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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

The expression of Glia Maturation Factors and the effect of Glia Maturation Factor-γ on angiogenic sprouting in Zebrafish

Authors:
Zuo P, Fu Z, Tao T, Ye F, Chen L, Wang X, Lu W, Xie X
Citation:
Exp Cell Res. 2013 Jan 16. doi:pii: S0014-4827(13)00007-4. 10.1016/j.yexcr.2013.01.004. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Angiogenesis is a vital process for proper embryonic development, wound healing, malignant tumor growth and metastasis. Two...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zuo P, Fu Z, Tao T, Ye F, Chen L, Wang X, Lu W, Xie X. The expression of Glia Maturation Factors and the effect of Glia Maturation Factor-γ on angiogenic sprouting in Zebrafish. Exp Cell Res. 2013 Jan 16. doi:pii: S0014-4827(13)00007-4. 10.1016/j.yexcr.2013.01.004. [Epub ahead of print].

基因研究的工具——吗啉反义寡核苷酸(PMO)

Authors:
黄世杰.
Citation:
International Journal of Pharmaceutical Research. 2006;4: (Chinese)
Epub:
Not Epub
Abstract:
PMO(phosphorodiamidate morpholino oligomers)是一种新型反义寡核苷酸,抑制天然RNA剪接过程,产生各种mRNA,可抑制基因表达,如抑制原癌基因的表达.
Citation Extract:
黄世杰.. 基因研究的工具——吗啉反义寡核苷酸(PMO). International Journal of Pharmaceutical Research. 2006;4: (Chinese).

A central function for perlecan in skeletal muscle and cardiovascular development

Authors:
Zoeller JJ, McQuillan A, Whitelock J, Ho SY, Iozzo RV
Citation:
J Cell Biol. 2008 Apr 21;181(2):381-94
Epub:
Not Epub
Abstract:
Perlecan's developmental functions are difficult to dissect in placental animals because perlecan disruption is embryonic...
Organism or Cell Type:
zebrafish
Citation Extract:
Zoeller JJ, McQuillan A, Whitelock J, Ho SY, Iozzo RV. A central function for perlecan in skeletal muscle and cardiovascular development. J Cell Biol. 2008 Apr 21;181(2):381-94.

A central role for decorin during vertebrate convergent extension

Authors:
Zoeller JJ, Pimtong W, Corby H, Goldoni S, Iozzo AE, Owens RT, Ho SY, Iozzo RV
Citation:
J Biol Chem. 2009 Feb 10. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Decorin, an archetypal member of the small leucine-rich proteoglycan gene family, regulates collagen fibrillogenesis and cell...
Organism or Cell Type:
zebrafish
Citation Extract:
Zoeller JJ, Pimtong W, Corby H, Goldoni S, Iozzo AE, Owens RT, Ho SY, Iozzo RV. A central role for decorin during vertebrate convergent extension. J Biol Chem. 2009 Feb 10. [Epub ahead of print].

A comprehensive analysis of GATA-1-regulated miRNAs reveals miR-23a to be a positive modulator of erythropoiesis

Authors:
Zhu Y, Wang D, Wang F, Li T, Dong L, Liu H, Ma Y, Jiang F, Yin H, Yan W, Luo M, Tang Z, Zhang G, Wang Q, Zhang J, Zhou J, Yu J
Citation:
Nucleic Acids Res. 2013 Feb 17. [Epub ahead of print]
Epub:
Not Epub
Abstract:
miRNAs play important roles in many biological processes, including erythropoiesis. Although several miRNAs regulate erythroid...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhu Y, Wang D, Wang F, Li T, Dong L, Liu H, Ma Y, Jiang F, Yin H, Yan W, Luo M, Tang Z, Zhang G, Wang Q, Zhang J, Zhou J, Yu J. A comprehensive analysis of GATA-1-regulated miRNAs reveals miR-23a to be a positive modulator of erythropoiesis. Nucleic Acids Res. 2013 Feb 17. [Epub ahead of print].

