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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

A chemical and genetic approach to the mode of action of fumagillin

Authors:
Zhang Y, Yeh JR, Mara A, Ju R, Hines JF, Cirone P, Griesbach HL, Schneider I, Slusarski DC, Holley SA, Crews CM
Citation:
Chem Biol. 2006 Sep;13(9):1001-9
Epub:
Not Epub
Abstract:
Previous mode of action studies identified methionine aminopeptidase 2 (MetAP-2) as the target of the antiangiogenic natural...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Y, Yeh JR, Mara A, Ju R, Hines JF, Cirone P, Griesbach HL, Schneider I, Slusarski DC, Holley SA, Crews CM. A chemical and genetic approach to the mode of action of fumagillin. Chem Biol. 2006 Sep;13(9):1001-9.

A crucial role of caldesmon in vascular development in vivo

Authors:
Zheng PP, Severijnen LA, van der Weiden M, Willemsen R, Kros JM
Citation:
Cardiovasc Res. 2008 Nov 3. [Epub ahead of print]
Epub:
Not Epub
Abstract:
AIMS: We explored the in vivo effects of knockdown of caldesmon on vascular development in zebrafish. METHODS AND RESULTS: We...
Organism or Cell Type:
zebrafish
Citation Extract:
Zheng PP, Severijnen LA, van der Weiden M, Willemsen R, Kros JM. A crucial role of caldesmon in vascular development in vivo. Cardiovasc Res. 2008 Nov 3. [Epub ahead of print].

A Reversible Plasmonic Probe Sensitive for pH in Micro/nano-spaces Based on i-motif-modulated Morpholino-AuNPs Assembly

Authors:
Zhao Y, Cao L, Ouyang J, Wang M, Wang K, Xia X
Citation:
Anal Chem. 2012;[Epub ahead of print] doi:10.1021/ac302915a
Epub:
Not Epub
Abstract:
Exploring local pH in micro/nano scale is fundamentally important for understanding micro-processes including corrosion of...
Citation Extract:
Zhao Y, Cao L, Ouyang J, Wang M, Wang K, Xia X. A Reversible Plasmonic Probe Sensitive for pH in Micro/nano-spaces Based on i-motif-modulated Morpholino-AuNPs Assembly. Anal Chem. 2012;[Epub ahead of print] doi:10.1021/ac302915a.

Agrin function associated with ocular development is a target of ethanol exposure in embryonic zebrafish

Authors:
Zhang C, Turton QM, Mackinnon S, Sulik KK, Cole GJ
Citation:
Birth Defects Res A Clin Mol Teratol. 2011 Feb 9. doi: 10.1002/bdra.20766. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: Alcohol (ethanol) is a teratogen known to affect the developing eyes, face, and brain. Among the ocular defects in...
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang C, Turton QM, Mackinnon S, Sulik KK, Cole GJ. Agrin function associated with ocular development is a target of ethanol exposure in embryonic zebrafish. Birth Defects Res A Clin Mol Teratol. 2011 Feb 9. doi: 10.1002/bdra.20766. [Epub ahead of print].

AgRP and POMC neurons are hypophysiotropic and coordinately regulate multiple endocrine axes in a larval teleost

Authors:
Zhang C, Forlano PM, Cone RD
Citation:
Cell Metab. 2012 Feb 8;15(2):256-64. doi: 10.1016/j.cmet.2011.12.014. Epub 2012 Jan 12
Epub:
Not Epub
Abstract:
Plasticity in growth and reproductive behavior is found in many vertebrate species, but is common in male teleost fish....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang C, Forlano PM, Cone RD. AgRP and POMC neurons are hypophysiotropic and coordinately regulate multiple endocrine axes in a larval teleost. Cell Metab. 2012 Feb 8;15(2):256-64. doi: 10.1016/j.cmet.2011.12.014. Epub 2012 Jan 12.

An NF-kappaB and slug regulatory loop active in early vertebrate mesoderm.

