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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

E2a is necessary for Smad2/3-dependent transcription and the direct repression of lefty during gastrulation

Authors:
Wills AE, Baker JC
Citation:
Dev Cell. 2015 Feb 9;32(3):345-57. doi: 10.1016/j.devcel.2014.11.034
Epub:
Not Epub
Abstract:
Transcription factor complexes have varied effects on cell fate and behavior, but how this diversification of function occurs...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Wills AE, Baker JC. E2a is necessary for Smad2/3-dependent transcription and the direct repression of lefty during gastrulation. Dev Cell. 2015 Feb 9;32(3):345-57. doi: 10.1016/j.devcel.2014.11.034.

The Etv2-miR-130a Network Regulates Mesodermal Specification

Authors:
Singh BN, Kawakami Y, Akiyama R, Rasmussen TL, Garry MG, Gong W, Das S, Shi X, Koyano-Nakagawa N, Garry DJ
Citation:
Cell Rep. 2015 Nov 3;13(5):915-23. doi: 10.1016/j.celrep.2015.09.060. Epub 2015 Oct 22
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) are known to regulate critical developmental stages during embryogenesis. Here, we defined an Etv2-miR-130a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Singh BN, Kawakami Y, Akiyama R, Rasmussen TL, Garry MG, Gong W, Das S, Shi X, Koyano-Nakagawa N, Garry DJ. The Etv2-miR-130a Network Regulates Mesodermal Specification. Cell Rep. 2015 Nov 3;13(5):915-23. doi: 10.1016/j.celrep.2015.09.060. Epub 2015 Oct 22.

Four and a Half LIM Domains 1b (Fhl1b) Is Essential for Regulating the Liver versus Pancreas Fate Decision and for β-Cell Regeneration

Authors:
Xu J, Cui J, Del Campo A, Shin CH
Citation:
PLoS Genet. 2016 Feb 4;12(2):e1005831. doi: 10.1371/journal.pgen.1005831. eCollection 2016 Feb
Epub:
Not Epub
Abstract:
The liver and pancreas originate from overlapping embryonic regions, and single-cell lineage tracing in zebrafish has shown...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xu J, Cui J, Del Campo A, Shin CH. Four and a Half LIM Domains 1b (Fhl1b) Is Essential for Regulating the Liver versus Pancreas Fate Decision and for β-Cell Regeneration. PLoS Genet. 2016 Feb 4;12(2):e1005831. doi: 10.1371/journal.pgen.1005831. eCollection 2016 Feb.

Identification of cis-suppression of human disease mutations by comparative genomics

Authors:
Jordan DM, Frangakis SG, Golzio C, Cassa CA, Kurtzberg J; Task Force for Neonatal Genomics, Davis EE, Sunyaev SR, Katsanis N
Citation:
Nature. 2015 Aug 13;524(7564):225-9. doi: 10.1038/nature14497. Epub 2015 Jun 29
Epub:
Not Epub
Abstract:
Patterns of amino acid conservation have served as a tool for understanding protein evolution. The same principles have also...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jordan DM, Frangakis SG, Golzio C, Cassa CA, Kurtzberg J; Task Force for Neonatal Genomics, Davis EE, Sunyaev SR, Katsanis N. Identification of cis-suppression of human disease mutations by comparative genomics. Nature. 2015 Aug 13;524(7564):225-9. doi: 10.1038/nature14497. Epub 2015 Jun 29.

Evx1 and Evx2 specify excitatory neurotransmitter fates and suppress inhibitory fates through a Pax2-independent mechanism

Authors:
Juárez-Morales JL, Schulte CJ, Pezoa SA, Vallejo GK, Hilinski WC, England SJ, de Jager S, Lewis KE
Citation:
Neural Dev. 2016;11:5. doi:10.1186/s13064-016-0059-9
Epub:
Not Epub
Abstract:
For neurons to function correctly in neuronal circuitry they must utilize appropriate neurotransmitters. However, even though...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Juárez-Morales JL, Schulte CJ, Pezoa SA, Vallejo GK, Hilinski WC, England SJ, de Jager S, Lewis KE. Evx1 and Evx2 specify excitatory neurotransmitter fates and suppress inhibitory fates through a Pax2-independent mechanism. Neural Dev. 2016;11:5. doi:10.1186/s13064-016-0059-9.

