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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
High-throughput screening identifies small molecules that enhance the pharmacological effects of oligonucleotides
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Citation:
Nucl Acids Res. 2015;[Epub ahead of print] doi:10.1093/nar/gkv060 Epub:
Yes Abstract:
The therapeutic use of antisense and siRNA oligonucleotides has been constrained by the limited ability of these membrane-... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture: A375 melanoma cells Citation Extract: Yang B, Ming X, Cao C, Laing B, Yuan A, Porter MA, Hull-Ryde EA, Maddry J, Suto M, Janzen WP, Juliano RL. High-throughput screening identifies small molecules that enhance the pharmacological effects of oligonucleotides. Nucl Acids Res. 2015;[Epub ahead of print] doi:10.1093/nar/gkv060 . |
PTPMT1 Inhibition Lowers Glucose through Succinate Dehydrogenase Phosphorylation
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Citation:
Cell Rep. 2015;[Epub ahead of print] doi:/10.1016/j.celrep.2015.01.010 Epub:
Yes Abstract:
Virtually all organisms seek to maximize fitness by matching fuel availability with energy expenditure. In vertebrates, glucose... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Nath AK, Ryu JH, Jin YN, Roberts LD, Dejam A, Gerszten RE, Peterson RT. PTPMT1 Inhibition Lowers Glucose through Succinate Dehydrogenase Phosphorylation. Cell Rep. 2015;[Epub ahead of print] doi:/10.1016/j.celrep.2015.01.010. |
cnrip1 is a regulator of eye and neural development in Xenopus laevis
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Citation:
Genes Cells. 2015 Feb 5. doi: 10.1111/gtc.12225. [Epub ahead of print] Epub:
Yes Abstract:
Cannabinoid receptor interacting protein 1 (CNRIP1), which has been originally identified as the binding partner of cannabinoid... Organism or Cell Type:
Xenopus laevis Citation Extract: Zheng X, Suzuki T, Takahashi C, Nishida E, Kusakabe M. cnrip1 is a regulator of eye and neural development in Xenopus laevis. Genes Cells. 2015 Feb 5. doi: 10.1111/gtc.12225. [Epub ahead of print]. |
FGF signalling restricts haematopoietic stem cell specification via modulation of the BMP pathway
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Citation:
Nat Commun. 2014 Nov 27;5:5588. doi: 10.1038/ncomms6588 Epub:
Not Epub Abstract:
Haematopoietic stem cells (HSCs) are produced during embryogenesis from the floor of the dorsal aorta. The localization of HSCs... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pouget C, Peterkin T, Simões FC, Lee Y, Traver D, Patient R. FGF signalling restricts haematopoietic stem cell specification via modulation of the BMP pathway. Nat Commun. 2014 Nov 27;5:5588. doi: 10.1038/ncomms6588. |
Disruption of CLPB is associated with congenital microcephaly, severe encephalopathy and 3-methylglutaconic aciduria
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Citation:
J Med Genet. 2015 Feb 3. pii: jmedgenet-2014-102952. doi: 10.1136/jmedgenet-2014-102952. [Epub ahead of print] Epub:
Not Epub Abstract:
BACKGROUND: The heterogeneous group of 3-methylglutaconic aciduria disorders includes several inborn errors of metabolism that... Organism or Cell Type:
zebrafish Citation Extract: Capo-Chichi JM, Boissel S, Brustein E, Pickles S, Fallet-Bianco C, Nassif C, Patry L, Dobrzeniecka S, Liao M, Labuda D, Samuels ME, Hamdan FF, Velde CV, Rouleau GA, Drapeau P, Michaud JL. Disruption of CLPB is associated with congenital microcephaly, severe encephalopathy and 3-methylglutaconic aciduria. J Med Genet. 2015 Feb 3. pii: jmedgenet-2014-102952. doi: 10.1136/jmedgenet-2014-102952. [Epub ahead of print]. |
