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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

The microRNA-producing enzyme Dicer1 is essential for zebrafish development.

Authors:
Wienholds E, Koudijs MJ, van Eeden FJ, Cuppen E, Plasterk RH.
Citation:
Nat Genet. 2003 Nov;35(3):217-8. Epub 2003 Oct 05.
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) are produced by the Dicer1 enzyme; the role of Dicer1 in vertebrate development is unknown. Here we report...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wienholds E, Koudijs MJ, van Eeden FJ, Cuppen E, Plasterk RH.. The microRNA-producing enzyme Dicer1 is essential for zebrafish development.. Nat Genet. 2003 Nov;35(3):217-8. Epub 2003 Oct 05..

The myosin co-chaperone UNC-45 is required for skeletal and cardiac muscle function in zebrafish

Authors:
Wohlgemuth SL, Crawford BD, Pilgrim DB
Citation:
Dev Biol. 2007 Mar 15;303(2):483-92. Epub 2006 Nov 22.
Epub:
Not Epub
Abstract:
The assembly of myosin into higher order structures is dependent upon accessory factors that are often tissue-specific. UNC-45...
Organism or Cell Type:
zebrafish
Citation Extract:
Wohlgemuth SL, Crawford BD, Pilgrim DB. The myosin co-chaperone UNC-45 is required for skeletal and cardiac muscle function in zebrafish. Dev Biol. 2007 Mar 15;303(2):483-92. Epub 2006 Nov 22..

The role of vasculature and blood circulation in zebrafish swimbladder development

Authors:
Winata CL, Korzh S, Kondrychyn I, Korzh V, Gong Z
Citation:
BMC Dev Biol. 2010 Jan 14;10(1):3. [Epub ahead of print]
Epub:
Not Epub
Abstract:
ABSTRACT: BACKGROUND: Recently we have performed a detailed analysis of early development of zebrafish swimbladder, a...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Winata CL, Korzh S, Kondrychyn I, Korzh V, Gong Z. The role of vasculature and blood circulation in zebrafish swimbladder development. BMC Dev Biol. 2010 Jan 14;10(1):3. [Epub ahead of print].

The Sp1-Related Transcription Factors sp5 and sp5-like Act Downstream of Wnt/beta-Catenin Signaling in Mesoderm and Neuroectoderm Patterning

Authors:
Weidinger G, Thorpe CJ, Wuennenberg-Stapleton K, Ngai J, Moon RT
Citation:
Curr Biol. 2005 Mar 29;15(6):489-500
Epub:
Not Epub
Abstract:
Background: Wnt/beta-catenin signaling regulates many processes during vertebrate development, including patterning of the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Weidinger G, Thorpe CJ, Wuennenberg-Stapleton K, Ngai J, Moon RT. The Sp1-Related Transcription Factors sp5 and sp5-like Act Downstream of Wnt/beta-Catenin Signaling in Mesoderm and Neuroectoderm Patterning. Curr Biol. 2005 Mar 29;15(6):489-500.

The zebrafish Pard3 ortholog is required for separation of the eye fields and retinal lamination

Authors:
Wei X, Cheng Y, Luo Y, Shi X, Nelson S, Hyde DR
Citation:
Dev Biol. 2004 May 1;269(1):286-301.
Epub:
Not Epub
Abstract:
The vertebrate retina develops from a sheet of neuroepithelial cells. Because adherens and tight junctions are critical for...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wei X, Cheng Y, Luo Y, Shi X, Nelson S, Hyde DR. The zebrafish Pard3 ortholog is required for separation of the eye fields and retinal lamination. Dev Biol. 2004 May 1;269(1):286-301..

