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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Proximodistal identity during vertebrate limb regeneration is regulated by Meis homeodomain proteins

Authors:
Mercader N, Tanaka EM, Torres M
Citation:
Development. 2005 Sep;132(18):4131-42. Epub 2005 Aug 17
Epub:
Not Epub
Abstract:
The mechanisms by which cells obtain instructions to precisely re-create the missing parts of an organ remain an unresolved...
Delivery Method:
Microinjection
Organism or Cell Type:
Ambystoma mexicanum (axolotl)
Citation Extract:
Mercader N, Tanaka EM, Torres M. Proximodistal identity during vertebrate limb regeneration is regulated by Meis homeodomain proteins. Development. 2005 Sep;132(18):4131-42. Epub 2005 Aug 17.

Quantitation of Intracellular Concentration of a Delivered Morpholino Oligomer by Capillary Electrophoresis-Laser- Induced Fluorescence: Correlation with Upregulation of Luciferase Gene Expression

Authors:
McKeon J, Cho MJ, Khaledi MG
Citation:
Anal Biochem 2001 Jun 1;293(1):1-7
Epub:
Not Epub
Abstract:
Antisense oligonucleotides have shown great promise over the past several years as viable drugs to combat various forms of...
Delivery Method:
Scrape Delivery
Organism or Cell Type:
cell culture: HeLa AntisenseTest System
Citation Extract:
McKeon J, Cho MJ, Khaledi MG. Quantitation of Intracellular Concentration of a Delivered Morpholino Oligomer by Capillary Electrophoresis-Laser- Induced Fluorescence: Correlation with Upregulation of Luciferase Gene Expression. Anal Biochem 2001 Jun 1;293(1):1-7.

Radioprotection in Normal Tissue and Delayed Tumor Growth by Blockade of CD47 Signaling

Authors:
Maxhimer JB, Soto-Pantoja DR, Ridnour LA, Shih HB, DeGraff WG, Tsokos M, Wink DA, Isenberg JS, Roberts DD
Citation:
Sci Transl Med. 2009;1(3):3ra7
Epub:
Not Epub
Abstract:
Radiation-induced damage of normal tissues restricts the therapeutic doses of ionizing radiation that can be delivered to...
Organism or Cell Type:
cell culture, mice
Citation Extract:
Maxhimer JB, Soto-Pantoja DR, Ridnour LA, Shih HB, DeGraff WG, Tsokos M, Wink DA, Isenberg JS, Roberts DD. Radioprotection in Normal Tissue and Delayed Tumor Growth by Blockade of CD47 Signaling. Sci Transl Med. 2009;1(3):3ra7.

Regulation of cytokinesis by Rho GTPase flux

Authors:
Miller AL, Bement WM
Citation:
Nat Cell Biol. 2009 Jan;11(1):71-7. Epub 2008 Dec 7
Epub:
Not Epub
Abstract:
In animal cells, cytokinesis is powered by a contractile ring of actin filaments (F-actin) and myosin-2. Formation of the...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Miller AL, Bement WM. Regulation of cytokinesis by Rho GTPase flux. Nat Cell Biol. 2009 Jan;11(1):71-7. Epub 2008 Dec 7.

Repression of Wnt/{beta}-catenin signaling in the anterior endoderm is essential for liver and pancreas development

Authors:
McLin VA, Rankin SA, Zorn AM
Citation:
Development. 2007 Jun;134(12):2207-17. Epub 2007 May 16
Epub:
Not Epub
Abstract:
The liver and pancreas are specified from the foregut endoderm through an interaction with the adjacent mesoderm. However, the...
Organism or Cell Type:
Xenopus
Citation Extract:
McLin VA, Rankin SA, Zorn AM. Repression of Wnt/{beta}-catenin signaling in the anterior endoderm is essential for liver and pancreas development. Development. 2007 Jun;134(12):2207-17. Epub 2007 May 16.

Sequential actions of Pax3 and Pax7 drive xanthophore development in zebrafish neural crest

Authors:
Minchin JE, Hughes SM
Citation:
Dev Biol.2008 May 15;317(2):508-22. Epub 2008 Mar 14.
Epub:
Not Epub
Abstract:
The Pax3/7 gene family has a fundamental and conserved role during neural crest formation. In people, PAX3 mutation causes...
Organism or Cell Type:
zebrafish
Citation Extract:
Minchin JE, Hughes SM. Sequential actions of Pax3 and Pax7 drive xanthophore development in zebrafish neural crest. Dev Biol.2008 May 15;317(2):508-22. Epub 2008 Mar 14..

Signal-dependent regulation of splicing via phosphorylation of Sam68

Authors:
Matter N, Herrlich P, Konig H
Citation:
Nature. 2002 Dec 12;420(6916):691-5
Epub:
Not Epub
Abstract:
Evolution of human organismal complexity from a relatively small number of genes--only approximately twice that of worm or fly...
Delivery Method:
Electroporation
Organism or Cell Type:
cell culture: mouse EL-4 T-lymphoma cells
Citation Extract:
Matter N, Herrlich P, Konig H. Signal-dependent regulation of splicing via phosphorylation of Sam68. Nature. 2002 Dec 12;420(6916):691-5.

Skin exposure to micro- and nano-particles can cause haemostasis in zebrafish larvae

Authors:
McLeish JA, Chico TJ, Taylor HB, Tucker C, Donaldson K, Brown SB
Citation:
Thromb Haemost. 2010 Feb 19;103(4). [Epub ahead of print]
Epub:
Not Epub
Abstract:
Low mass ambient exposure to airborne particles is associated with atherothrombotic events that may be a consequence of the...
Organism or Cell Type:
zebrafish
Citation Extract:
McLeish JA, Chico TJ, Taylor HB, Tucker C, Donaldson K, Brown SB. Skin exposure to micro- and nano-particles can cause haemostasis in zebrafish larvae. Thromb Haemost. 2010 Feb 19;103(4). [Epub ahead of print].

Smad1 and Smad5 differentially regulate embryonic hematopoiesis

Authors:
McReynolds LJ, Gupta S, Figueroa ME, Mullins MC, Evans T
Citation:
Blood. 2007 Dec 1;110(12):3881-90. Epub 2007 Aug 29
Epub:
Not Epub
Abstract:
The BMP signaling pathway regulates multiple steps of hematopoiesis, mediated through receptor-regulated Smads, including Smad1...
Organism or Cell Type:
zebrafish
Citation Extract:
McReynolds LJ, Gupta S, Figueroa ME, Mullins MC, Evans T. Smad1 and Smad5 differentially regulate embryonic hematopoiesis. Blood. 2007 Dec 1;110(12):3881-90. Epub 2007 Aug 29.

Small heat shock protein HSPB1 regulates growth of embryonic zebrafish craniofacial muscles

Authors:
Middleton RC, Shelden EA
Citation:
Exp Cell Res. 2013;[Epub ahead of print] http://dx.doi.org/10.1016/j.yexcr.2013.01.002
Epub:
Not Epub
Abstract:
The small heat shock protein HspB1 (Hsp27) is abundantly expressed in embryonic muscle tissues of a wide variety of vertebrate...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Middleton RC, Shelden EA. Small heat shock protein HSPB1 regulates growth of embryonic zebrafish craniofacial muscles. Exp Cell Res. 2013;[Epub ahead of print] http://dx.doi.org/10.1016/j.yexcr.2013.01.002.

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