You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Function and regulation of TRPP2 ion channel revealed by a gain-of-function mutant

Authors:
Pavel MA, Lv C, Ng C, Yang L, Kashyap P, Lam C, Valentino V, Fung HY, Campbell T, Møller SG, Zenisek D, Holtzman NG, Yu Y
Citation:
PNAS. 2016;[Epub ahead of print]. doi:10.1073/pnas.1517066113
Epub:
Yes
Abstract:
Mutations in polycystin-1 and transient receptor potential polycystin 2 (TRPP2) account for almost all clinically identified...
Link:
http://www.pnas.org/content/early/2016/04/07/1517066113.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pavel MA, Lv C, Ng C, Yang L, Kashyap P, Lam C, Valentino V, Fung HY, Campbell T, Møller SG, Zenisek D, Holtzman NG, Yu Y. Function and regulation of TRPP2 ion channel revealed by a gain-of-function mutant. PNAS. 2016;[Epub ahead of print]. doi:10.1073/pnas.1517066113.

Electroporation of Embryonic Chick Eyes

Authors:
Luz-Madrigal A, Grajales-Esquivel E, Del Rio-Tsonis K
Citation:
Bio Protoc. 2015 Jun 20;5(12). pii: e1498
Epub:
Not Epub
Abstract:
The chick embryo has prevailed as one of the major models to study developmental biology, cell biology and regeneration. From...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819969/
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Luz-Madrigal A, Grajales-Esquivel E, Del Rio-Tsonis K. Electroporation of Embryonic Chick Eyes. Bio Protoc. 2015 Jun 20;5(12). pii: e1498.

Gonadotropin-releasing hormone stimulates biliary proliferation by paracrine/autocrine mechanisms

Authors:
Ray D, Han Y, Franchitto A, DeMorrow S, Meng F, Venter J, McMillin M, Kennedy L, Francis H, Onori P, Mancinelli R, Gaudio E, Alpini G, Glaser SS
Citation:
Am J Pathol. 2015 Apr;185(4):1061-72. doi: 10.1016/j.ajpath.2014.12.004
Epub:
Not Epub
Abstract:
During cholestatic liver disease, there is dysregulation in the balance between biliary growth and loss in bile duct-ligated (...
Link:
http://ajp.amjpathol.org/article/S0002-9440%2815%2900011-5/abstract
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Rat
Citation Extract:
Ray D, Han Y, Franchitto A, DeMorrow S, Meng F, Venter J, McMillin M, Kennedy L, Francis H, Onori P, Mancinelli R, Gaudio E, Alpini G, Glaser SS. Gonadotropin-releasing hormone stimulates biliary proliferation by paracrine/autocrine mechanisms. Am J Pathol. 2015 Apr;185(4):1061-72. doi: 10.1016/j.ajpath.2014.12.004.

RBBP4 regulates histone deacetylation and bipolar spindle assembly during oocyte maturation in the mouse

Authors:
Balboula AZ, Stein P, Schultz RM, Schindler K
Citation:
Biol Reprod. 2015 Apr;92(4):105. doi: 10.1095/biolreprod.115.128298. Epub 2015 Mar 18
Epub:
Not Epub
Abstract:
During meiosis I (MI) in oocytes, the maturation-associated decrease of histone acetylation is critical for normal meiotic...
Link:
http://www.biolreprod.org/content/92/4/105.abstract
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Balboula AZ, Stein P, Schultz RM, Schindler K. RBBP4 regulates histone deacetylation and bipolar spindle assembly during oocyte maturation in the mouse. Biol Reprod. 2015 Apr;92(4):105. doi: 10.1095/biolreprod.115.128298. Epub 2015 Mar 18.

miR-216a regulates snx5, a novel notch signaling pathway component, during zebrafish retinal development

Authors:
Olena AF, Rao MB, Thatcher EJ, Wu SY, Patton JG
Citation:
Dev Biol. 2015 Apr 1;400(1):72-81. doi: 10.1016/j.ydbio.2015.01.016. Epub 2015 Jan 31
Epub:
Not Epub
Abstract:
Precise regulation of Notch signaling is essential for normal vertebrate development. Mind bomb (Mib) is a ubiquitin ligase...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160615000366
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Olena AF, Rao MB, Thatcher EJ, Wu SY, Patton JG. miR-216a regulates snx5, a novel notch signaling pathway component, during zebrafish retinal development. Dev Biol. 2015 Apr 1;400(1):72-81. doi: 10.1016/j.ydbio.2015.01.016. Epub 2015 Jan 31.

