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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Mutations in GDP-Mannose Pyrophosphorylase B Cause Congenital and Limb-Girdle Muscular Dystrophies Associated with Hypoglycosylation of α-Dystroglycan

Authors:
Carss KJ, Stevens E, Foley AR, Cirak S, Riemersma M, Torelli S, Hoischen A, Willer T, van Scherpenzeel M, Moore SA, Messina S, Bertini E, Bönnemann CG, Abdenur JE, Grosmann CM, Kesari A, Punetha J, Quinlivan R, Waddell LB, Young HK, Wraige E, Yau S, Brodd L, Feng L, Sewry C, Macarthur DG, North KN, Hoffman E, Stemple DL, Hurles ME, van Bokhoven H, Campbell KP, Lefeber DJ; UK10K Consortium, Lin YY, Muntoni F
Citation:
Am J Hum Genet. 2013 Jun 11. doi:pii: S0002-9297(13)00222-X. 10.1016/j.ajhg.2013.05.009. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Congenital muscular dystrophies with hypoglycosylation of α-dystroglycan (α-DG) are a heterogeneous group of disorders often...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Carss KJ, Stevens E, Foley AR, Cirak S, Riemersma M, Torelli S, Hoischen A, Willer T, van Scherpenzeel M, Moore SA, Messina S, Bertini E, Bönnemann CG, Abdenur JE, Grosmann CM, Kesari A, Punetha J, Quinlivan R, Waddell LB, Young HK, Wraige E, Yau S, Brodd L, Feng L, Sewry C, Macarthur DG, North KN, Hoffman E, Stemple DL, Hurles ME, van Bokhoven H, Campbell KP, Lefeber DJ; UK10K Consortium, Lin YY, Muntoni F. Mutations in GDP-Mannose Pyrophosphorylase B Cause Congenital and Limb-Girdle Muscular Dystrophies Associated with Hypoglycosylation of α-Dystroglycan. Am J Hum Genet. 2013 Jun 11. doi:pii: S0002-9297(13)00222-X. 10.1016/j.ajhg.2013.05.009. [Epub ahead of print].

Mutations in radial spoke head protein genes RSPH9 and RSPH4A cause primary ciliary dyskinesia with central-microtubular-pair abnormalities

Authors:
Castleman VH, Romio L, Chodhari R, Hirst RA, de Castro SC, Parker KA, Ybot-Gonzalez P, Emes RD, Wilson SW, Wallis C, Johnson CA, Herrera RJ, Rutman A, Dixon M, Shoemark A, Bush A, Hogg C, Gardiner RM, Reish O, Greene ND, O'Callaghan C, Purton S, Chung EM, Mitchison HM
Citation:
Am J Hum Genet. 2009 Feb;84(2):197-209. Epub 2009 Feb 5
Epub:
Not Epub
Abstract:
Primary ciliary dyskinesia (PCD) is a genetically heterogeneous inherited disorder arising from dysmotility of motile cilia and...
Organism or Cell Type:
zebrafish
Citation Extract:
Castleman VH, Romio L, Chodhari R, Hirst RA, de Castro SC, Parker KA, Ybot-Gonzalez P, Emes RD, Wilson SW, Wallis C, Johnson CA, Herrera RJ, Rutman A, Dixon M, Shoemark A, Bush A, Hogg C, Gardiner RM, Reish O, Greene ND, O'Callaghan C, Purton S, Chung EM, Mitchison HM. Mutations in radial spoke head protein genes RSPH9 and RSPH4A cause primary ciliary dyskinesia with central-microtubular-pair abnormalities. Am J Hum Genet. 2009 Feb;84(2):197-209. Epub 2009 Feb 5.

N-cadherin-mediated cell adhesion restricts cell proliferation in the dorsal neural tube

Authors:
Chalasani K, Brewster RM
Citation:
Mol Biol Cell. 2011 May;22(9):1505-15. Epub 2011 Mar 9
Epub:
Not Epub
Abstract:
Neural progenitors are organized as a pseudostratified epithelium held together by adherens junctions (AJs), multiprotein...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chalasani K, Brewster RM. N-cadherin-mediated cell adhesion restricts cell proliferation in the dorsal neural tube. Mol Biol Cell. 2011 May;22(9):1505-15. Epub 2011 Mar 9.

Non-canonical Wnt signaling induces ubiquitination and degradation of Syndecan4

Authors:
Carvallo L, Muñoz R, Bustos F, Escobedo N, Carrasco H, Olivares G, Larraín J
Citation:
J Biol Chem. 2010 Sep 17;285(38):29546-55. Epub 2010 Jul 16
Epub:
Not Epub
Abstract:
Dynamic regulation of cell adhesion receptors is required for proper cell migration in embryogenesis, tissue repair, and cancer...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Carvallo L, Muñoz R, Bustos F, Escobedo N, Carrasco H, Olivares G, Larraín J. Non-canonical Wnt signaling induces ubiquitination and degradation of Syndecan4. J Biol Chem. 2010 Sep 17;285(38):29546-55. Epub 2010 Jul 16.

