You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes

Authors:
Martin D, Pantoja C, Miñán AF, Valdes-Quezada C, Moltó E, Matesanz F, Bogdanović O, de la Calle-Mustienes E, Domínguez O, Taher L, Furlan-Magaril M, Alcina A, Cañón S, Fedetz M, Blasco MA, Pereira PS, Ovcharenko I, Recillas-Targa F, Montoliu L, Manzanares M, Guig� R, Serrano M, Casares F, Gómez-Skarmeta JL
Citation:
Nat Struct Mol Biol. 2011 Jun;18(6):708-14. Epub 2011 May 22
Epub:
Not Epub
Abstract:
Many genomic alterations associated with human diseases localize in noncoding regulatory elements located far from the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Martin D, Pantoja C, Miñán AF, Valdes-Quezada C, Moltó E, Matesanz F, Bogdanović O, de la Calle-Mustienes E, Domínguez O, Taher L, Furlan-Magaril M, Alcina A, Cañón S, Fedetz M, Blasco MA, Pereira PS, Ovcharenko I, Recillas-Targa F, Montoliu L, Manzanares M, Guig� R, Serrano M, Casares F, Gómez-Skarmeta JL. Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes. Nat Struct Mol Biol. 2011 Jun;18(6):708-14. Epub 2011 May 22.

Hematopoietic stem cells, hematopoiesis and disease: lessons from the zebrafish model

Authors:
Martin CS, Moriyama A, Zon LI
Citation:
Genome Med. 2011 Dec 29;3(1):83. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The zebrafish model is rapidly gaining prominence in the study of development, hematopoiesis, and disease. The zebrafish...
Organism or Cell Type:
zebrafish
Citation Extract:
Martin CS, Moriyama A, Zon LI. Hematopoietic stem cells, hematopoiesis and disease: lessons from the zebrafish model. Genome Med. 2011 Dec 29;3(1):83. [Epub ahead of print].

Hemicentin 2 and Fibulin 1 are required for epidermal-dermal junction formation and fin mesenchymal cell migration during zebrafish development

Authors:
Martins Feitosa N, Zhang J, Carney TJ, Metzger M, Korzh V, Bloch W, Hammerschmidt M
Citation:
Dev Biol. 2012 Jul 5. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Hemicentin 1 (Hmcn1) and Hemicentin 2 (Hmcn2) belong to the fibulin family of extracellular matrix (ECM) proteins that play...
Organism or Cell Type:
zebrafish
Citation Extract:
Martins Feitosa N, Zhang J, Carney TJ, Metzger M, Korzh V, Bloch W, Hammerschmidt M. Hemicentin 2 and Fibulin 1 are required for epidermal-dermal junction formation and fin mesenchymal cell migration during zebrafish development. Dev Biol. 2012 Jul 5. [Epub ahead of print].

Identification of RNA binding motif proteins essential for cardiovascular development

Authors:
Maragh S, Miller RA, Bessling SL, McGaughey DM, Wessels MW, de Graaf B, Stone EA, Bertoli-Avella AM, Gearhart JD, Fisher S, McCallion AS
Citation:
BMC Dev Biol. 2011;11:62 doi:10.1186/1471-213X-11-62
Epub:
Not Epub
Abstract:
Background We recently identified Rbm24 as a novel gene expressed during mouse cardiac development. Due to its tightly...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Maragh S, Miller RA, Bessling SL, McGaughey DM, Wessels MW, de Graaf B, Stone EA, Bertoli-Avella AM, Gearhart JD, Fisher S, McCallion AS. Identification of RNA binding motif proteins essential for cardiovascular development . BMC Dev Biol. 2011;11:62 doi:10.1186/1471-213X-11-62.

Initial investigations of 99m Tc-labeled morpholinos for radiopharmaceutical applications

Authors:
Mang'era KO, Liu G, Yi W, Zhang Y, Liu N, Gupta S, Rusckowski M, Hnatowich DJ
Citation:
Eur J Nucl Med 2001 Nov;28(11):1682-9
Epub:
Not Epub
Abstract:
This laboratory is evaluating phosphorothioate deoxyribonucleic acids (DNAs) and peptide nucleic acids (PNAs) for a variety of...
Delivery Method:
not applicable
Organism or Cell Type:
not applicable
Citation Extract:
Mang'era KO, Liu G, Yi W, Zhang Y, Liu N, Gupta S, Rusckowski M, Hnatowich DJ. Initial investigations of 99m Tc-labeled morpholinos for radiopharmaceutical applications. Eur J Nucl Med 2001 Nov;28(11):1682-9.

