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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Zebrafish as a genomics research model
Citation:
Curr Pharm Biotechnol. 2004 Oct;5(5):409-13 Epub:
Not Epub Abstract:
The zebrafish (Danio rerio) is a recent addition to the genomic scientists' repertoire of vertebrate animal model systems... Delivery Method:
not applicable Organism or Cell Type:
zebrafish Citation Extract: Chen E, Ekker SC. Zebrafish as a genomics research model. Curr Pharm Biotechnol. 2004 Oct;5(5):409-13. |
Zebrafish Bmp4 regulates left-right asymmetry at two distinct developmental time points
Citation:
Dev Biol. 2007 May 15;305(2):577-88. Epub 2007 Mar 6. Epub:
Not Epub Abstract:
Left-right (LR) asymmetry is regulated by early asymmetric signals within the embryo. Even though the role of the bone... Organism or Cell Type:
zebrafish Citation Extract: Chocron S, Verhoeven MC, Rentzsch F, Hammerschmidt M, Bakkers J. Zebrafish Bmp4 regulates left-right asymmetry at two distinct developmental time points. Dev Biol. 2007 May 15;305(2):577-88. Epub 2007 Mar 6.. |
Zebrafish cdx1b regulates differentiation of various intestinal cell lineages
Citation:
Dev Dyn. 2009 Feb 27. [Epub ahead of print] Epub:
Not Epub Abstract:
Both antisense morpholino oligonucleotide (MO)-mediated knockdown and overexpression experiments were performed to analyze... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen YH, Lu YF, Ko TY, Tsai MY, Lin CY, Lin CC, Hwang SP. Zebrafish cdx1b regulates differentiation of various intestinal cell lineages. Dev Dyn. 2009 Feb 27. [Epub ahead of print]. |
Zebrafish cdx1b regulates expression of downstream factors of Nodal signaling during early endoderm formation
Citation:
Development. 2008 Mar;135(5):941-52. Epub 2008 Jan 30. Epub:
Not Epub Abstract:
We identified a zebrafish caudal-related homeobox (cdx1b) gene, which shares syntenic conservation with both human and mouse... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Cheng PY, Lin CC, Wu CS, Lu YF, Lin CY, Chung CC, Chu CY, Huang CJ, Tsai CY, Korzh S, Wu JL, Hwang SP. Zebrafish cdx1b regulates expression of downstream factors of Nodal signaling during early endoderm formation. Development. 2008 Mar;135(5):941-52. Epub 2008 Jan 30.. |
Zebrafish homologue irx1a is required for the differentiation of serotonergic neurons
Citation:
Dev Dyn. 2007 Sep;236(9):2661-7. Epub:
Not Epub Abstract:
Serotonergic (5HT) neurons produce neurotransmitter serotonin, which modulates various neuronal circuits. The specification and... Organism or Cell Type:
zebrafish Citation Extract: Cheng CW, Yan CH, Choy SW, Hui MN, Hui CC, Cheng SH. Zebrafish homologue irx1a is required for the differentiation of serotonergic neurons. Dev Dyn. 2007 Sep;236(9):2661-7.. |
2,3,7,8-Tetrachlorodibenzo-p-dioxin Activation of the Aryl Hydrocarbon Receptor/Aryl Hydrocarbon Receptor Nuclear Translocator Pathway Causes Developmental Toxicity through a CYP1A-Independent Mechanism in Zebrafish
Citation:
Mol Pharmacol. 2004 Sep;66(3):512-21 Epub:
Not Epub Abstract:
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that dimerizes with ARNT to mediate responses to... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Carney SA, Peterson RE, Heideman W. 2,3,7,8-Tetrachlorodibenzo-p-dioxin Activation of the Aryl Hydrocarbon Receptor/Aryl Hydrocarbon Receptor Nuclear Translocator Pathway Causes Developmental Toxicity through a CYP1A-Independent Mechanism in Zebrafish. Mol Pharmacol. 2004 Sep;66(3):512-21. |
A direct role for Sox10 in specification of neural crest-derived sensory neurons
Citation:
Development. 2006 Dec;133(23):4619-30. Epub 2006 Oct 25 Epub:
Not Epub Abstract:
sox10 is necessary for development of neural and pigment cell derivatives of the neural crest (NC). However, whereas a direct... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Carney TJ, Dutton KA, Greenhill E, Delfino-Machín M, Dufourcq P, Blader P, Kelsh RN. A direct role for Sox10 in specification of neural crest-derived sensory neurons. Development. 2006 Dec;133(23):4619-30. Epub 2006 Oct 25. |
A High-Throughput Screen for Tuberculosis Progression
Citation:
PLoS ONE. 2011;6(2):e16779. doi:10.1371/journal.pone.0016779 Epub:
Not Epub Abstract:
One-third of the world population is infected with Mycobacterium tuberculosis and multi-drug resistant strains are rapidly... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Carvalho R, de Sonneville J, Stockhammer OW, Savage NDL, Veneman WJ, Ottenhoff THM, Dirks RP, Meijer AH, Spaink HP. A High-Throughput Screen for Tuberculosis Progression. PLoS ONE. 2011;6(2):e16779. doi:10.1371/journal.pone.0016779. |
A male with unilateral microphthalmia reveals a role for TMX3 in eye development
Citation:
PLoS One. 2010 May 11;5(5):e10565 Epub:
Not Epub Abstract:
Anophthalmia and microphthalmia are important birth defects, but their pathogenesis remains incompletely understood. We studied... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Chao R, Nevin L, Agarwal P, Riemer J, Bai X, Delaney A, Akana M, JimenezLopez N, Bardakjian T, Schneider A, Chassaing N, Schorderet DF, FitzPatrick D, Kwok PY, Ellgaard L, Gould DB, Zhang Y, Malicki J, Baier H, Slavotinek A. A male with unilateral microphthalmia reveals a role for TMX3 in eye development. PLoS One. 2010 May 11;5(5):e10565. |
An essential and highly conserved role for Zic3 in left–right patterning, gastrulation and convergent extension morphogenesis
Citation:
Dev Biol. 2012 Apr 1;364(1):22-31. doi: 10.1016/j.ydbio.2012.01.011. Epub 2012 Jan 21. Epub:
Not Epub Abstract:
Mutations in ZIC3 result in X-linked heterotaxy in humans, a syndrome consisting of left–right (L–R) patterning defects,... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish, Xenopus Citation Extract: Cast AE, Gao C, Amack JD, Ware SM. An essential and highly conserved role for Zic3 in left–right patterning, gastrulation and convergent extension morphogenesis. Dev Biol. 2012 Apr 1;364(1):22-31. doi: 10.1016/j.ydbio.2012.01.011. Epub 2012 Jan 21.. |