You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney

Authors:
Sun Z, Amsterdam A, Pazour GJ, Cole DG, Miller MS, Hopkins N
Citation:
Development. 2004 Aug;131(16):4085-93. Epub 2004 Jul 21
Epub:
Not Epub
Abstract:
Polycystic kidney disease (PKD) is a common human genetic illness. It is characterized by the formation of multiple kidney...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun Z, Amsterdam A, Pazour GJ, Cole DG, Miller MS, Hopkins N. A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney. Development. 2004 Aug;131(16):4085-93. Epub 2004 Jul 21.

A histone demethylase is necessary for regeneration in zebrafish

Authors:
Stewart S, Tsun ZY, Izpisua Belmonte JC
Citation:
Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19889-94. Epub 2009 Nov 6
Epub:
Not Epub
Abstract:
Urodele amphibians and teleost fish regenerate amputated body parts via a process called epimorphic regeneration. A hallmark of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stewart S, Tsun ZY, Izpisua Belmonte JC. A histone demethylase is necessary for regeneration in zebrafish. Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19889-94. Epub 2009 Nov 6.

A morpholino oligomer targeting highly conserved internal ribosome entry site sequence is able to inhibit multiple species of picornavirus

Authors:
Stone JK, Rijnbrand R, Stein DA, Ma Y, Yang Y, Iversen PL, Andino R
Citation:
Antimicrob Agents Chemother. 2008 Jun;52(6):1970-81. Epub 2008 Mar 17.
Epub:
Not Epub
Abstract:
Members of the genera Enterovirus and Rhinovirus (family Picornaviridae) cause a wide range of human diseases. An established...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice, cell cultures
Citation Extract:
Stone JK, Rijnbrand R, Stein DA, Ma Y, Yang Y, Iversen PL, Andino R. A morpholino oligomer targeting highly conserved internal ribosome entry site sequence is able to inhibit multiple species of picornavirus. Antimicrob Agents Chemother. 2008 Jun;52(6):1970-81. Epub 2008 Mar 17..

A mutant form of MeCP2 protein associated with human Rett syndrome cannot be displaced from methylated DNA by notch in Xenopus embryos

Authors:
Stancheva I, Collins AL, Van den Veyver IB, Zoghbi H, Meehan RR
Citation:
Mol Cell. 2003 Aug;12(2):425-35
Epub:
Not Epub
Abstract:
MeCP2 is a DNA binding protein that represses transcription of methylated genes in vitro, but the endogenous function of MeCP2...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Stancheva I, Collins AL, Van den Veyver IB, Zoghbi H, Meehan RR. A mutant form of MeCP2 protein associated with human Rett syndrome cannot be displaced from methylated DNA by notch in Xenopus embryos. Mol Cell. 2003 Aug;12(2):425-35.

A perturbation model of the gene regulatory network for oral and aboral ectoderm specification in the sea urchin embryo

Authors:
Su YH, Li E, Geiss GK, Longabaugh WJ, Krämer A, Davidson EH
Citation:
Dev Biol. 2009 Mar 4. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The current gene regulatory network (GRN) for the sea urchin embryo pertains to pregastrular specification functions in the...
Organism or Cell Type:
sea urchin
Citation Extract:
Su YH, Li E, Geiss GK, Longabaugh WJ, Krämer A, Davidson EH. A perturbation model of the gene regulatory network for oral and aboral ectoderm specification in the sea urchin embryo. Dev Biol. 2009 Mar 4. [Epub ahead of print].

A PHD12–Snail2 repressive complex epigenetically mediates neural crest epithelial-to-mesenchymal transition

Authors:
Strobl-Mazzulla PH, Bronner ME
Citation:
J Cell Biol. 2012;198(6):999-1010. doi: 10.1083/jcb.201203098
Epub:
Not Epub
Abstract:
Neural crest cells form within the neural tube and then undergo an epithelial to mesenchymal transition (EMT) to initiate...
Delivery Method:
Electroporation
Organism or Cell Type:
chick (Gallus gallus)
Citation Extract:
Strobl-Mazzulla PH, Bronner ME. A PHD12–Snail2 repressive complex epigenetically mediates neural crest epithelial-to-mesenchymal transition. J Cell Biol. 2012;198(6):999-1010. doi: 10.1083/jcb.201203098 .