Notch resolves mixed neural identities in the zebrafish epiphysis

Authors:
Cau E, Quillien A, Blader P
Citation:
Development. 2008 Jul;135(14):2391-401. Epub 2008 Jun 11
Epub:
Not Epub
Abstract:
Manipulation of Notch activity alters neuronal subtype identity in vertebrate neuronal lineages. Nonetheless, it remains...
Organism or Cell Type:
zebrafish
Citation Extract:
Cau E, Quillien A, Blader P. Notch resolves mixed neural identities in the zebrafish epiphysis. Development. 2008 Jul;135(14):2391-401. Epub 2008 Jun 11.

Notum Homolog Plays a Novel Role in Primary Motor Innervation

Authors:
Cantu JA, Flowers GP, Topczewski J
Citation:
J Neurosci. 2013 Jan 30;33(5):2177-87. doi: 10.1523/JNEUROSCI.3694-12.2013.
Epub:
Not Epub
Abstract:
To form complex neuronal networks, growth cones use intermediate targets as guideposts on the path to more distant targets. In...
Organism or Cell Type:
zebrafish
Citation Extract:
Cantu JA, Flowers GP, Topczewski J. Notum Homolog Plays a Novel Role in Primary Motor Innervation. J Neurosci. 2013 Jan 30;33(5):2177-87. doi: 10.1523/JNEUROSCI.3694-12.2013..

Oct25 represses transcription of nodal/activin target genes by interaction with signal transducers during Xenopus gastrulation

Authors:
Cao Y, Siegel D, Oswald F, Knöchel W
Citation:
J Biol Chem. 2008 Dec 5;283(49):34168-77. Epub 2008 Oct 15
Epub:
Not Epub
Abstract:
The balance between differentiation signals and signals maintaining the undifferentiated state of embryonic cells ensures...
Organism or Cell Type:
Xenopus
Citation Extract:
Cao Y, Siegel D, Oswald F, Knöchel W. Oct25 represses transcription of nodal/activin target genes by interaction with signal transducers during Xenopus gastrulation. J Biol Chem. 2008 Dec 5;283(49):34168-77. Epub 2008 Oct 15.

OTX2 mutations contribute to the otocephaly-dysgnathia complex

Authors:
Chassaing N, Sorrentino S, Davis EE, Martin-Coignard D, Iacovelli A, Paznekas W, Webb BD, Faye-Petersen O, Encha-Razavi F, Lequeux L, Vigouroux A, Yesilyurt A, Boyadjiev SA, Kayserili H, Loget P, Carles D, Sergi C, Puvabanditsin S, Chen CP, Etchevers HC, Katsanis N, Mercer CL, Calvas P, Jabs EW
Citation:
J Med Genet. 2012;[Epub ahead of print] doi:10.1136/jmedgenet-2012-100892
Epub:
Not Epub
Abstract:
Background Otocephaly or dysgnathia complex is characterised by mandibular hypoplasia/agenesis, ear anomalies, microstomia,...
Organism or Cell Type:
zebrafish
Citation Extract:
Chassaing N, Sorrentino S, Davis EE, Martin-Coignard D, Iacovelli A, Paznekas W, Webb BD, Faye-Petersen O, Encha-Razavi F, Lequeux L, Vigouroux A, Yesilyurt A, Boyadjiev SA, Kayserili H, Loget P, Carles D, Sergi C, Puvabanditsin S, Chen CP, Etchevers HC, Katsanis N, Mercer CL, Calvas P, Jabs EW. OTX2 mutations contribute to the otocephaly-dysgnathia complex. J Med Genet. 2012;[Epub ahead of print] doi:10.1136/jmedgenet-2012-100892 .

Patterning a spiralian embryo: A segregated RNA for a Tis11 ortholog is required in the 3a and 3b cells of the Ilyanassa embryo

Authors:
Chan XY, Lambert JD
Citation:
Dev Biol. 2010 Oct 7. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Spiralian embryogenesis is found in a number of animal phyla, but the molecular mechanisms that pattern these embryos remain...
Organism or Cell Type:
Ilyanassa obsoleta
Citation Extract:
Chan XY, Lambert JD. Patterning a spiralian embryo: A segregated RNA for a Tis11 ortholog is required in the 3a and 3b cells of the Ilyanassa embryo. Dev Biol. 2010 Oct 7. [Epub ahead of print].

POU-V factors antagonize maternal VegT activity and beta-Catenin signaling in Xenopus embryos

Authors:
Cao Y, Siegel D, Donow C, Knöchel S, Yuan L, Knöchel W
Citation:
EMBO J. 2007 Jun 20;26(12):2942-54. Epub 2007 May 31
Epub:
Not Epub
Abstract:
VegT and beta-Catenin are key players in the hierarchy of factors that are required for induction and patterning of mesendoderm...
Organism or Cell Type:
Xenopus
Citation Extract:
Cao Y, Siegel D, Donow C, Knöchel S, Yuan L, Knöchel W. POU-V factors antagonize maternal VegT activity and beta-Catenin signaling in Xenopus embryos. EMBO J. 2007 Jun 20;26(12):2942-54. Epub 2007 May 31.

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