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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Carbon monoxide and heme oxygenase-1 prevent intestinal inflammation in mice by promoting bacterial clearance

Authors:
Onyiah JC, Sheikh SZ, Maharshak N, Steinbach EC, Russo SM, Kobayashi T, Mackey LC, Hansen JJ, Moeser AJ, Rawls JF, Borst LB, Otterbein LE, Plevy SE
Citation:
Gastroenterology. 2013 Apr;144(4):789-98. doi: 10.1053/j.gastro.2012.12.025. Epub 2012 Dec 22
Epub:
Not Epub
Abstract:
BACKGROUND & AIMS: Heme oxygenase-1 (HO-1) and its metabolic by-product, carbon monoxide (CO), protect against intestinal...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608700/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Onyiah JC, Sheikh SZ, Maharshak N, Steinbach EC, Russo SM, Kobayashi T, Mackey LC, Hansen JJ, Moeser AJ, Rawls JF, Borst LB, Otterbein LE, Plevy SE. Carbon monoxide and heme oxygenase-1 prevent intestinal inflammation in mice by promoting bacterial clearance. Gastroenterology. 2013 Apr;144(4):789-98. doi: 10.1053/j.gastro.2012.12.025. Epub 2012 Dec 22.

α3Na+/K+-ATPase deficiency causes brain ventricle dilation and abrupt embryonic motility in zebrafish

Authors:
Doğanli C, Beck HC, Ribera AB, Oxvig C, Lykke-Hartmann K
Citation:
J Biol Chem. 2013 Mar 29;288(13):8862-74. doi: 10.1074/jbc.M112.421529. Epub 2013 Feb 11
Epub:
Not Epub
Abstract:
Na(+)/K(+)-ATPases are transmembrane ion pumps that maintain ion gradients across the basolateral plasma membrane in all animal...
Link:
http://www.jbc.org/content/288/13/8862.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Doğanli C, Beck HC, Ribera AB, Oxvig C, Lykke-Hartmann K. α3Na+/K+-ATPase deficiency causes brain ventricle dilation and abrupt embryonic motility in zebrafish. J Biol Chem. 2013 Mar 29;288(13):8862-74. doi: 10.1074/jbc.M112.421529. Epub 2013 Feb 11.

KCTD10 is critical for heart and blood vessel development of zebrafish

Authors:
Hu X, Gan S, Xie G, Li L, Chen C, Ding X, Han M, Xiang S, Zhang J
Citation:
Acta Biochim Biophys Sin. 2014;[Epub ahead of print] doi:10.1093/abbs/gmu017
Epub:
Yes
Abstract:
KCTD10 is a member of the PDIP1 family, which is highly conserved during evolution, sharing a lot of similarities among human,...
Link:
http://abbs.oxfordjournals.org/content/early/2014/04/03/abbs.gmu017.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hu X, Gan S, Xie G, Li L, Chen C, Ding X, Han M, Xiang S, Zhang J. KCTD10 is critical for heart and blood vessel development of zebrafish. Acta Biochim Biophys Sin. 2014;[Epub ahead of print] doi:10.1093/abbs/gmu017 .

ADAP2 in heart development: a candidate gene for the occurrence of cardiovascular malformations in NF1 microdeletion syndrome

Authors:
Venturin M, Carra S, Gaudenzi G, Brunelli S, Gallo GR, Moncini S, Cotelli F, Riva P
Citation:
J Med Genet. 2014;[Epub ahead of print] doi:10.1136/jmedgenet-2013-102240
Epub:
Yes
Abstract:
Background: Cardiovascular malformations have a higher incidence in patients with NF1 microdeletion syndrome compared to NF1...
Link:
http://jmg.bmj.com/content/early/2014/04/07/jmedgenet-2013-102240.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Venturin M, Carra S, Gaudenzi G, Brunelli S, Gallo GR, Moncini S, Cotelli F, Riva P. ADAP2 in heart development: a candidate gene for the occurrence of cardiovascular malformations in NF1 microdeletion syndrome. J Med Genet. 2014;[Epub ahead of print] doi:10.1136/jmedgenet-2013-102240.

The β3 subunit: a key regulator of vascular calcium channel expression (1057.10)

Authors:
Srivastava A, Song L, Kharade S, Fletcher T, Rhee S, Rusch N
Citation:
FASEB J. 2014. 28:1057.10
Epub:
Not Epub
Abstract:
The pore-forming α1C subunit of the vascular L-type Ca2+ (CaL) channels upregulates during hypertension, which may contribute...
Link:
http://www.fasebj.org/content/28/1_Supplement/1057.10.abstract
Organism or Cell Type:
cell culture: A7r5 aortic VSMC
Citation Extract:
Srivastava A, Song L, Kharade S, Fletcher T, Rhee S, Rusch N. The β3 subunit: a key regulator of vascular calcium channel expression (1057.10). FASEB J. 2014. 28:1057.10 .