A founder mutation in Vps37A causes autosomal recessive complex hereditary spastic paraparesis

Authors:
Zivony-Elboum Y, Westbroek W, Kfir N, Savitzki D, Shoval Y, Bloom A, Rod R, Khayat M, Gross B, Samri W, Cohen H, Sonkin V, Freidman T, Geiger D, Fattal-Valevski A, Anikster Y, Waters AM, Kleta R, Falik-Zaccai TC
Citation:
J Med Genet. 2012 Jun 20. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BackgroundMembers of two seemingly unrelated kindreds of Arab Moslem origin presented with pronounced early onset spastic...
Organism or Cell Type:
zebrafish
Citation Extract:
Zivony-Elboum Y, Westbroek W, Kfir N, Savitzki D, Shoval Y, Bloom A, Rod R, Khayat M, Gross B, Samri W, Cohen H, Sonkin V, Freidman T, Geiger D, Fattal-Valevski A, Anikster Y, Waters AM, Kleta R, Falik-Zaccai TC. A founder mutation in Vps37A causes autosomal recessive complex hereditary spastic paraparesis. J Med Genet. 2012 Jun 20. [Epub ahead of print].

A Novel Morpholino Oligomer Targeting ISS-N1 Improves Rescue of Severe SMA Transgenic Mice

Authors:
Zhou H, Janghra N, Mitrpant C, Dickinson R, Anthony K, Price L, Eperon I, Wilton S, Morgan J, Muntoni F
Citation:
Hum Gene Ther. 2013;24(3):331–342
Epub:
Not Epub
Abstract:
In the search of the most efficacious antisense oligonucleotides (AO) aimed at inducing SMN2 exon 7 inclusion, we...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609631/
Delivery Method:
Vivo-Morpholino oligos and seperately bare Morpholino oligos
Organism or Cell Type:
mice, SMA model
Citation Extract:
Zhou H, Janghra N, Mitrpant C, Dickinson R, Anthony K, Price L, Eperon I, Wilton S, Morgan J, Muntoni F. A Novel Morpholino Oligomer Targeting ISS-N1 Improves Rescue of Severe SMA Transgenic Mice. Hum Gene Ther. 2013;24(3):331–342.

A role for the transcription intermediary factor 2 in zebrafish myelopoiesis

Authors:
Zhuravleva J, Solary E, Chluba J, Bastie JN, Delva L
Citation:
Exp Hematol. 2008 Feb 22; [Epub ahead of print]
Epub:
Not Epub
Abstract:
OBJECTIVE: TIF2 is fused with MOZ in the inv(8)(p11q13) acute myeloid leukemia. TIF2, member of the p160 family, is a histone...
Organism or Cell Type:
zebrafish
Citation Extract:
Zhuravleva J, Solary E, Chluba J, Bastie JN, Delva L. A role for the transcription intermediary factor 2 in zebrafish myelopoiesis. Exp Hematol. 2008 Feb 22; [Epub ahead of print].

Activation of germline-specific genes is required for limb regeneration in the Mexican axolotl

Authors:
Zhu W, Pao GM, Satoh A, Cummings G, Monaghan JR, Harkins TT, Bryant SV, Voss SR, Gardiner DM, Hunter T
Citation:
Dev Biol. 2012;[Epub ahead of print] doi:10.1016/j.ydbio.2012.07.021
Epub:
Not Epub
Abstract:
The capacity for tissue and organ regeneration in humans is dwarfed by comparison to that of salamanders. Emerging evidence...
Delivery Method:
Injection
Organism or Cell Type:
Ambystoma mexicanum (axolotl)
Citation Extract:
Zhu W, Pao GM, Satoh A, Cummings G, Monaghan JR, Harkins TT, Bryant SV, Voss SR, Gardiner DM, Hunter T. Activation of germline-specific genes is required for limb regeneration in the Mexican axolotl. Dev Biol. 2012;[Epub ahead of print] doi:10.1016/j.ydbio.2012.07.021.

ALDH2 mediates 5-nitrofuran activity in multiple species

Authors:
Zhou L, Ishizaki H, Spitzer M, Taylor KL, Temperley ND, Johnson SL, Brear P, Gautier P, Zeng Z, Mitchell A, Narayan V, McNeil EM, Melton DW, Smith TK, Tyers M, Westwood NJ, Patton EE.
Citation:
Chem Biol. 2012 Jul 27;19(7):883-92. doi: 10.1016/j.chembiol.2012.05.017.
Epub:
Not Epub
Abstract:
Understanding how drugs work in vivo is critical for drug design and for maximizing the potential of currently available drugs...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhou L, Ishizaki H, Spitzer M, Taylor KL, Temperley ND, Johnson SL, Brear P, Gautier P, Zeng Z, Mitchell A, Narayan V, McNeil EM, Melton DW, Smith TK, Tyers M, Westwood NJ, Patton EE. . ALDH2 mediates 5-nitrofuran activity in multiple species. Chem Biol. 2012 Jul 27;19(7):883-92. doi: 10.1016/j.chembiol.2012.05.017..

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