A comparison of two cellular delivery mechanisms for small interfering RNA
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Citation:
Physiol Rep. 2015 Feb 3;3(2). pii: e12286. doi: 10.14814/phy2.12286. Print 2015 Feb 1 Epub:
Not Epub Abstract:
Cellular delivery of small interfering RNAs to target cells of a tissue has the potential to travel by two intercellular... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: HeLaCx43 & HEK293 Citation Extract: Valiunas V, Wang HZ, Li L, Gordon C, Valiuniene L, Cohen IS, Brink PR. A comparison of two cellular delivery mechanisms for small interfering RNA. Physiol Rep. 2015 Feb 3;3(2). pii: e12286. doi: 10.14814/phy2.12286. Print 2015 Feb 1. |
Disruption of KATP channel expression in skeletal muscle by targeted oligonucleotide delivery promotes activity-linked thermogenesis
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Citation:
Mol Ther. 2015 Apr;23(4):707-16. doi: 10.1038/mt.2015.21. Epub 2015 Feb 4. Epub:
Yes Abstract:
Despite the medical, social and economic impact of obesity, only a few therapeutic options, focused largely on reducing caloric... Delivery Method:
Vivo-Morpholino Citation Extract: Koganti SR, Zhu Z, Subbotina E, Gao Z, Sierra A, Proenza M, Yang L, Alekseev A, Hodgson-Zingman D, Zingman L. Disruption of KATP channel expression in skeletal muscle by targeted oligonucleotide delivery promotes activity-linked thermogenesis. Mol Ther. 2015 Apr;23(4):707-16. doi: 10.1038/mt.2015.21. Epub 2015 Feb 4.. |
Long-Term Efficacy of Systemic Multiexon Skipping Targeting Dystrophin Exons 45-55 With a Cocktail of Vivo-Morpholinos in Mdx52 Mice
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Citation:
Mol Ther Nucleic Acids. 2015 Feb 3;4:e225. doi: 10.1038/mtna.2014.76 Epub:
Not Epub Abstract:
Antisense-mediated exon skipping, which can restore the reading frame, is a most promising therapeutic approach for Duchenne... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mdx52 mice Citation Extract: Echigoya Y, Aoki Y, Miskew B, Panesar D, Touznik A, Nagata T, Tanihata J, Nakamura A, Nagaraju K, Yokota T. Long-Term Efficacy of Systemic Multiexon Skipping Targeting Dystrophin Exons 45-55 With a Cocktail of Vivo-Morpholinos in Mdx52 Mice. Mol Ther Nucleic Acids. 2015 Feb 3;4:e225. doi: 10.1038/mtna.2014.76. |
NAD kinase controls animal NADP biosynthesis and is modulated via evolutionarily divergent calmodulin-dependent mechanisms
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Citation:
Proc Natl Acad Sci U S A. 2015 Jan 20. pii: 201417290. [Epub ahead of print] Epub:
Yes Abstract:
Nicotinamide adenine dinucleotide phosphate (NADP) is a critical cofactor during metabolism, calcium signaling, and oxidative... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Love NR, Pollak N, Dölle C, Niere M, Chen Y, Oliveri P, Amaya E, Patel S, Ziegler M. NAD kinase controls animal NADP biosynthesis and is modulated via evolutionarily divergent calmodulin-dependent mechanisms. Proc Natl Acad Sci U S A. 2015 Jan 20. pii: 201417290. [Epub ahead of print]. |
Loss of wwox expression in zebrafish embryos causes edema and alters Ca2+ dynamics
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Citation:
PeerJ. 2015;3:e727 doi:10.7717/peerj.727 Epub:
Not Epub Abstract:
We investigated the role of the WW domain-containing oxidoreductase (wwox) gene in the embryonic development of zebrafish, with... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tsuruwaka Y, Konishi M, Shimada E. Loss of wwox expression in zebrafish embryos causes edema and alters Ca2+ dynamics. PeerJ. 2015;3:e727 doi:10.7717/peerj.727. |