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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

BMP9 mutations cause a vascular-anomaly syndrome with phenotypic overlap with hereditary hemorrhagic telangiectasia

Authors:
Wooderchak-Donahue WL, McDonald J, O'Fallon B, Upton PD, Li W, Roman BL, Young S, Plant P, Fülöp GT, Langa C, Morrell NW, Botella LM, Bernabeu C, Stevenson DA, Runo JR, Bayrak-Toydemir P
Citation:
Am J Hum Genet. 2013 Sep 5;93(3):530-7. doi: 10.1016/j.ajhg.2013.07.004. Epub 2013 Aug 22
Epub:
Not Epub
Abstract:
Hereditary hemorrhagic telangiectasia (HHT), the most common inherited vascular disorder, is caused by mutations in genes...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wooderchak-Donahue WL, McDonald J, O'Fallon B, Upton PD, Li W, Roman BL, Young S, Plant P, Fülöp GT, Langa C, Morrell NW, Botella LM, Bernabeu C, Stevenson DA, Runo JR, Bayrak-Toydemir P. BMP9 mutations cause a vascular-anomaly syndrome with phenotypic overlap with hereditary hemorrhagic telangiectasia. Am J Hum Genet. 2013 Sep 5;93(3):530-7. doi: 10.1016/j.ajhg.2013.07.004. Epub 2013 Aug 22.

Snx3 regulates recycling of the transferrin receptor and iron assimilation

Authors:
Chen C, Garcia-Santos D, Ishikawa Y, Seguin A, Li L, Fegan KH, Hildick-Smith GJ, Shah DI, Cooney JD, Chen W, King MJ, Yien YY, Schultz IJ, Anderson H, Dalton AJ, Freedman ML, Kingsley PD, Palis J, Hattangadi SM, Lodish HF, Ward DM, Kaplan J, Maeda T, Ponka P, Paw BH
Citation:
Cell Metab. 2013 Mar 5;17(3):343-52. doi: 10.1016/j.cmet.2013.01.013. Epub 2013 Feb 14
Epub:
Not Epub
Abstract:
Sorting of endocytic ligands and receptors is critical for diverse cellular processes. The physiological significance of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen C, Garcia-Santos D, Ishikawa Y, Seguin A, Li L, Fegan KH, Hildick-Smith GJ, Shah DI, Cooney JD, Chen W, King MJ, Yien YY, Schultz IJ, Anderson H, Dalton AJ, Freedman ML, Kingsley PD, Palis J, Hattangadi SM, Lodish HF, Ward DM, Kaplan J, Maeda T, Ponka P, Paw BH. Snx3 regulates recycling of the transferrin receptor and iron assimilation. Cell Metab. 2013 Mar 5;17(3):343-52. doi: 10.1016/j.cmet.2013.01.013. Epub 2013 Feb 14.

What Can We Learn From Clinical Trials of Exon Skipping for DMD?

Authors:
Lu Q-l, Cirak S, Terence Partridge T
Citation:
Molec Ther Nucleic Acids. 2014;3:e152. doi:10.1038/mtna.2014.6
Epub:
Not Epub
Abstract:
No abstract - this is available as open access online.
Delivery Method:
i.v. infusion
Organism or Cell Type:
human
Citation Extract:
Lu Q-l, Cirak S, Terence Partridge T. What Can We Learn From Clinical Trials of Exon Skipping for DMD?. Molec Ther Nucleic Acids. 2014;3:e152. doi:10.1038/mtna.2014.6.

Immunophilin FKBP52 induces Tau-P301L filamentous assembly in vitro and modulates its activity in a model of tauopathy

Authors:
Giustiniani J, Chambraud B, Sardin E, Dounane O, Guillemeau K, Nakatani H, Paquet D, Kamah A, Landrieu I, Lippens G, Baulieu E-E, Tawk M
Citation:
PNAS USA. 2014;[Epub ahead of print] doi:10.1073/pnas.1402645111
Epub:
Yes
Abstract:
Growing evidence underlines the role attributed to abnormal forms of Tau in several neurodegenerative diseases known as...
Organism or Cell Type:
zebrafish
Citation Extract:
Giustiniani J, Chambraud B, Sardin E, Dounane O, Guillemeau K, Nakatani H, Paquet D, Kamah A, Landrieu I, Lippens G, Baulieu E-E, Tawk M. Immunophilin FKBP52 induces Tau-P301L filamentous assembly in vitro and modulates its activity in a model of tauopathy. PNAS USA. 2014;[Epub ahead of print] doi:10.1073/pnas.1402645111.

