nodal-related...
Organism or Cell Type:
Xenopus
Citation Extract:
Zamparini AL, Watts T, Gardner CE, Tomlinson SR, Johnston GI, Brickman JM. Hex acts with {beta}-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and Nodal. Development. 2006 Sep;133(18):3709-22.

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