Regulation of a novel isoform of Receptor Expression Enhancing Protein REEP6 in rod photoreceptors by bZIP transcription factor NRL

Authors:
Hao H, Veleri S, Sun B, Kim DS, Keeley PW, Kim JW, Yang HJ, Yadav SP, Manjunath SH, Sood R, Liu P, Reese BE, Swaroop A
Citation:
Hum Mol Genet. 2014 Apr 1. [Epub ahead of print]
Epub:
Yes
Abstract:
The Maf-family leucine zipper transcription factor NRL is essential for rod photoreceptor development and functional...
Link:
http://hmg.oxfordjournals.org/content/early/2014/04/01/hmg.ddu143.abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Hao H, Veleri S, Sun B, Kim DS, Keeley PW, Kim JW, Yang HJ, Yadav SP, Manjunath SH, Sood R, Liu P, Reese BE, Swaroop A. Regulation of a novel isoform of Receptor Expression Enhancing Protein REEP6 in rod photoreceptors by bZIP transcription factor NRL. Hum Mol Genet. 2014 Apr 1. [Epub ahead of print].

Phosphodiesterase 1A Modulates Cystogenesis in Zebrafish

Authors:
Sussman CR, Ward CJ, Leightner AC, Smith JL, Agarwal R, Harris PC, Torres VE
Citation:
J Am Soc Nephrol. 2014 Apr 3. [Epub ahead of print]
Epub:
Yes
Abstract:
Substantial evidence indicates the importance of elevated cAMP in polycystic kidney disease (PKD). Accumulation of cAMP in...
Link:
http://jasn.asnjournals.org/content/early/2014/04/02/ASN.2013040421.abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Sussman CR, Ward CJ, Leightner AC, Smith JL, Agarwal R, Harris PC, Torres VE. Phosphodiesterase 1A Modulates Cystogenesis in Zebrafish. J Am Soc Nephrol. 2014 Apr 3. [Epub ahead of print].

Sox5 Functions as a Fate Switch in Medaka Pigment Cell Development

Authors:
Nagao Y, Suzuki T, Shimizu A, Kimura T, Seki R, Adachi T, Inoue C, Omae Y, Kamei Y, Hara I, Taniguchi Y, Naruse K, Wakamatsu Y, Kelsh RN, Hibi M, Hashimoto H
Citation:
PLoS Genet. 2014);10(4):e1004246. doi:10.1371/journal.pgen.1004246
Epub:
Not Epub
Abstract:
Mechanisms generating diverse cell types from multipotent progenitors are crucial for normal development. Neural crest cells (...
Link:
http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1004246
Delivery Method:
microinjection
Organism or Cell Type:
Medaka (Oryzias latipes)
Citation Extract:
Nagao Y, Suzuki T, Shimizu A, Kimura T, Seki R, Adachi T, Inoue C, Omae Y, Kamei Y, Hara I, Taniguchi Y, Naruse K, Wakamatsu Y, Kelsh RN, Hibi M, Hashimoto H . Sox5 Functions as a Fate Switch in Medaka Pigment Cell Development. PLoS Genet. 2014);10(4):e1004246. doi:10.1371/journal.pgen.1004246.

CNNM2 Mutations Cause Impaired Brain Development and Seizures in Patients with Hypomagnesemia

Authors:
Arjona FJ, de Baaij JHF, Schlingmann KP, Lameris ALL, van Wijk E, Flik G, Regele S
Citation:
PLoS Genet. 2014;10(4):e1004267. doi:10.1371/journal.pgen.1004267
Epub:
Not Epub
Abstract:
Intellectual disability and seizures are frequently associated with hypomagnesemia and have an important genetic component....
Link:
http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1004267
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Arjona FJ, de Baaij JHF, Schlingmann KP, Lameris ALL, van Wijk E, Flik G, Regele S. CNNM2 Mutations Cause Impaired Brain Development and Seizures in Patients with Hypomagnesemia. PLoS Genet. 2014;10(4):e1004267. doi:10.1371/journal.pgen.1004267.

Knockdown of monocarboxylate transporter 8 (mct8) disturbs brain development and locomotion in zebrafish

Authors:
de Vrieze E, van de Wiel SM, Zethof J, Flik G, Klaren PH, Arjona FJ
Citation:
Endocrinology. 2014 Apr 2:en20131962. [Epub ahead of print]
Epub:
Yes
Abstract:
Allan-Herndon-Dudley syndrome (AHDS) is an inherited disorder of brain development characterized by severe psychomotor...
Link:
http://press.endocrine.org/doi/abs/10.1210/en.2013-1962
Organism or Cell Type:
zebrafish
Citation Extract:
de Vrieze E, van de Wiel SM, Zethof J, Flik G, Klaren PH, Arjona FJ. Knockdown of monocarboxylate transporter 8 (mct8) disturbs brain development and locomotion in zebrafish. Endocrinology. 2014 Apr 2:en20131962. [Epub ahead of print].

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