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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

A feedback loop between the liver-enriched transcription factor network and miR-122 controls hepatocyte differentiation

Authors:
Laudadio I, Manfroid I, Achouri Y, Schmidt D, Wilson MD, Cordi S, Thorrez L, Knoops L, Jacquemin P, Schuit F, Pierreux CE, Odom DT, Peers B, Lemaigre FP
Citation:
Gastroenterology. 2012 Jan;142(1):119-29. doi: 10.1053/j.gastro.2011.09.001. Epub 2011 Sep 12
Epub:
Not Epub
Abstract:
BACKGROUND & AIMS: Hepatocyte differentiation is controlled by liver-enriched transcription factors (LETFs). We...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Laudadio I, Manfroid I, Achouri Y, Schmidt D, Wilson MD, Cordi S, Thorrez L, Knoops L, Jacquemin P, Schuit F, Pierreux CE, Odom DT, Peers B, Lemaigre FP. A feedback loop between the liver-enriched transcription factor network and miR-122 controls hepatocyte differentiation. Gastroenterology. 2012 Jan;142(1):119-29. doi: 10.1053/j.gastro.2011.09.001. Epub 2011 Sep 12.

Cell communication with the neural plate is required for induction of neural markers by BMP inhibition: evidence for homeogenetic induction and implications for Xenopus animal cap and chick explant assays

Authors:
Linker C, De Almeida I, Papanayotou C, Stower M, Sabado V, Ghorani E, Streit A, Mayor R, Stern CD
Citation:
Dev Biol. 2009 Mar 15;327(2):478-86. doi: 10.1016/j.ydbio.2008.12.034. Epub 2009 Jan 3
Epub:
Not Epub
Abstract:
In Xenopus, the animal cap is very sensitive to BMP antagonists, which result in neuralization. In chick, however, only cells...
Delivery Method:
electroporation
Organism or Cell Type:
chick
Citation Extract:
Linker C, De Almeida I, Papanayotou C, Stower M, Sabado V, Ghorani E, Streit A, Mayor R, Stern CD. Cell communication with the neural plate is required for induction of neural markers by BMP inhibition: evidence for homeogenetic induction and implications for Xenopus animal cap and chick explant assays. Dev Biol. 2009 Mar 15;327(2):478-86. doi: 10.1016/j.ydbio.2008.12.034. Epub 2009 Jan 3.

Identification and functional analysis of the primary pantothenate transporter, PfPAT, of the human malaria parasite Plasmodium falciparum

Authors:
Augagneur Y, Jaubert L, Schiavoni M, Pachikara N, Garg A, Usmani-Brown S, Wesolowski D, Zeller S, Ghosal A, Cornillot E, Said HM, Kumar P, Altman S, Ben Mamoun C
Citation:
J Biol Chem. 2013 Jul 12;288(28):20558-67. doi: 10.1074/jbc.M113.482992. Epub 2013 May 31
Epub:
Not Epub
Abstract:
The human malaria parasite Plasmodium falciparum is absolutely dependent on the acquisition of host pantothenate for its...
Delivery Method:
peptide-coupled
Organism or Cell Type:
Plasmodium falciparum
Citation Extract:
Augagneur Y, Jaubert L, Schiavoni M, Pachikara N, Garg A, Usmani-Brown S, Wesolowski D, Zeller S, Ghosal A, Cornillot E, Said HM, Kumar P, Altman S, Ben Mamoun C. Identification and functional analysis of the primary pantothenate transporter, PfPAT, of the human malaria parasite Plasmodium falciparum. J Biol Chem. 2013 Jul 12;288(28):20558-67. doi: 10.1074/jbc.M113.482992. Epub 2013 May 31.

Modular Evolution of DNA Binding Preference of a Tbrain Transcription Factor Provides a Mechanism for Modifying Gene Regulatory Networks

Authors:
Cheatle Jarvela AM, Brubaker L, Vedenko A, Gupta A, Armitage BA, Bulyk ML, Hinman VF
Citation:
Mol Biol Evol. 2014 Jul 12. pii: msu213. [Epub ahead of print]
Epub:
Yes
Abstract:
Gene regulatory networks (GRNs) describe the progression of transcriptional states that take a single-celled zygote to a...
Delivery Method:
microinjection
Organism or Cell Type:
Patiria miniata (sea star)
Citation Extract:
Cheatle Jarvela AM, Brubaker L, Vedenko A, Gupta A, Armitage BA, Bulyk ML, Hinman VF. Modular Evolution of DNA Binding Preference of a Tbrain Transcription Factor Provides a Mechanism for Modifying Gene Regulatory Networks. Mol Biol Evol. 2014 Jul 12. pii: msu213. [Epub ahead of print].

Maternally-Inherited npm2 mRNA Is Crucial for Egg Developmental Competence in Zebrafish

Authors:
Bouleau A, Desvignes T, Traverso JM, Nguyen T, Chesnel F, Fauvel C, Bobe J
Citation:
Biol Reprod. 2014 Jul 9. pii: biolreprod.114.119925. [Epub ahead of print]
Epub:
Yes
Abstract:
The molecular mechanisms underlying and determining egg developmental competence remain poorly understood in vertebrates....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bouleau A, Desvignes T, Traverso JM, Nguyen T, Chesnel F, Fauvel C, Bobe J. Maternally-Inherited npm2 mRNA Is Crucial for Egg Developmental Competence in Zebrafish. Biol Reprod. 2014 Jul 9. pii: biolreprod.114.119925. [Epub ahead of print].