Loss of Function of Glucocerebrosidase GBA2 Is Responsible for Motor Neuron Defects in Hereditary Spastic Paraplegia

Authors:
Martin E, Schüle R, Smets K, Rastetter A, Boukhris A, Loureiro JL, Gonzalez MA, Mundwiller E, Deconinck T, Wessner M, Jornea L, Oteyza AC, Durr A, Martin JJ, Schöls L, Mhiri C, Lamari F, Züchner S, De Jonghe P, Kabashi E, Brice A, Stevanin G
Citation:
Am J Hum Genet. 2013;[Epub ahead of print] doi:10.1016/j.ajhg.2012.11.021
Epub:
Not Epub
Abstract:
Spastic paraplegia 46 refers to a locus mapped to chromosome 9 that accounts for a complicated autosomal-recessive form of...
Organism or Cell Type:
zebrafish
Citation Extract:
Martin E, Schüle R, Smets K, Rastetter A, Boukhris A, Loureiro JL, Gonzalez MA, Mundwiller E, Deconinck T, Wessner M, Jornea L, Oteyza AC, Durr A, Martin JJ, Schöls L, Mhiri C, Lamari F, Züchner S, De Jonghe P, Kabashi E, Brice A, Stevanin G. Loss of Function of Glucocerebrosidase GBA2 Is Responsible for Motor Neuron Defects in Hereditary Spastic Paraplegia. Am J Hum Genet. 2013;[Epub ahead of print] doi:10.1016/j.ajhg.2012.11.021.

Loss of the ciliary kinase Nek8 causes left-right asymmetry defects

Authors:
Manning DK, Sergeev M, van Heesbeen RG, Wong MD, Oh JH, Liu Y, Henkelman RM, Drummond I, Shah JV, Beier DR
Citation:
J Am Soc Nephrol. 2013 Jan;24(1):100-12. doi: 10.1681/ASN.2012050490
Epub:
Not Epub
Abstract:
A missense mutation in mouse Nek8, which encodes a ciliary kinase, produces the juvenile cystic kidneys (jck) model of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Manning DK, Sergeev M, van Heesbeen RG, Wong MD, Oh JH, Liu Y, Henkelman RM, Drummond I, Shah JV, Beier DR. Loss of the ciliary kinase Nek8 causes left-right asymmetry defects. J Am Soc Nephrol. 2013 Jan;24(1):100-12. doi: 10.1681/ASN.2012050490.

Maturin is a novel protein required for differentiation during primary neurogenesis

Authors:
Martinez-De Luna RI, Ku RY, Lyou Y, Zuber ME
Citation:
Dev Biol. 2013 Oct 1. doi:pii: S0012-1606(13)00514-9. 10.1016/j.ydbio.2013.09.028. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Proliferation and differentiation are tightly controlled during neural development. In the embryonic neural plate, primary...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Martinez-De Luna RI, Ku RY, Lyou Y, Zuber ME. Maturin is a novel protein required for differentiation during primary neurogenesis. Dev Biol. 2013 Oct 1. doi:pii: S0012-1606(13)00514-9. 10.1016/j.ydbio.2013.09.028. [Epub ahead of print].

Micro-injection of Morpholino Oligonucleotides for Depleting Securin in Mouse Oocytes

Authors:
Marangos P
Citation:
Meth Molec Biol. 2013;957:153-62. doi:10.1007/978-1-62703-191-2_10
Epub:
Not Epub
Abstract:
Gene silencing techniques have brought new insights into mammalian oocyte and embryo development. More specifically, the use of...
Delivery Method:
Microinjection
Organism or Cell Type:
mouse oocytes
Citation Extract:
Marangos P. Micro-injection of Morpholino Oligonucleotides for Depleting Securin in Mouse Oocytes. Meth Molec Biol. 2013;957:153-62. doi:10.1007/978-1-62703-191-2_10.

Myo1e Impairment Results in Actin Reorganization, Podocyte Dysfunction, and Proteinuria in Zebrafish and Cultured Podocytes

Authors:
Mao J, Wang D, Mataleena P, He B, Niu D, Katayama K, Xu X, Ojala JR, Wang W, Shu Q, Do L, Liu A, Pikkarainen T, Patrakka J, Tyrggvason K
Citation:
PLoS ONE. 2013;8(8):e72750. doi:10.1371/journal.pone.0072750
Epub:
Not Epub
Abstract:
Background Podocytes serve as an important constituent of the glomerular filtration barrier. Recently, we and others identified...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mao J, Wang D, Mataleena P, He B, Niu D, Katayama K, Xu X, Ojala JR, Wang W, Shu Q, Do L, Liu A, Pikkarainen T, Patrakka J, Tyrggvason K. Myo1e Impairment Results in Actin Reorganization, Podocyte Dysfunction, and Proteinuria in Zebrafish and Cultured Podocytes. PLoS ONE. 2013;8(8):e72750. doi:10.1371/journal.pone.0072750.

Pages