c21orf59/kurly Controls Both Cilia Motility and Polarization

Authors:
Jaffe KM, Grimes DT, Schottenfeld-Roames J, Werner ME, Ku T-S J, Kim SK, Pelliccia JL, Morante NFC, Mitchell BJ, Burdine RD
Citation:
Cell Rep. 2016;[Epub ahead of print] doi:10.1016/j.celrep.2016.01.069
Epub:
Yes
Abstract:
Cilia are microtubule-based projections that function in the movement of extracellular fluid. This requires cilia to be: (1)...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jaffe KM, Grimes DT, Schottenfeld-Roames J, Werner ME, Ku T-S J, Kim SK, Pelliccia JL, Morante NFC, Mitchell BJ, Burdine RD. c21orf59/kurly Controls Both Cilia Motility and Polarization. Cell Rep. 2016;[Epub ahead of print] doi:10.1016/j.celrep.2016.01.069.

Reduction in E-cadherin expression fosters migration of Xenopus laevis primordial germ cells

Authors:
Baronsky T, Dzementsei A, Oelkers M, Melchert J, Pieler T, Janshoff A
Citation:
Integr Biol. 2016;[Epub ahead of print] doi:10.1039/C5IB00291E
Epub:
Yes
Abstract:
The transition from passive to active migration of primordial germ cells in Xenopus embryos correlates with a reduction in...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Baronsky T, Dzementsei A, Oelkers M, Melchert J, Pieler T, Janshoff A. Reduction in E-cadherin expression fosters migration of Xenopus laevis primordial germ cells. Integr Biol. 2016;[Epub ahead of print] doi:10.1039/C5IB00291E.

E-cadherin is required for cranial neural crest migration in xenopus laevis

Authors:
Huang C, Kratzer MC, Wedlich D, Kashef J
Citation:
Dev Biol. 2016 Feb 12. pii: S0012-1606(16)30076-8. doi: 10.1016/j.ydbio.2016.02.007. [Epub ahead of print]
Epub:
Yes
Abstract:
The cranial neural crest (CNC) is a highly motile and multipotent embryonic cell population, which migrates directionally on...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Huang C, Kratzer MC, Wedlich D, Kashef J. E-cadherin is required for cranial neural crest migration in xenopus laevis. Dev Biol. 2016 Feb 12. pii: S0012-1606(16)30076-8. doi: 10.1016/j.ydbio.2016.02.007. [Epub ahead of print].

Sf3b4-depleted Xenopus embryos: A model to study the pathogenesis of craniofacial defects in Nager syndrome

Authors:
Devotta A, Juraver-Geslin H, Gonzalez JA, Hong CS, Saint-Jeannet JP
Citation:
Dev Biol. 2016 Feb 11. pii: S0012-1606(16)30081-1. doi: 10.1016/j.ydbio.2016.02.010. [Epub ahead of print]
Epub:
Yes
Abstract:
Mandibulofacial dysostosis (MFD) is a human developmental disorder characterized by defects of the facial bones. It is the...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Devotta A, Juraver-Geslin H, Gonzalez JA, Hong CS, Saint-Jeannet JP. Sf3b4-depleted Xenopus embryos: A model to study the pathogenesis of craniofacial defects in Nager syndrome. Dev Biol. 2016 Feb 11. pii: S0012-1606(16)30081-1. doi: 10.1016/j.ydbio.2016.02.010. [Epub ahead of print].

Homologous DNA strand exchange activity of the human mitochondrial DNA helicase TWINKLE

Authors:
Sen D, Patel G, Patel SS
Citation:
Nucl Acids Res. 2016;[Epub ahead of print] doi:10.1093/nar/gkw098
Epub:
Yes
Abstract:
A crucial component of the human mitochondrial DNA replisome is the ring-shaped helicase TWINKLE—a phage T7-gene 4-like protein...
Citation Extract:
Sen D, Patel G, Patel SS. Homologous DNA strand exchange activity of the human mitochondrial DNA helicase TWINKLE. Nucl Acids Res. 2016;[Epub ahead of print] doi:10.1093/nar/gkw098.

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