Alternative splicing of Wilms tumor suppressor 1 (Wt1) exon 4 results in protein isoforms with different functions

Authors:
Schnerwitzki D, Perner B, Hoppe B, Pietsch S, Mehringer R, Hänel F, Englert C
Citation:
Dev Biol. 2014 Jul 8. pii: S0012-1606(14)00322-4. doi: 10.1016/j.ydbio.2014.06.026. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The Wilms tumor suppressor gene Wt1 encodes a zinc finger transcription factor that is essential for development of multiple...
Organism or Cell Type:
zebrafish
Citation Extract:
Schnerwitzki D, Perner B, Hoppe B, Pietsch S, Mehringer R, Hänel F, Englert C. Alternative splicing of Wilms tumor suppressor 1 (Wt1) exon 4 results in protein isoforms with different functions. Dev Biol. 2014 Jul 8. pii: S0012-1606(14)00322-4. doi: 10.1016/j.ydbio.2014.06.026. [Epub ahead of print].

Fam40b is required for lineage commitment of murine embryonic stem cells

Authors:
Wagh V, Doss MX, Sabour D, Niemann R, Meganathan K, Jagtap S, Gaspar JA, Ardestani MA, Papadopoulos S, Gajewski M, Winkler J, Hescheler J, Sachinidis A
Citation:
Cell Death Dis. 2014 Jul 10;5:e1320. doi: 10.1038/cddis.2014.273
Epub:
Not Epub
Abstract:
FAM40B (STRIP2) is a member of the striatin-interacting phosphatase and kinase (STRIPAK) complex that is involved in the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wagh V, Doss MX, Sabour D, Niemann R, Meganathan K, Jagtap S, Gaspar JA, Ardestani MA, Papadopoulos S, Gajewski M, Winkler J, Hescheler J, Sachinidis A. Fam40b is required for lineage commitment of murine embryonic stem cells. Cell Death Dis. 2014 Jul 10;5:e1320. doi: 10.1038/cddis.2014.273.

Destabilizing LSD1 by Jade-2 Promotes Neurogenesis: An Antibraking System in Neural Development

Authors:
Han X, Gui B, Xiong C, Zhao L, Liang J, Sun L, Yang X, Yu W, Si W, Yan R, Yi X, Zhang D, Li W, Li L, Yang J, Wang Y, Sun YE, Zhang D, Meng A, Shang Y
Citation:
Molec Cell. 2014;[Epub ahead of print] doi:10.1016/j.molcel.2014.06.006
Epub:
Yes
Abstract:
Histone H3K4 demethylase LSD1 plays an important role in stem cell biology, especially in the maintenance of the silencing of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Han X, Gui B, Xiong C, Zhao L, Liang J, Sun L, Yang X, Yu W, Si W, Yan R, Yi X, Zhang D, Li W, Li L, Yang J, Wang Y, Sun YE, Zhang D, Meng A, Shang Y. Destabilizing LSD1 by Jade-2 Promotes Neurogenesis: An Antibraking System in Neural Development. Molec Cell. 2014;[Epub ahead of print] doi:10.1016/j.molcel.2014.06.006.

Occupancy of tissue-specific cis-regulatory modules by Otx2 and TLE/Groucho for embryonic head specification

Authors:
Yasuoka Y, Suzuki Y, Takahashi S, Someya H, Sudou N, Haramoto Y, Cho KW, Asashima M, Sugano S, Taira M
Citation:
Nat Commun. 2014 Jul 9;5:4322. doi: 10.1038/ncomms5322
Epub:
Not Epub
Abstract:
Head specification by the head-selector gene, orthodenticle (otx), is highly conserved among bilaterian lineages. However, the...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Yasuoka Y, Suzuki Y, Takahashi S, Someya H, Sudou N, Haramoto Y, Cho KW, Asashima M, Sugano S, Taira M. Occupancy of tissue-specific cis-regulatory modules by Otx2 and TLE/Groucho for embryonic head specification. Nat Commun. 2014 Jul 9;5:4322. doi: 10.1038/ncomms5322.

Disruption of the Basal Body Protein POC1B Results in Autosomal-Recessive Cone-Rod Dystrophy

Authors:
Roosing S, Lamers IJC, de Vrieze E, van den Born LI, Lambertus S, Arts HH, POC1B Study Group, Peters TA, Hoyng CB, Kremer H, Hetterschijt L, Letteboer SJF, van Wijk E, Roepman R, den Hollander AI, Cremers FPM
Citation:
Am J Hum Genet. 2014;[Epub ahead of print] doi:10.1016/j.ajhg.2014.06.012
Epub:
Not Epub
Abstract:
Exome sequencing revealed a homozygous missense mutation (c.317C>G [p.Arg106Pro]) in POC1B, encoding POC1 centriolar protein...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Roosing S, Lamers IJC, de Vrieze E, van den Born LI, Lambertus S, Arts HH, POC1B Study Group, Peters TA, Hoyng CB, Kremer H, Hetterschijt L, Letteboer SJF, van Wijk E, Roepman R, den Hollander AI, Cremers FPM. Disruption of the Basal Body Protein POC1B Results in Autosomal-Recessive Cone-Rod Dystrophy. Am J Hum Genet. 2014;[Epub ahead of print] doi:10.1016/j.ajhg.2014.06.012.

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