A specificity comparison of four antisense types: morpholino, 2'-O-methyl RNA, DNA, and phosphorothioate DNA

Authors:
Stein D, Foster E, Huang SB, Weller D, Summerton J
Citation:
Antisense Nucleic Acid Drug Dev. 1997 Jun;7(3):151-7
Epub:
Not Epub
Abstract:
Cell-free translation studies were carried out to compare the efficacy and specificity of four antisense structural types: DNA...
Delivery Method:
in vitro: TNT
Citation Extract:
Stein D, Foster E, Huang SB, Weller D, Summerton J. A specificity comparison of four antisense types: morpholino, 2'-O-methyl RNA, DNA, and phosphorothioate DNA. Antisense Nucleic Acid Drug Dev. 1997 Jun;7(3):151-7.

Antagonism of microRNA Function in Zebrafish Embryos by Using Locked Nucleic Acid Enzymes (LNAzymes)

Authors:
Suryawanshi H, Lalwani MK, Ramasamy S, Rana R, Scaria V, Sivasubbu S, Maiti S
Citation:
ChemBioChem. 2012;[Epub ahead of print] doi:10.1002/cbic.201100789
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) have crucial functions in many cellular processes, such as differentiation, proliferation and apoptosis;...
Organism or Cell Type:
zebrafish
Citation Extract:
Suryawanshi H, Lalwani MK, Ramasamy S, Rana R, Scaria V, Sivasubbu S, Maiti S. Antagonism of microRNA Function in Zebrafish Embryos by Using Locked Nucleic Acid Enzymes (LNAzymes). ChemBioChem. 2012;[Epub ahead of print] doi:10.1002/cbic.201100789.

Anti-sense morpholino oligonucleotide assay shows critical involvement for NF-kappaB activation in the production of Wnt-1 protein by HepG2 cells: oncology implications

Authors:
Sun CS, Wu KT, Lee HH, Uen YH, Tian YF, Tzeng CC, Wang AH, Cheng CJ, Tsai SL
Citation:
J Biomed Sci. 2008 Sep;15(5):633-43. Epub 2008 May 7.
Epub:
Not Epub
Abstract:
The link of proto-oncogenic protein Wnt-1 production with NF-kappaB activation has been functionally demonstrated in PC12 cells...
Citation Extract:
Sun CS, Wu KT, Lee HH, Uen YH, Tian YF, Tzeng CC, Wang AH, Cheng CJ, Tsai SL. Anti-sense morpholino oligonucleotide assay shows critical involvement for NF-kappaB activation in the production of Wnt-1 protein by HepG2 cells: oncology implications. J Biomed Sci. 2008 Sep;15(5):633-43. Epub 2008 May 7..

Antihypertensive Actions of Moderate Hyperbilirubinemia: Role of Superoxide Inhibition

Authors:
Stec DE, Storm MV, Pruett BE, Gousset MU
Citation:
Am J Hypertens. 2013 Mar 12. [Epub ahead of print] doi: 10.1093/ajh/hpt038
Epub:
Not Epub
Abstract:
BACKGROUND Moderate (approximately 2-fold) increases in plasma unconjugated bilirubin levels are able to attenuate the...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice C57BL/6J
Citation Extract:
Stec DE, Storm MV, Pruett BE, Gousset MU. Antihypertensive Actions of Moderate Hyperbilirubinemia: Role of Superoxide Inhibition. Am J Hypertens. 2013 Mar 12. [Epub ahead of print] doi: 10.1093/ajh/hpt038.

Pages