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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Zebrafish model for congenital myasthenic syndrome reveals mechanisms causal to developmental recovery

Authors:
Walogorsky M, Mongeon R, Wen H, Nelson NR, Urban JM, Ono F, Mandel G, Brehm P
Citation:
Proc Nat Acad Sci USA. 2012;109(43):17711-6 doi:10.1073/pnas.1215858109
Epub:
Not Epub
Abstract:
Mutations in muscle ACh receptors cause slow-channel syndrome (SCS) and Escobar syndrome, two forms of congenital myasthenia....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Walogorsky M, Mongeon R, Wen H, Nelson NR, Urban JM, Ono F, Mandel G, Brehm P. Zebrafish model for congenital myasthenic syndrome reveals mechanisms causal to developmental recovery. Proc Nat Acad Sci USA. 2012;109(43):17711-6 doi:10.1073/pnas.1215858109.

Zebrafish Thsd7a is a neural protein required for angiogenic patterning during development

Authors:
Wang CH, Chen IH, Kuo MW, Su PT, Lai ZY, Wang CH, Huang WC, Hoffman J, Kuo CJ, You MS, Chuang YJ
Citation:
Dev Dyn. 2011;240:[Epub ahead of print] doi: 10.1002/dvdy.22641
Epub:
Not Epub
Abstract:
Angiogenesis is a highly organized process under the control of guidance cues that direct endothelial cell (EC) migration....
Organism or Cell Type:
zebrafish
Citation Extract:
Wang CH, Chen IH, Kuo MW, Su PT, Lai ZY, Wang CH, Huang WC, Hoffman J, Kuo CJ, You MS, Chuang YJ. Zebrafish Thsd7a is a neural protein required for angiogenic patterning during development. Dev Dyn. 2011;240:[Epub ahead of print] doi: 10.1002/dvdy.22641.

[Morpholino oligonucleotide-based screen of novel genes with developmental function]

Authors:
Wada S, Yamada L, Kobayashi K, Shoguchi E, Satoh N
Citation:
Seikagaku. 2003 Jul;75(7):617-20
Epub:
Not Epub
Abstract:
[Article in Japanese]
Delivery Method:
Microinjection
Organism or Cell Type:
Ciona savignyi
Citation Extract:
Wada S, Yamada L, Kobayashi K, Shoguchi E, Satoh N. [Morpholino oligonucleotide-based screen of novel genes with developmental function]. Seikagaku. 2003 Jul;75(7):617-20.

A complex extracellular sphingomyelinase of Pseudomonas aeruginosa inhibits angiogenesis by selective cytotoxicity to endothelial cells

Authors:
Vasil ML, Stonehouse MJ, Vasil AI, Wadsworth SJ, Goldfine H, Bolcome RE 3rd, Chan J
Citation:
PLoS Pathog. 2009 May;5(5):e1000420. Epub 2009 May 8
Epub:
Not Epub
Abstract:
The hemolytic phospholipase C (PlcHR) expressed by Pseudomonas aeruginosa is the original member of a Phosphoesterase...
Organism or Cell Type:
zebrafish
Citation Extract:
Vasil ML, Stonehouse MJ, Vasil AI, Wadsworth SJ, Goldfine H, Bolcome RE 3rd, Chan J. A complex extracellular sphingomyelinase of Pseudomonas aeruginosa inhibits angiogenesis by selective cytotoxicity to endothelial cells. PLoS Pathog. 2009 May;5(5):e1000420. Epub 2009 May 8.

A Congenital Neutrophil Defect Syndrome Associated with Mutations in VPS45

Authors:
Vilboux T, Lev A, Malicdan MCV, Simon AJ, Järvinen P, Racek T, Puchalka J, Sood R, Carrington B, Bishop K, Mullikin J, Huizing M, Garty BZ, Eyal E, Wolach B, Gavrieli R, Toren A, Soudack M, Atawneh OM, Babushkin T, Schiby G, Cullinane A, Avivi C, Polak-Charcon S, Barshack I, Amariglio N, Rechavi G, van der Werff ten Bosch J, Anikster Y, Klein C, Gahl WA, Somech R.
Citation:
N Engl J Med. 2013;[Epub ahead of print]doi:10.1056/NEJMoa1301296
Epub:
Not Epub
Abstract:
Background Neutrophils are the predominant phagocytes that provide protection against bacterial and fungal infections....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Vilboux T, Lev A, Malicdan MCV, Simon AJ, Järvinen P, Racek T, Puchalka J, Sood R, Carrington B, Bishop K, Mullikin J, Huizing M, Garty BZ, Eyal E, Wolach B, Gavrieli R, Toren A, Soudack M, Atawneh OM, Babushkin T, Schiby G, Cullinane A, Avivi C, Polak-Charcon S, Barshack I, Amariglio N, Rechavi G, van der Werff ten Bosch J, Anikster Y, Klein C, Gahl WA, Somech R. . A Congenital Neutrophil Defect Syndrome Associated with Mutations in VPS45. N Engl J Med. 2013;[Epub ahead of print]doi:10.1056/NEJMoa1301296.