Authors:
Zhang C, Carl TF, Trudeau ED, Simmet T, Klymkowsky MW
Citation:
PLoS ONE. 2006 Dec 27;1:e106
Epub:
Not Epub
Abstract:
BACKGROUND: In both Drosophila and the mouse, the zinc finger transcription factor Snail is required for mesoderm formation;...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Zhang C, Carl TF, Trudeau ED, Simmet T, Klymkowsky MW. An NF-kappaB and slug regulatory loop active in early vertebrate mesoderm.. PLoS ONE. 2006 Dec 27;1:e106.

An otx cis-regulatory module: a key node in the sea urchin endomesoderm gene regulatory network

Authors:
Yuh CH, Dorman ER, Howard ML, Davidson EH
Citation:
Dev Biol. 2004 May 15;269(2):536-51
Epub:
Not Epub
Abstract:
An essential node in the gene regulatory network (GRN) for endomesoderm specification in the sea urchin embryo lies within the...
Delivery Method:
Microinjection
Organism or Cell Type:
Sea urchin, Strongylocentrotus purpuratus
Citation Extract:
Yuh CH, Dorman ER, Howard ML, Davidson EH. An otx cis-regulatory module: a key node in the sea urchin endomesoderm gene regulatory network. Dev Biol. 2004 May 15;269(2):536-51.

An SP1-like transcription factor Spr2 acts downstream of Fgf signaling to mediate mesoderm induction

Authors:
Zhao J, Cao Y, Zhao C, Postlethwait J, Meng A
Citation:
EMBO J. 2003 Nov 17;22(22):6078-6088
Epub:
Not Epub
Abstract:
Fgf signaling, mediated in part by the transcription factor Brachyury/Xbra/Ntl, plays important roles in mesoderm formation...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao J, Cao Y, Zhao C, Postlethwait J, Meng A. An SP1-like transcription factor Spr2 acts downstream of Fgf signaling to mediate mesoderm induction. EMBO J. 2003 Nov 17;22(22):6078-6088.

Angiomotin-Like Protein 1 Controls Endothelial Polarity and Junction Stability During Sprouting Angiogenesis

Authors:
Zheng Y, Vertuani S, Nyström S, Audebert S, Meijer I, Tegnebratt T, Borg JP, Uhlén P, Majumdar A, Holmgren L
Citation:
Circ Res. 2009 Jul 9. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Rationale: We have previously shown that angiomotin (Amot) is essential for endothelial cell migration during mouse...
Organism or Cell Type:
zebrafish
Citation Extract:
Zheng Y, Vertuani S, Nyström S, Audebert S, Meijer I, Tegnebratt T, Borg JP, Uhlén P, Majumdar A, Holmgren L. Angiomotin-Like Protein 1 Controls Endothelial Polarity and Junction Stability During Sprouting Angiogenesis. Circ Res. 2009 Jul 9. [Epub ahead of print].

Antitumorigenic potential of STAT3 alternative splicing modulation

Authors:
Zammarchi F, de Stanchina E, Bournazou E, Supakorndej T, Martires K, Riedel E, Corben AD, Bromberg JF, Cartegni L
Citation:
Proc Natl Acad Sci U S A. 2011 October 25; 108(43): 17779–17784. Published online 2011 October 17. doi: 10.1073/pnas.1108482108
Epub:
Not Epub
Abstract:
Signal transducer and activator of transcription 3 (STAT3) plays a central role in the activation of multiple oncogenic...
Link:
http://www.pnas.org/content/108/43/17779.long
Delivery Method:
Vivo-Morpholino in vivo, Morpholinos and Endo-Porter in cultures
Organism or Cell Type:
cell culture, mice
Citation Extract:
Zammarchi F, de Stanchina E, Bournazou E, Supakorndej T, Martires K, Riedel E, Corben AD, Bromberg JF, Cartegni L. Antitumorigenic potential of STAT3 alternative splicing modulation. Proc Natl Acad Sci U S A. 2011 October 25; 108(43): 17779–17784. Published online 2011 October 17. doi: 10.1073/pnas.1108482108.

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