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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Functional role of arginine during the peri-implantation period of pregnancy. I. Consequences of loss of function of arginine transporter SLC7A1 mRNA in ovine conceptus trophectoderm
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Citation:
FASEB J. 2014;[Epub ahead of print] doi:10.1096/fj.13-248757 Epub:
Yes Abstract:
Arginine, the common substrate for production of nitric oxide (NO) and polyamines in mammals, increases in the uterine lumen... Delivery Method:
Endo-Porter Organism or Cell Type:
Ovis aries oocyte Citation Extract: Wang X, Frank JW, Little DR, Dunlap KA, Satterfield MC, Burghardt RC, Hansen TR, Wu G, Bazer FW. Functional role of arginine during the peri-implantation period of pregnancy. I. Consequences of loss of function of arginine transporter SLC7A1 mRNA in ovine conceptus trophectoderm. FASEB J. 2014;[Epub ahead of print] doi:10.1096/fj.13-248757 . |
New developments in exon skipping and splice modulation therapies for neuromuscular diseases
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Citation:
Expert Opin Biol Ther. 2014 Mar 12. [Epub ahead of print] Epub:
Yes Abstract:
Introduction: Antisense oligonucleotide (AON) therapy is a form of treatment for genetic or infectious diseases using small,... Citation Extract: Touznik A, Lee JJ, Yokota T. New developments in exon skipping and splice modulation therapies for neuromuscular diseases. Expert Opin Biol Ther. 2014 Mar 12. [Epub ahead of print]. |
BMP9 mutations cause a vascular-anomaly syndrome with phenotypic overlap with hereditary hemorrhagic telangiectasia
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Citation:
Am J Hum Genet. 2013 Sep 5;93(3):530-7. doi: 10.1016/j.ajhg.2013.07.004. Epub 2013 Aug 22 Epub:
Not Epub Abstract:
Hereditary hemorrhagic telangiectasia (HHT), the most common inherited vascular disorder, is caused by mutations in genes... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wooderchak-Donahue WL, McDonald J, O'Fallon B, Upton PD, Li W, Roman BL, Young S, Plant P, Fülöp GT, Langa C, Morrell NW, Botella LM, Bernabeu C, Stevenson DA, Runo JR, Bayrak-Toydemir P. BMP9 mutations cause a vascular-anomaly syndrome with phenotypic overlap with hereditary hemorrhagic telangiectasia. Am J Hum Genet. 2013 Sep 5;93(3):530-7. doi: 10.1016/j.ajhg.2013.07.004. Epub 2013 Aug 22. |
Snx3 regulates recycling of the transferrin receptor and iron assimilation
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Citation:
Cell Metab. 2013 Mar 5;17(3):343-52. doi: 10.1016/j.cmet.2013.01.013. Epub 2013 Feb 14 Epub:
Not Epub Abstract:
Sorting of endocytic ligands and receptors is critical for diverse cellular processes. The physiological significance of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen C, Garcia-Santos D, Ishikawa Y, Seguin A, Li L, Fegan KH, Hildick-Smith GJ, Shah DI, Cooney JD, Chen W, King MJ, Yien YY, Schultz IJ, Anderson H, Dalton AJ, Freedman ML, Kingsley PD, Palis J, Hattangadi SM, Lodish HF, Ward DM, Kaplan J, Maeda T, Ponka P, Paw BH. Snx3 regulates recycling of the transferrin receptor and iron assimilation. Cell Metab. 2013 Mar 5;17(3):343-52. doi: 10.1016/j.cmet.2013.01.013. Epub 2013 Feb 14. |
What Can We Learn From Clinical Trials of Exon Skipping for DMD?
