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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
The TORC2 Component, Sin1, Controls Migration of Anterior Mesendoderm during Zebrafish Gastrulation
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Citation:
PLoS ONE. 2015;10(2):e0118474. doi:10.1371/journal.pone.0118474 Epub:
Not Epub Abstract:
TORC2 is a serine-threonine kinase complex conserved through evolution that recently emerged as a new regulator of actin... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dumortier JG, David NB. The TORC2 Component, Sin1, Controls Migration of Anterior Mesendoderm during Zebrafish Gastrulation. PLoS ONE. 2015;10(2):e0118474. doi:10.1371/journal.pone.0118474. |
Late Alk4/5/7 signaling is required for anterior skeletal patterning in sea urchin embryos
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Citation:
Development. 2015 Jan 29. pii: dev.114322. [Epub ahead of print] Epub:
Yes Abstract:
Skeletal patterning in the sea urchin embryo requires a conversation between the skeletogenic primary mesenchyme cells (PMCs)... Delivery Method:
microinjection Organism or Cell Type:
Lytechinus variegatus (sea urchin) Citation Extract: Piacentino ML, Ramachandran J, Bradham CA. Late Alk4/5/7 signaling is required for anterior skeletal patterning in sea urchin embryos. Development. 2015 Jan 29. pii: dev.114322. [Epub ahead of print]. |
Asymmetric inheritance of the apical domain and self-renewal of retinal ganglion cell progenitors depend on Anillin function
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Citation:
Development. 2015 Feb 5. pii: dev.118612. [Epub ahead of print] Epub:
Not Epub Abstract:
Divisions that generate one neuronal lineage-committed and one self-renewing cell maintain the balance of proliferation and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Paolini A, Duchemin AL, Albadri S, Patzel E, Bornhorst D, González Avalos P, Lemke S, Machate A, Brand M, Sel S, Di Donato V, Del Bene F, Zolessi FR, Ramialison M, Poggi L. Asymmetric inheritance of the apical domain and self-renewal of retinal ganglion cell progenitors depend on Anillin function. Development. 2015 Feb 5. pii: dev.118612. [Epub ahead of print]. |
P16 is an essential regulator of skeletogenesis in the sea urchin embryo
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Citation:
Dev Biol. 2005;283(2):384-96 Epub:
Not Epub Abstract:
The primary mesenchyme cells (PMCs) of the sea urchin embryo undergo a dramatic sequence of morphogenetic behaviors that... Delivery Method:
microinjection Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin) Citation Extract: Cheers MS, Ettensohn CA. P16 is an essential regulator of skeletogenesis in the sea urchin embryo. Dev Biol. 2005;283(2):384-96. |
A homozygous PDE6D mutation in Joubert syndrome impairs targeting of farnesylated INPP5E protein to the primary cilium
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Citation:
Hum Mutat. 2014 Jan;35(1):137-46 Epub:
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Joubert syndrome (JS) is characterized by a distinctive cerebellar structural defect, namely the << molar tooth sign... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Thomas S, Wright KJ, Le Corre S, Micalizzi A, Romani M, Abhyankar A, Saada J, Perrault I, Amiel J, Litzler J, Filhol E, Elkhartoufi N, Kwong M, Casanova JL, Boddaert N, Baehr W, Lyonnet S, Munnich A, Burglen L, Chassaing N, Encha-Ravazi F, Vekemans M, Gleeson JG, Valente EM, Jackson PK, Drummond IA, Saunier S, Attié-Bitach T. A homozygous PDE6D mutation in Joubert syndrome impairs targeting of farnesylated INPP5E protein to the primary cilium. Hum Mutat. 2014 Jan;35(1):137-46. |
Hedgehog signaling requires motile cilia in the sea urchin
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Citation:
Mol Biol Evol. 2014 Jan;31(1):18-22. doi: 10.1093/molbev/mst176. Epub 2013 Oct 11 Epub:
Not Epub Abstract:
A relatively small number of signaling pathways govern the early patterning processes of metazoan development. The... Delivery Method:
microinjection Organism or Cell Type:
Lytechinus variegatus (sea urchin) Citation Extract: Warner JF, McCarthy AM, Morris RL, McClay DR. Hedgehog signaling requires motile cilia in the sea urchin. Mol Biol Evol. 2014 Jan;31(1):18-22. doi: 10.1093/molbev/mst176. Epub 2013 Oct 11. |
Histone titration against the genome sets the DNA-to-cytoplasm threshold for the Xenopus midblastula transition
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Citation:
PNAS. 2015;[Epub ahead of print] doi:10.1073/pnas.1413990112 Epub:
Yes Abstract:
Embryos depend on maternally deposited RNA until zygotic transcription activates. In many species, genome activation coincides... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Amodeo AA, Jukam D, Straight AF, Skotheim JM. Histone titration against the genome sets the DNA-to-cytoplasm threshold for the Xenopus midblastula transition. PNAS. 2015;[Epub ahead of print] doi:10.1073/pnas.1413990112. |
A Distinct Mechanism of Vascular Lumen Formation in Xenopus Requires EGFL7
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Citation:
PLoS ONE. 2015;10(2): e0116086. doi:10.1371/journal.pone.0116086 Epub:
Not Epub Abstract:
During vertebrate blood vessel development, lumen formation is the critical process by which cords of endothelial cells... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Charpentier MS, Tandon P, Trincot CE, Koutleva EK, Conlon FL. A Distinct Mechanism of Vascular Lumen Formation in Xenopus Requires EGFL7. PLoS ONE. 2015;10(2): e0116086. doi:10.1371/journal.pone.0116086. |
DNA methyltransferase 1 functions through C/ebpa to maintain hematopoietic stem and progenitor cells in zebrafish
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Citation:
J Hematol Oncol. 2015;8:15. doi:10.1186/s13045-015-0115-7 Epub:
Not Epub Abstract:
Background DNA methyltransferase 1 (Dnmt1) regulates expression of many critical genes through maintaining parental DNA... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu X, Jia X, Yuan H, Ma K, Chen Y, Jin Y, Deng M, Pan W, Chen S, Chen Z, de The H, Zon LI, Zhou Y, Jun Zhou, Jun Zhu J. DNA methyltransferase 1 functions through C/ebpa to maintain hematopoietic stem and progenitor cells in zebrafish. J Hematol Oncol. 2015;8:15. doi:10.1186/s13045-015-0115-7. |
Evaluation of Zebrafish Kidney Function Using a Fluorescent Clearance Assay
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Citation:
J Vis Exp. 2015;96:e52540. doi:10.3791/52540 Epub:
Not Epub Abstract:
The zebrafish embryo offers a tractable model to study organogenesis and model human genetic disease. Despite its relative... Link:
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microinjection Organism or Cell Type:
zebrafish Citation Extract: Christou-Savina S, Beales PL, Osborn DPS. Evaluation of Zebrafish Kidney Function Using a Fluorescent Clearance Assay. J Vis Exp. 2015;96:e52540. doi:10.3791/52540. |