Transforming growth factor-beta activation of phosphatidylinositol 3-kinase is independent of Smad2 and Smad3 and regulates fibroblast responses via p21-activated kinase-2

Authors:
Wilkes MC, Mitchell H, Penheiter SG, Dore JJ, Suzuki K, Edens M, Sharma DK, Pagano RE, Leof EB
Citation:
Cancer Res. 2005 Nov 15;65(22):10431-40
Epub:
Not Epub
Abstract:
Transforming growth factor-beta (TGF-beta) stimulates cellular proliferation and transformation to a myofibroblast phenotype in...
Delivery Method:
LipofectAMINE
Organism or Cell Type:
cell culture: human fibroblasts
Citation Extract:
Wilkes MC, Mitchell H, Penheiter SG, Dore JJ, Suzuki K, Edens M, Sharma DK, Pagano RE, Leof EB. Transforming growth factor-beta activation of phosphatidylinositol 3-kinase is independent of Smad2 and Smad3 and regulates fibroblast responses via p21-activated kinase-2. Cancer Res. 2005 Nov 15;65(22):10431-40.

Transient axonal glycoprotein-1 (TAG-1) and laminin-alpha1 regulate dynamic growth cone behaviors and initial axon direction in vivo

Authors:
Wolman MA, Sittaramane VK, Essner JJ, Yost HJ, Chandrasekhar A, Halloran MC
Citation:
Neural Develop. 2008 Feb 20;3:6
Epub:
Not Epub
Abstract:
BACKGROUND: How axon guidance signals regulate growth cone behavior and guidance decisions in the complex in vivo environment...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wolman MA, Sittaramane VK, Essner JJ, Yost HJ, Chandrasekhar A, Halloran MC. Transient axonal glycoprotein-1 (TAG-1) and laminin-alpha1 regulate dynamic growth cone behaviors and initial axon direction in vivo. Neural Develop. 2008 Feb 20;3:6.

Treatment of highly pathogenic filovirus infections using advanced antisense technology

Authors:
Warren T, Warfield K, Wells J, Swenson D, Lovejoy C, Iversen P, Bavari S.
Citation:
Retrovirology. 2010; 7(Suppl 1): P4. Published online 2010 May 11. doi: 10.1186/1742-4690-7-S1-P4
Epub:
Not Epub
Abstract:
Filoviruses, comprised of the Ebola viruses (EBOV) and Marburg virus (MARV), are highly pathogenic agents with human case...
Delivery Method:
Injection
Organism or Cell Type:
mice, guinea pigs, rhesus macaques, cynomolgus macaques
Citation Extract:
Warren T, Warfield K, Wells J, Swenson D, Lovejoy C, Iversen P, Bavari S.. Treatment of highly pathogenic filovirus infections using advanced antisense technology. Retrovirology. 2010; 7(Suppl 1): P4. Published online 2010 May 11. doi: 10.1186/1742-4690-7-S1-P4.

Tumor delivery of antisense oligomer using trastuzumab within a streptavidin nanoparticle

Authors:
Wang Y, Liu X, Chen L, Cheng D, Rusckowski M, Hnatowich DJ
Citation:
Eur J Nucl Med Mol Imaging. 2009 Dec;36(12):1977-86. doi: 10.1007/s00259-009-1201-2
Epub:
Not Epub
Abstract:
PURPOSE: Trastuzumab (Herceptin) is often internalized following binding to Her2+ tumor cells. The objective of this study was...
Link:
http://link.springer.com/article/10.1007%2Fs00259-009-1201-2
Delivery Method:
Nanoparticle
Organism or Cell Type:
cell culture (SUM190, SUM149) and xenografts in mice
Citation Extract:
Wang Y, Liu X, Chen L, Cheng D, Rusckowski M, Hnatowich DJ. Tumor delivery of antisense oligomer using trastuzumab within a streptavidin nanoparticle. Eur J Nucl Med Mol Imaging. 2009 Dec;36(12):1977-86. doi: 10.1007/s00259-009-1201-2.

Twisted gastrulation is required for forebrain specification and cooperates with Chordin to inhibit BMP signaling during X. tropicalis gastrulation

Authors:
Wills A, Harland RM, Khokha MK
Citation:
Dev Biol. 2006 Jan 1;289(1):166-78.
Epub:
Not Epub
Abstract:
In the developing vertebrate embryo, proper dorsal-ventral patterning relies on BMP antagonists secreted by the organizer...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Wills A, Harland RM, Khokha MK. Twisted gastrulation is required for forebrain specification and cooperates with Chordin to inhibit BMP signaling during X. tropicalis gastrulation. Dev Biol. 2006 Jan 1;289(1):166-78..

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