Multicellular Tumor Spheroids as a Model for Assessing Delivery of Oligonucleotides in Three Dimensions

Authors:
Carver K, Ming X, Juliano RL
Citation:
Mol Ther Nucleic Acids. 2014;3:e153. doi:10.1038/mtna.2014.5
Epub:
Not Epub
Abstract:
Oligonucleotides have shown promise in selectively manipulating gene expression in vitro, but that success has not translated...
Delivery Method:
peptide-linked
Organism or Cell Type:
culture: multicellular tumor spheroid
Citation Extract:
Carver K, Ming X, Juliano RL. Multicellular Tumor Spheroids as a Model for Assessing Delivery of Oligonucleotides in Three Dimensions. Mol Ther Nucleic Acids. 2014;3:e153. doi:10.1038/mtna.2014.5.

Mycobacterium abscessus cording prevents phagocytosis and promotes abscess formation

Authors:
Bernut A, Herrmann JL, Kissa K, Dubremetz JF, Gaillard JL, Lutfalla G, Kremer L
Citation:
Proc Natl Acad Sci U S A. 2014 Feb 24. [Epub ahead of print]
Epub:
Yes
Abstract:
Mycobacterium abscessus is a rapidly growing Mycobacterium causing a wide spectrum of clinical syndromes. It now is recognized...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bernut A, Herrmann JL, Kissa K, Dubremetz JF, Gaillard JL, Lutfalla G, Kremer L. Mycobacterium abscessus cording prevents phagocytosis and promotes abscess formation. Proc Natl Acad Sci U S A. 2014 Feb 24. [Epub ahead of print].

Tissue damage detection by osmotic surveillance

Authors:
Enyedi B, Kala S, Nikolich-Zugich T, Niethammer P
Citation:
Nat Cell Biol. 2013 Sep;15(9):1123-30. doi: 10.1038/ncb2818. Epub 2013 Aug 11
Epub:
Not Epub
Abstract:
How tissue damage is detected to induce inflammatory responses is unclear. Most studies have focused on damage signals released...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Enyedi B, Kala S, Nikolich-Zugich T, Niethammer P. Tissue damage detection by osmotic surveillance. Nat Cell Biol. 2013 Sep;15(9):1123-30. doi: 10.1038/ncb2818. Epub 2013 Aug 11.

Cyclic Nrarp mRNA expression is regulated by the somitic oscillator but Nrarp protein levels do not oscillate

Authors:
Wright D, Ferjentsik Z, Chong SW, Qiu X, Jiang YJ, Malapert P, Pourquié O, Van Hateren N, Wilson SA, Franco C, Gerhardt H, Dale JK, Maroto M
Citation:
Dev Dyn. 2009 Dec;238(12):3043-55. doi: 10.1002/dvdy.22139
Epub:
Not Epub
Abstract:
Somites are formed progressively from the presomitic mesoderm (PSM) in a highly regulated process according to a strict...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wright D, Ferjentsik Z, Chong SW, Qiu X, Jiang YJ, Malapert P, Pourquié O, Van Hateren N, Wilson SA, Franco C, Gerhardt H, Dale JK, Maroto M. Cyclic Nrarp mRNA expression is regulated by the somitic oscillator but Nrarp protein levels do not oscillate. Dev Dyn. 2009 Dec;238(12):3043-55. doi: 10.1002/dvdy.22139.

Epiblast integrity requires CLASP and Dystroglycan-mediated microtubule anchoring to the basal cortex

Authors:
Nakaya Y, Sukowati EW, Sheng G
Citation:
J Cell Biol. 2013 Aug 19;202(4):637-51. doi: 10.1083/jcb.201302075. Epub 2013 Aug 12
Epub:
Not Epub
Abstract:
Amniote epiblast cells differentiate into mesoderm and endoderm lineages during gastrulation through a process called...
Delivery Method:
microinjection
Organism or Cell Type:
chick
Citation Extract:
Nakaya Y, Sukowati EW, Sheng G. Epiblast integrity requires CLASP and Dystroglycan-mediated microtubule anchoring to the basal cortex. J Cell Biol. 2013 Aug 19;202(4):637-51. doi: 10.1083/jcb.201302075. Epub 2013 Aug 12.

Impaired angiogenesis and tumor development by inhibition of the mitotic kinesin Eg5

Authors:
Exertier P, Javerzat S, Wang B, Franco M, Herbert J, Platonova N, Winandy M, Pujol N, Nivelles O, Ormenese S, Godard V, Becker J, Bicknell R, Pineau R, Wilting J, Bikfalvi A, Hagedorn M
Citation:
Oncotarget. 2013 Dec;4(12):2302-16
Epub:
Not Epub
Abstract:
Kinesin motor proteins exert essential cellular functions in all eukaryotes. They control mitosis, migration and intracellular...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Exertier P, Javerzat S, Wang B, Franco M, Herbert J, Platonova N, Winandy M, Pujol N, Nivelles O, Ormenese S, Godard V, Becker J, Bicknell R, Pineau R, Wilting J, Bikfalvi A, Hagedorn M. Impaired angiogenesis and tumor development by inhibition of the mitotic kinesin Eg5. Oncotarget. 2013 Dec;4(12):2302-16.

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