Prdm12 specifies V1 interneurons through cross-repressive interactions with Dbx1 and Nkx6 genes in Xenopus

Authors:
Thélie A, Desiderio S, Hanotel J, Quigley I, Van Driessche B, Rodari A, Borromeo MD, Kricha S, Lahaye F, Croce J, Cerda-Moya G, Ordoño Fernandez J, Bolle B, Lewis KE, Sander M, Pierani A, Schubert M, Johnson JE, Kintner CR, Pieler T, Van Lint C, Henningfeld KA, Bellefroid EJ, Van Campenhout C
Citation:
Development. 2015 Oct 1;142(19):3416-28. doi: 10.1242/dev.121871
Epub:
Not Epub
Abstract:
V1 interneurons are inhibitory neurons that play an essential role in vertebrate locomotion. The molecular mechanisms...
Link:
http://dev.biologists.org/content/142/19/3416.long
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Thélie A, Desiderio S, Hanotel J, Quigley I, Van Driessche B, Rodari A, Borromeo MD, Kricha S, Lahaye F, Croce J, Cerda-Moya G, Ordoño Fernandez J, Bolle B, Lewis KE, Sander M, Pierani A, Schubert M, Johnson JE, Kintner CR, Pieler T, Van Lint C, Henningfeld KA, Bellefroid EJ, Van Campenhout C. Prdm12 specifies V1 interneurons through cross-repressive interactions with Dbx1 and Nkx6 genes in Xenopus. Development. 2015 Oct 1;142(19):3416-28. doi: 10.1242/dev.121871.

Control of vertebrate core planar cell polarity protein localization and dynamics by Prickle 2

Authors:
Butler MT, Wallingford JB
Citation:
Development. 2015 Oct 1;142(19):3429-39. doi: 10.1242/dev.121384. Epub 2015 Aug 20
Epub:
Not Epub
Abstract:
Planar cell polarity (PCP) is a ubiquitous property of animal tissues and is essential for morphogenesis and homeostasis. In...
Link:
http://dev.biologists.org/content/142/19/3429.long
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Butler MT, Wallingford JB. Control of vertebrate core planar cell polarity protein localization and dynamics by Prickle 2. Development. 2015 Oct 1;142(19):3429-39. doi: 10.1242/dev.121384. Epub 2015 Aug 20.

Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation

Authors:
Martinez NM, Agosto L, Qiu J, Mallory MJ, Gazzara MR, Barash Y, Fu XD, Lynch KW
Citation:
Genes Dev. 2015 Oct 1;29(19):2054-66. doi: 10.1101/gad.267245.115
Epub:
Not Epub
Abstract:
Alternative splicing is prevalent among genes encoding signaling molecules; however, the functional consequence of differential...
Link:
http://genesdev.cshlp.org/content/29/19/2054.long
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: Jurkat T cells
Citation Extract:
Martinez NM, Agosto L, Qiu J, Mallory MJ, Gazzara MR, Barash Y, Fu XD, Lynch KW. Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation. Genes Dev. 2015 Oct 1;29(19):2054-66. doi: 10.1101/gad.267245.115.

Endothelial cilia are essential for developmental vascular integrity in zebrafish

Authors:
Kallakuri S, Yu JA, Li J, Li Y, Weinstein BM, Nicoli S, Sun Z
Citation:
J Am Soc Nephrol. 2015 Apr;26(4):864-75. doi: 10.1681/ASN.2013121314. Epub 2014 Sep 11
Epub:
Not Epub
Abstract:
The cilium is a signaling platform of the vertebrate cell. It has a critical role in polycystic kidney disease and...
Link:
http://jasn.asnjournals.org/content/26/4/864.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kallakuri S, Yu JA, Li J, Li Y, Weinstein BM, Nicoli S, Sun Z. Endothelial cilia are essential for developmental vascular integrity in zebrafish. J Am Soc Nephrol. 2015 Apr;26(4):864-75. doi: 10.1681/ASN.2013121314. Epub 2014 Sep 11.

A novel missense mutation of Wilms' Tumor 1 causes autosomal dominant FSGS

Authors:
Hall G, Gbadegesin RA, Lavin P, Wu G, Liu Y, Oh EC, Wang L, Spurney RF, Eckel J, Lindsey T, Homstad A, Malone AF, Phelan PJ, Shaw A, Howell DN, Conlon PJ, Katsanis N, Winn MP
Citation:
J Am Soc Nephrol. 2015 Apr;26(4):831-43. doi: 10.1681/ASN.2013101053. Epub 2014 Aug 21
Epub:
Not Epub
Abstract:
FSGS is a clinical disorder characterized by focal scarring of the glomerular capillary tuft, podocyte injury, and nephrotic...
Link:
http://jasn.asnjournals.org/content/26/4/831.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hall G, Gbadegesin RA, Lavin P, Wu G, Liu Y, Oh EC, Wang L, Spurney RF, Eckel J, Lindsey T, Homstad A, Malone AF, Phelan PJ, Shaw A, Howell DN, Conlon PJ, Katsanis N, Winn MP. A novel missense mutation of Wilms' Tumor 1 causes autosomal dominant FSGS. J Am Soc Nephrol. 2015 Apr;26(4):831-43. doi: 10.1681/ASN.2013101053. Epub 2014 Aug 21.

Pages