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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Notum Is Required for Neural and Head Induction via Wnt Deacylation, Oxidation, and Inactivation

Authors:
Zhang X, Cheong S-M, Amado NG, Reis AH, MacDonald BT, Zebisch M, Jones EY, Abreu JG, He X
Citation:
Dev Cell. 2015;32(6):719-30. doi:10.1016/j.devcel.2015.02.014
Epub:
Not Epub
Abstract:
Secreted Wnt morphogens are essential for embryogenesis and homeostasis and require a lipid/palmitoleoylate modification for...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Zhang X, Cheong S-M, Amado NG, Reis AH, MacDonald BT, Zebisch M, Jones EY, Abreu JG, He X. Notum Is Required for Neural and Head Induction via Wnt Deacylation, Oxidation, and Inactivation. Dev Cell. 2015;32(6):719-30. doi:10.1016/j.devcel.2015.02.014.

Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction

Authors:
Akizu N, Cantagrel V, Zaki MS, Al-Gazali L, Wang X, Rosti RO, Dikoglu E, Gelot AB, Rosti B, Vaux KK, Scott EM, Silhavy JL, Schroth J, Copeland B, Schaffer AE, Gordts PLSM, Esko JD, Buschman MD, Field SJ, Napolitano G, Abdel-Salam GM, Ozgul RK, Sagıroglu MS, Azam M, Ismail S, Aglan M, Selim L, Mahmoud IG, Abdel-Hadi S, Badawy AE, Sadek AA, Mojahedi F, Kayserili H, Masri A, Bastaki L, Temtamy S, Müller U, Desguerre I, Casanova J-L, Dursun A, Gunel M, Gabriel SB, de Lonlay P, Gleeson JG
Citation:
Nat Genet. 2015;[Epub ahead of print] doi:10.1038/ng.3256
Epub:
Yes
Abstract:
Pediatric-onset ataxias often present clinically as developmental delay and intellectual disability, with prominent cerebellar...
Organism or Cell Type:
zebrafish
Citation Extract:
Akizu N, Cantagrel V, Zaki MS, Al-Gazali L, Wang X, Rosti RO, Dikoglu E, Gelot AB, Rosti B, Vaux KK, Scott EM, Silhavy JL, Schroth J, Copeland B, Schaffer AE, Gordts PLSM, Esko JD, Buschman MD, Field SJ, Napolitano G, Abdel-Salam GM, Ozgul RK, Sagıroglu MS, Azam M, Ismail S, Aglan M, Selim L, Mahmoud IG, Abdel-Hadi S, Badawy AE, Sadek AA, Mojahedi F, Kayserili H, Masri A, Bastaki L, Temtamy S, Müller U, Desguerre I, Casanova J-L, Dursun A, Gunel M, Gabriel SB, de Lonlay P, Gleeson JG. Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction. Nat Genet. 2015;[Epub ahead of print] doi:10.1038/ng.3256.

Identification of Novel Long Noncoding RNAs Underlying Vertebrate Cardiovascular Development

Authors:
Kurian L, Aguirre A, Sancho-Martinez I, Benner C, Hishida T, Nguyen TB, Reddy P, Nivet E, Krause MN, Nelles DA, Esteban CR, Campistol JM, Yeo GW, Belmonte JCI
Citation:
Circulation. 2015;131:1278-1290. doi:10.1161/CIRCULATIONAHA.114.013303
Epub:
Not Epub
Abstract:
Background—Long noncoding RNAs (lncRNAs) have emerged as critical epigenetic regulators with important functions in development...
Organism or Cell Type:
zebrafish
Citation Extract:
Kurian L, Aguirre A, Sancho-Martinez I, Benner C, Hishida T, Nguyen TB, Reddy P, Nivet E, Krause MN, Nelles DA, Esteban CR, Campistol JM, Yeo GW, Belmonte JCI. Identification of Novel Long Noncoding RNAs Underlying Vertebrate Cardiovascular Development. Circulation. 2015;131:1278-1290. doi:10.1161/CIRCULATIONAHA.114.013303 .

The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin

Authors:
Epting D, Slanchev K, Boehlke C, Hoff S, Loges NT, Yasunaga T, Indorf L, Nestel S, Lienkamp SS, Omran H, Kuehn EW, Ronneberger O, Walz G, Kramer-Zucker A
Citation:
Development. 2015 Jan 1;142(1):174-84. doi: 10.1242/dev.112250
Epub:
Not Epub
Abstract:
Cilia are microtubule-based organelles that are present on most cells and are required for normal tissue development and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish & Xenopus
Citation Extract:
Epting D, Slanchev K, Boehlke C, Hoff S, Loges NT, Yasunaga T, Indorf L, Nestel S, Lienkamp SS, Omran H, Kuehn EW, Ronneberger O, Walz G, Kramer-Zucker A. The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin. Development. 2015 Jan 1;142(1):174-84. doi: 10.1242/dev.112250.

