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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Functional characterization of Prickle2 and BBS7 identify overlapping phenotypes yet distinct mechanisms
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Citation:
Dev Biol. 2014 Jun 2. pii: S0012-1606(14)00276-0. doi: 10.1016/j.ydbio.2014.05.020. [Epub ahead of print] Epub:
Yes Abstract:
Ciliopathies are genetic disorders that are caused by dysfunctional cilia and affect multiple organs. One type of ciliopathy,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mei X, Westfall TA, Zhang Q, Sheffield VC, Bassuk AG, Slusarski DC. Functional characterization of Prickle2 and BBS7 identify overlapping phenotypes yet distinct mechanisms. Dev Biol. 2014 Jun 2. pii: S0012-1606(14)00276-0. doi: 10.1016/j.ydbio.2014.05.020. [Epub ahead of print]. |
RNAi-Mediated Gene silencing in Zebrafish Triggered by Convergent Transcription
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Citation:
Sci Rep. 2014 Jun 9;4:5222. doi: 10.1038/srep05222 Epub:
Not Epub Abstract:
RNAi based strategies to induce gene silencing are commonly employed in numerous model organisms but have not been extensively... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Andrews OE, Cha DJ, Wei C, Patton JG. RNAi-Mediated Gene silencing in Zebrafish Triggered by Convergent Transcription. Sci Rep. 2014 Jun 9;4:5222. doi: 10.1038/srep05222. |
Transcriptome analysis of Rpl11-deficient zebrafish model of Diamond-Blackfan Anemia
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Citation:
Genomics Data. 2014;[Epub ahead of print] doi:10.1016/j.gdata.2014.06.008 Epub:
Not Epub Abstract:
To comprehensively reflect the roles of Rpl11 on the transcriptome of zebrafish model of Diamond-Blackfan Anemia (DBA), we... Organism or Cell Type:
zebrafish Citation Extract: Zhang Z, Jia H, Zhang Q, Wan Y, Song B, Jia Q, Liu H, Zhu X, Fang A. Transcriptome analysis of Rpl11-deficient zebrafish model of Diamond-Blackfan Anemia. Genomics Data. 2014;[Epub ahead of print] doi:10.1016/j.gdata.2014.06.008. |
Left-Right Organizer Flow Dynamics: How Much Cilia Activity Reliably Yields Laterality?
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Citation:
Dev Cell. 2014 Jun 11. pii: S1534-5807(14)00277-9. doi: 10.1016/j.devcel.2014.04.030. [Epub ahead of print] Epub:
Not Epub Abstract:
Internal organs are asymmetrically positioned inside the body. Embryonic motile cilia play an essential role in this process by... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sampaio P, Ferreira RR, Guerrero A, Pintado P, Tavares B, Amaro J, Smith AA, Montenegro-Johnson T, Smith DJ, Lopes SS. Left-Right Organizer Flow Dynamics: How Much Cilia Activity Reliably Yields Laterality?. Dev Cell. 2014 Jun 11. pii: S1534-5807(14)00277-9. doi: 10.1016/j.devcel.2014.04.030. [Epub ahead of print]. |
The Evolution and Appearance of C3 Duplications in Fish Originate an Exclusive Teleost c3 Gene Form with Anti-Inflammatory Activity
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Citation:
PLoS ONE. 2014;9(6):e99673. doi:10.1371/journal.pone.0099673 Epub:
Not Epub Abstract:
The complement system acts as a first line of defense and promotes organism homeostasis by modulating the fates of diverse... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Forn-Cuní G, Reis ES, Dios S, Posada D, Lambris JD, Figueras A, Novoa B. The Evolution and Appearance of C3 Duplications in Fish Originate an Exclusive Teleost c3 Gene Form with Anti-Inflammatory Activity. PLoS ONE. 2014;9(6):e99673. doi:10.1371/journal.pone.0099673. |
tRNA synthetase counteracts c-Myc to develop functional vasculature
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Citation:
eLife. 2014;3:e02349 doi:10.7554/eLife.02349#sthash.RGoSMvJd.dpuf Epub:
Not Epub Abstract:
Recent studies suggested an essential role for seryl-tRNA synthetase (SerRS) in vascular development. This role is specific to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Shi Y, Xu X, Zhang Q, Fu G, Mo Z, Wang GS, Kishi S, Yang X-L. tRNA synthetase counteracts c-Myc to develop functional vasculature. eLife. 2014;3:e02349 doi:10.7554/eLife.02349#sthash.RGoSMvJd.dpuf. |
Pharmacology of a central nervous system delivered 2'-o-methoxyethyl-modified survival of motor neuron splicing oligonucleotide in mice and nonhuman primates
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Citation:
J Pharmacol Exp Ther. 2014 Jul;350(1):46-55. doi: 10.1124/jpet.113.212407. Epub 2014 Apr 30 Epub:
Not Epub Abstract:
Spinal muscular atrophy (SMA) is a debilitating neuromuscular disease caused by the loss of survival of motor neuron (SMN)... Delivery Method:
intracerebroventricular injection Organism or Cell Type:
mice Citation Extract: Rigo F, Chun SJ, Norris DA, Hung G, Lee S, Matson J, Fey RA, Gaus H, Hua Y, Grundy JS, Krainer AR, Henry SP, Bennett CF.. Pharmacology of a central nervous system delivered 2'-o-methoxyethyl-modified survival of motor neuron splicing oligonucleotide in mice and nonhuman primates. J Pharmacol Exp Ther. 2014 Jul;350(1):46-55. doi: 10.1124/jpet.113.212407. Epub 2014 Apr 30. |
Ptena, but not Ptenb, reduces regeneration after spinal cord injury in adult zebrafish
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Citation:
Exp Neurol. 2014 Jun 11. pii: S0014-4886(14)00193-9. doi: 10.1016/j.expneurol.2014.06.006. [Epub ahead of print] Epub:
Yes Abstract:
Based on the observation that the tumor suppressor gene PTEN (phosphatase and tensin homolog) reduces regeneration after spinal... Organism or Cell Type:
zebrafish Citation Extract: Liu D, Yu Y, Schachner M. Ptena, but not Ptenb, reduces regeneration after spinal cord injury in adult zebrafish. Exp Neurol. 2014 Jun 11. pii: S0014-4886(14)00193-9. doi: 10.1016/j.expneurol.2014.06.006. [Epub ahead of print]. |
Ror2 Receptor Mediates Wnt11 Signaling and Affects Convergence and Extension Movements in Zebrafish
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Citation:
J Biol Chem. 2014 Jun 13. pii: jbc.M114.586099. [Epub ahead of print] Epub:
Not Epub Abstract:
The receptor tyrosine kinase Ror2 acts as an alternative receptor or coreceptor for Wnt5a and mediates Wnt5a-induced convergent... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bai Y, Tan X, Zhang H, Liu C, Zhao B, Li Y, Lu L, Liu Y, Zhou J. Ror2 Receptor Mediates Wnt11 Signaling and Affects Convergence and Extension Movements in Zebrafish. J Biol Chem. 2014 Jun 13. pii: jbc.M114.586099. [Epub ahead of print]. |
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders
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Citation:
Nat Genet. 2013 Jun;45(6):621-31. doi: 10.1038/ng.2610. Epub 2013 Apr 14 Epub:
Not Epub Abstract:
Elevated resting heart rate is associated with greater risk of cardiovascular disease and mortality. In a 2-stage meta-analysis... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: den Hoed M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, Nolte IM, Segrè AV, Holm H, Handsaker RE, Westra HJ, Johnson T, Isaacs A, Yang J, Lundby A, Zhao JH, Kim YJ, Go MJ, Almgren P, Bochud M, Boucher G, Cornelis MC, Gudbjartsson D, Hadley D, (authors deleted - database limit exceeded) Global BPgen Consortium; CARDIoGRAM Consortium, Erdmann J, Thompson JR; PR GWAS Consortium, Pfeufer A; QRS GWAS Consortium, Sotoodehnia N; QT-IGC Consortium, Newton-Cheh C; CHARGE-AF Consortium, Ellinor PT, Stricker BH, Metspalu A, Perola M, Beckmann JS, Smith GD, Stefansson K, Wareham NJ, Munroe PB, Sibon OC, Milan DJ, Snieder H, Samani NJ, Loos RJ. Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet. 2013 Jun;45(6):621-31. doi: 10.1038/ng.2610. Epub 2013 Apr 14. |