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Citation:
Molec Ther Nucleic Acids. 2014;3:e152. doi:10.1038/mtna.2014.6 Epub:
Not Epub Abstract:
No abstract - this is available as open access online. Delivery Method:
i.v. infusion Organism or Cell Type:
human Citation Extract: Lu Q-l, Cirak S, Terence Partridge T. What Can We Learn From Clinical Trials of Exon Skipping for DMD?. Molec Ther Nucleic Acids. 2014;3:e152. doi:10.1038/mtna.2014.6. |
Immunophilin FKBP52 induces Tau-P301L filamentous assembly in vitro and modulates its activity in a model of tauopathy
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Citation:
PNAS USA. 2014;[Epub ahead of print] doi:10.1073/pnas.1402645111 Epub:
Yes Abstract:
Growing evidence underlines the role attributed to abnormal forms of Tau in several neurodegenerative diseases known as... Organism or Cell Type:
zebrafish Citation Extract: Giustiniani J, Chambraud B, Sardin E, Dounane O, Guillemeau K, Nakatani H, Paquet D, Kamah A, Landrieu I, Lippens G, Baulieu E-E, Tawk M. Immunophilin FKBP52 induces Tau-P301L filamentous assembly in vitro and modulates its activity in a model of tauopathy. PNAS USA. 2014;[Epub ahead of print] doi:10.1073/pnas.1402645111. |
Multicellular Tumor Spheroids as a Model for Assessing Delivery of Oligonucleotides in Three Dimensions
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Citation:
Mol Ther Nucleic Acids. 2014;3:e153. doi:10.1038/mtna.2014.5 Epub:
Not Epub Abstract:
Oligonucleotides have shown promise in selectively manipulating gene expression in vitro, but that success has not translated... Delivery Method:
peptide-linked Organism or Cell Type:
culture: multicellular tumor spheroid Citation Extract: Carver K, Ming X, Juliano RL. Multicellular Tumor Spheroids as a Model for Assessing Delivery of Oligonucleotides in Three Dimensions. Mol Ther Nucleic Acids. 2014;3:e153. doi:10.1038/mtna.2014.5. |
Mycobacterium abscessus cording prevents phagocytosis and promotes abscess formation
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Citation:
Proc Natl Acad Sci U S A. 2014 Feb 24. [Epub ahead of print] Epub:
Yes Abstract:
Mycobacterium abscessus is a rapidly growing Mycobacterium causing a wide spectrum of clinical syndromes. It now is recognized... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bernut A, Herrmann JL, Kissa K, Dubremetz JF, Gaillard JL, Lutfalla G, Kremer L. Mycobacterium abscessus cording prevents phagocytosis and promotes abscess formation. Proc Natl Acad Sci U S A. 2014 Feb 24. [Epub ahead of print]. |
Tissue damage detection by osmotic surveillance
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Citation:
Nat Cell Biol. 2013 Sep;15(9):1123-30. doi: 10.1038/ncb2818. Epub 2013 Aug 11 Epub:
Not Epub Abstract:
How tissue damage is detected to induce inflammatory responses is unclear. Most studies have focused on damage signals released... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Enyedi B, Kala S, Nikolich-Zugich T, Niethammer P. Tissue damage detection by osmotic surveillance. Nat Cell Biol. 2013 Sep;15(9):1123-30. doi: 10.1038/ncb2818. Epub 2013 Aug 11. |
Cyclic Nrarp mRNA expression is regulated by the somitic oscillator but Nrarp protein levels do not oscillate
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Citation:
Dev Dyn. 2009 Dec;238(12):3043-55. doi: 10.1002/dvdy.22139 Epub:
Not Epub Abstract:
Somites are formed progressively from the presomitic mesoderm (PSM) in a highly regulated process according to a strict... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wright D, Ferjentsik Z, Chong SW, Qiu X, Jiang YJ, Malapert P, Pourquié O, Van Hateren N, Wilson SA, Franco C, Gerhardt H, Dale JK, Maroto M. Cyclic Nrarp mRNA expression is regulated by the somitic oscillator but Nrarp protein levels do not oscillate. Dev Dyn. 2009 Dec;238(12):3043-55. doi: 10.1002/dvdy.22139. |