A critical role for myoglobin in zebrafish development

Authors:
Vlecken DH, Testerink J, Ott EB, Sakalis PA, Jaspers RT, Bagowski CP
Citation:
Int J Dev Biol. 2009 Apr 2. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The globin family, including hemoglobin, myoglobin, neuroglobin and cytoglobin, plays an important role in oxygen storage and...
Organism or Cell Type:
zebrafish
Citation Extract:
Vlecken DH, Testerink J, Ott EB, Sakalis PA, Jaspers RT, Bagowski CP. A critical role for myoglobin in zebrafish development. Int J Dev Biol. 2009 Apr 2. [Epub ahead of print].

A mutation in the RNF170 gene causes autosomal dominant sensory ataxia

Authors:
Valdmanis PN, Dupré N, Lachance M, Stochmanski SJ, Belzil VV, Dion PA, Thiffault I, Brais B, Weston L, Saint-Amant L, Samuels ME, Rouleau GA
Citation:
Brain. 2011 Feb;134(Pt 2):602-7. Epub 2010 Nov 28
Epub:
Not Epub
Abstract:
Autosomal dominant sensory ataxia is a rare genetic condition that results in a progressive ataxia that is caused by...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Valdmanis PN, Dupré N, Lachance M, Stochmanski SJ, Belzil VV, Dion PA, Thiffault I, Brais B, Weston L, Saint-Amant L, Samuels ME, Rouleau GA. A mutation in the RNF170 gene causes autosomal dominant sensory ataxia. Brain. 2011 Feb;134(Pt 2):602-7. Epub 2010 Nov 28.

A novel complex, RUNX1-MYEF2, represses hematopoietic genes in erythroid cells

Authors:
van Riel B, Pakozdi T, Brouwer R, Monteiro R, Tuladhar K, Franke V, Bryne JC, Jorna R, Rijkers EJ, van Ijcken W, Andrieu-Soler C, Demmers J, Patient R, Soler E, Lenhard B, Grosveld F
Citation:
Mol Cell Biol. 2012 Oct;32(19):3814-22. doi: 10.1128/MCB.05938-11. Epub 2012 Jul 16
Epub:
Not Epub
Abstract:
RUNX1 is known to be an essential transcription factor for generating hematopoietic stem cells (HSC), but much less is known...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
van Riel B, Pakozdi T, Brouwer R, Monteiro R, Tuladhar K, Franke V, Bryne JC, Jorna R, Rijkers EJ, van Ijcken W, Andrieu-Soler C, Demmers J, Patient R, Soler E, Lenhard B, Grosveld F. A novel complex, RUNX1-MYEF2, represses hematopoietic genes in erythroid cells. Mol Cell Biol. 2012 Oct;32(19):3814-22. doi: 10.1128/MCB.05938-11. Epub 2012 Jul 16.

A novel mechanism for the transcriptional regulation of Wnt signaling in development

Authors:
Vacik T, Stubbs JL, Lemke G
Citation:
Genes Dev. 2011 Sep 1;25(17):1783-95. Epub 2011 Aug 19.
Epub:
Not Epub
Abstract:
Axial patterning of the embryonic brain requires a precise balance between canonical Wnt signaling, which dorsalizes the...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Vacik T, Stubbs JL, Lemke G. A novel mechanism for the transcriptional regulation of Wnt signaling in development. Genes Dev. 2011 Sep 1;25(17):1783-95. Epub 2011 Aug 19..

A Spatial and Temporal Gradient of Fgf Differentially Regulates Distinct Stages of Neural Development in the Zebrafish Inner Ear

Authors:
Vemaraju S, Kantarci H, Padanad MS, Riley BB
Citation:
PLoS Genet. 2012;8(11):e1003068. doi:10.1371/journal.pgen.1003068
Epub:
Not Epub
Abstract:
Neuroblasts of the statoacoustic ganglion (SAG) initially form in the floor of the otic vesicle during a relatively brief...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Vemaraju S, Kantarci H, Padanad MS, Riley BB. A Spatial and Temporal Gradient of Fgf Differentially Regulates Distinct Stages of Neural Development in the Zebrafish Inner Ear. PLoS Genet. 2012;8(11):e1003068. doi:10.1371/journal.pgen.1003068.

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