Knockdown of transcription factor forkhead box O3 (FOXO3) suppresses erythroid differentiation in human cells and zebrafish

Authors:
Wang H, Li Y, Wang S, Zhang Q, Zheng J, Yang Y, Qi H, Qu H, Zhang Z, Liu F, Fang X
Citation:
Biochem Biophys Res Commun. 2015 Apr 2. pii: S0006-291X(15)00594-X. doi: 10.1016/j.bbrc.2015.03.128. [Epub ahead of print]
Epub:
Yes
Abstract:
Our previous study on the dynamic transcriptomes activated during human erythropoiesis suggested that transcription factor...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang H, Li Y, Wang S, Zhang Q, Zheng J, Yang Y, Qi H, Qu H, Zhang Z, Liu F, Fang X. Knockdown of transcription factor forkhead box O3 (FOXO3) suppresses erythroid differentiation in human cells and zebrafish. Biochem Biophys Res Commun. 2015 Apr 2. pii: S0006-291X(15)00594-X. doi: 10.1016/j.bbrc.2015.03.128. [Epub ahead of print].

glucagon is essential for alpha cell transdifferentiation and beta cell neogenesis

Authors:
Ye L, Robertson MA, Hesselson D, Stainier DYR, Anderson RM
Citation:
Development. 2015;142:1407-17. doi:10.1242/dev.117911
Epub:
Not Epub
Abstract:
The interconversion of cell lineages via transdifferentiation is an adaptive mode of tissue regeneration and an appealing...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ye L, Robertson MA, Hesselson D, Stainier DYR, Anderson RM. glucagon is essential for alpha cell transdifferentiation and beta cell neogenesis. Development. 2015;142:1407-17. doi:10.1242/dev.117911.

EBV noncoding RNA binds nascent RNA to drive host PAX5 to viral DNA

Authors:
Lee N, Moss WN, Yario TA, Steitz JA
Citation:
Cell. 2015 Feb 12;160(4):607-18. doi: 10.1016/j.cell.2015.01.015. Epub 2015 Feb 5
Epub:
Not Epub
Abstract:
EBER2 is an abundant nuclear noncoding RNA expressed by the Epstein-Barr virus (EBV). Probing its possible chromatin...
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: BJAB-B1 cells
Citation Extract:
Lee N, Moss WN, Yario TA, Steitz JA. EBV noncoding RNA binds nascent RNA to drive host PAX5 to viral DNA. Cell. 2015 Feb 12;160(4):607-18. doi: 10.1016/j.cell.2015.01.015. Epub 2015 Feb 5.

WT1 targets Gas1 to maintain nephron progenitor cells by modulating FGF signals

Authors:
Kann M, Bae E, Lenz MO, Li L, Trannguyen B, Schumacher VA, Taglienti ME, Bordeianou L, Hartwig S, Rinschen MM, Schermer B, Benzing T, Fan CM, Kreidberg JA
Citation:
Development. 2015 Apr 1;142(7):1254-66. doi: 10.1242/dev.119735
Epub:
Not Epub
Abstract:
Development of the metanephric kidney depends on tightly regulated interplay between self-renewal and differentiation of a...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
organ culture: mouse kidney culture
Citation Extract:
Kann M, Bae E, Lenz MO, Li L, Trannguyen B, Schumacher VA, Taglienti ME, Bordeianou L, Hartwig S, Rinschen MM, Schermer B, Benzing T, Fan CM, Kreidberg JA. WT1 targets Gas1 to maintain nephron progenitor cells by modulating FGF signals. Development. 2015 Apr 1;142(7):1254-66. doi: 10.1242/dev.119735.

ERK7 regulates ciliogenesis by phosphorylating the actin regulator CapZIP in cooperation with Dishevelled

Authors:
Miyatake K, Kusakabe M, Takahashi C, Nishida E
Citation:
Nat Commun. 2015 Mar 31;6:6666. doi: 10.1038/ncomms7666
Epub:
Not Epub
Abstract:
Cilia are essential for embryogenesis and maintenance of homeostasis, but little is known about the signalling pathways that...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Miyatake K, Kusakabe M, Takahashi C, Nishida E. ERK7 regulates ciliogenesis by phosphorylating the actin regulator CapZIP in cooperation with Dishevelled. Nat Commun. 2015 Mar 31;6:6666. doi: 10.1038/ncomms7666.

HS3ST2 expression is critical for the abnormal phosphorylation of tau in Alzheimer’s disease-related tau pathology

Authors:
Sepulveda-Diaz JE, Naini SMA, Huynh MB, Ouidja MO, Yanicostas C, Chantepie S, Villares J, Lamari F, Jospin E, van Kuppevelt TH, Mensah-Nyagan AG, Raisman-Vozari R, Soussi-Yanicostas N, Papy-Garcia D
Citation:
Brain. 2015;[Epub ahead of print] doi:10.1093/brain/awv056
Epub:
Yes
Abstract:
Heparan sulphate (glucosamine) 3-O-sulphotransferase 2 (HS3ST2, also known as 3OST2) is an enzyme predominantly expressed in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sepulveda-Diaz JE, Naini SMA, Huynh MB, Ouidja MO, Yanicostas C, Chantepie S, Villares J, Lamari F, Jospin E, van Kuppevelt TH, Mensah-Nyagan AG, Raisman-Vozari R, Soussi-Yanicostas N, Papy-Garcia D. HS3ST2 expression is critical for the abnormal phosphorylation of tau in Alzheimer’s disease-related tau pathology. Brain. 2015;[Epub ahead of print] doi:10.1093/brain/awv056.

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