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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Development of an efficient method for phosphorodiamidate bond formation by using inorganic salts
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Citation:
Bioorg Med Chem Lett. 2011;[Epub ahead of print] doi:10.1016/j.bmcl.2011.12.021 Epub:
Not Epub Abstract:
Phosphorodiamidate morpholino oligonucleotides (PMOs) have been extensively applied in antisense strategies for gene regulation... Citation Extract: Harakawa T, Tsunoda H, Ohkubo A, Seio K, Sekine M. Development of an efficient method for phosphorodiamidate bond formation by using inorganic salts. Bioorg Med Chem Lett. 2011;[Epub ahead of print] doi:10.1016/j.bmcl.2011.12.021. |
Differential Role of PTEN Phosphatase in Chemotactic Growth Cone Guidance
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Citation:
J Biol Chem. 2013 Jun 17. [Epub ahead of print] Epub:
Not Epub Abstract:
Negatively targeting the tumor suppressor and phosphoinositide phosphatase PTEN promotes axon re-growth after injury. How PTEN... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Henle SJ, Carlstrom LP, Cheever TR, Henley JR. Differential Role of PTEN Phosphatase in Chemotactic Growth Cone Guidance. J Biol Chem. 2013 Jun 17. [Epub ahead of print]. |
Disruption of Esrom and Ryk identifies the roof plate boundary as an intermediate target for commissure formation
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Citation:
Mol Cell Neurosci. 2008 Feb;37(2):271-83. Epub 2007 Oct 16. Epub:
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Growth cones are guided to their final destination by intermediate targets. Here, we identify intermediate targets and... Organism or Cell Type:
zebrafish Citation Extract: Hendricks M, Mathuru AS, Wang H, Silander O, Kee MZ, Jesuthasan S. Disruption of Esrom and Ryk identifies the roof plate boundary as an intermediate target for commissure formation. Mol Cell Neurosci. 2008 Feb;37(2):271-83. Epub 2007 Oct 16.. |
Eif4a3 is required for accurate splicing of the Xenopus laevis ryanodine receptor pre-mRNA
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Citation:
Dev Biol. 2012;[Epub ahead of print] Epub:
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The Exon Junction Complex (EJC) plays a critical role in multiple posttranscriptional events, including RNA subcellular l... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Haremaki T, Weinstein DC. Eif4a3 is required for accurate splicing of the Xenopus laevis ryanodine receptor pre-mRNA. Dev Biol. 2012;[Epub ahead of print] . |
Eye and neural defects associated with loss of GDF6
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Citation:
BMC Dev Biol. 2006 Sep 29;6:43. Epub:
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ABSTRACT: BACKGROUND: In Xenopus the bone morphogenetic protein growth and differentiation factor 6 (GDF6) is expressed at the... Organism or Cell Type:
Xenopus Citation Extract: Hanel ML, Hensey C. Eye and neural defects associated with loss of GDF6. BMC Dev Biol. 2006 Sep 29;6:43.. |
Fgf-dependent otic induction requires competence provided by Foxi1 and Dlx3b
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Citation:
BMC Dev Biol. 2007 Jan 19;7:5 Epub:
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BACKGROUND: The inner ear arises from a specialized set of cells, the otic placode, that forms at the lateral edge of the... Organism or Cell Type:
zebrafish Citation Extract: Hans S, Christison J, Liu D, Westerfield M. Fgf-dependent otic induction requires competence provided by Foxi1 and Dlx3b. BMC Dev Biol. 2007 Jan 19;7:5. |
Generation and Characterization of a zebrafish model of SMA carrying the human SMN2 gene
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Citation:
Molecular Neurodegeneration 2011, 6:24 doi:10.1186/1750-1326-6-24 Epub:
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Animal models of human diseases are essential as they allow analysis of the disease process at the cellular level and can... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Hao LT, Burghes AHM, Beattie CE. Generation and Characterization of a zebrafish model of SMA carrying the human SMN2 gene. Molecular Neurodegeneration 2011, 6:24 doi:10.1186/1750-1326-6-24. |
Genomic characterization of Wilms' tumor suppressor 1 targets in nephron progenitor cells during kidney development
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Citation:
Development. 2010 Apr;137(7):1189-203 Epub:
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The Wilms' tumor suppressor 1 (WT1) gene encodes a DNA- and RNA-binding protein that plays an essential role in nephron... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Mouse kidney explants, embryonic Citation Extract: Hartwig S, Ho J, Pandey P, Macisaac K, Taglienti M, Xiang M, Alterovitz G, Ramoni M, Fraenkel E, Kreidberg JA. Genomic characterization of Wilms' tumor suppressor 1 targets in nephron progenitor cells during kidney development. Development. 2010 Apr;137(7):1189-203. |
Glucose metabolism impacts the spatio-temporal onset and magnitude of HSC induction in vivo
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Citation:
Blood. 2012;[Epub ahead of print] doi:10.1182/blood-2012-12-471201 Epub:
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Many pathways regulating blood formation have been elucidated, yet how each coordinates with embryonic biophysiology to... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Harris JM, Esain V, Frechette GM, Harris LJ, Cox AG, Cortes M, Garnaas MK, Carroll KJ, Cutting CC, Khan T, Elks PM, Renshaw SA, Dickinson BC, Chang CJ, Murphy MP, Paw BH, Heiden MGV, Goessling W, North TE. Glucose metabolism impacts the spatio-temporal onset and magnitude of HSC induction in vivo. Blood. 2012;[Epub ahead of print] doi:10.1182/blood-2012-12-471201. |
Glycome and transcriptome regulation of vasculogenesis
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Citation:
Circulation. 2009 Nov 10;120(19):1883-92. Epub 2009 Oct 26 Epub:
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BACKGROUND: Therapeutic vasculogenesis is an emerging concept that can potentially be harnessed for the management of ischemic... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Harfouche R, Hentschel DM, Piecewicz S, Basu S, Print C, Eavarone D, Kiziltepe T, Sasisekharan R, Sengupta S. Glycome and transcriptome regulation of vasculogenesis. Circulation. 2009 Nov 10;120(19):1883-92. Epub 2009 Oct 26. |