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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Protective effect of prostacyclin against pre-cardiac edema caused by 2,3,7,8-tetrachlorodibenzo-p-dioxin and a thromboxane receptor agonist in developing zebrafish

Authors:
Nijoukubo D, Tanaka Y, Okuno Y, Yin G, Kitazawa T, Peterson RE, Kubota A, Teraoka H
Citation:
Chemosphere. 2016 May 9;156:111-117. doi: 10.1016/j.chemosphere.2016.04.107. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The role of prostaglandin pathways has been suggested in some toxicological responses to dioxins. Cyclooxygenase type 2b (COX2b...
Organism or Cell Type:
zebrafish
Citation Extract:
Nijoukubo D, Tanaka Y, Okuno Y, Yin G, Kitazawa T, Peterson RE, Kubota A, Teraoka H. Protective effect of prostacyclin against pre-cardiac edema caused by 2,3,7,8-tetrachlorodibenzo-p-dioxin and a thromboxane receptor agonist in developing zebrafish. Chemosphere. 2016 May 9;156:111-117. doi: 10.1016/j.chemosphere.2016.04.107. [Epub ahead of print].

Fluorescence Detection of DNA Based on Non-covalent π-π Stacking Interaction between 1-Pyrenebutanoic Acid and Hypericin

Authors:
Hu W, Zhang J, Kong J
Citation:
Anal Sci. 2016;32(5):523-7. doi: 10.2116/analsci.32.523
Epub:
Not Epub
Abstract:
Herein, we applied hypericin (Hyp) for the detection of DNA on streptavidin-functionalized magnetic beads (SA-MB) through non-...
Citation Extract:
Hu W, Zhang J, Kong J. Fluorescence Detection of DNA Based on Non-covalent π-π Stacking Interaction between 1-Pyrenebutanoic Acid and Hypericin. Anal Sci. 2016;32(5):523-7. doi: 10.2116/analsci.32.523.

Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures

Authors:
Wang X, Tucker NR, Rizki G, Mills R, Krijger PH, de Wit E, Subramanian V, Bartell E, Nguyen XX, Ye J, Leyton-Mange J, Dolmatova EV, van der Harst P, de Laat W, Ellinor PT, Newton-Cheh C, Milan DJ, Kellis M, Boyer LA
Citation:
Elife. 2016 May 10;5. pii: e10557. doi: 10.7554/eLife.10557
Epub:
Not Epub
Abstract:
Genetic variants identified by genome-wide association studies explain only a modest proportion of heritability, suggesting...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang X, Tucker NR, Rizki G, Mills R, Krijger PH, de Wit E, Subramanian V, Bartell E, Nguyen XX, Ye J, Leyton-Mange J, Dolmatova EV, van der Harst P, de Laat W, Ellinor PT, Newton-Cheh C, Milan DJ, Kellis M, Boyer LA. Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures. Elife. 2016 May 10;5. pii: e10557. doi: 10.7554/eLife.10557.

Histopathological Defects in Intestine in Severe Spinal Muscular Atrophy Mice Are Improved by Systemic Antisense Oligonucleotide Treatment

Authors:
Sintusek P, Catapano F, Angkathunkayul N, Marrosu E, Parson SH, Morgan JE, Muntoni F, Zhou H
Citation:
PLoS One. 2016 May 10;11(5):e0155032. doi: 10.1371/journal.pone.0155032. eCollection 2016
Epub:
Not Epub
Abstract:
Gastrointestinal (GI) defects, including gastroesophageal reflux, constipation and delayed gastric emptying, are common in...
Delivery Method:
subcutaneous (s.c.) injection
Organism or Cell Type:
mice
Citation Extract:
Sintusek P, Catapano F, Angkathunkayul N, Marrosu E, Parson SH, Morgan JE, Muntoni F, Zhou H. Histopathological Defects in Intestine in Severe Spinal Muscular Atrophy Mice Are Improved by Systemic Antisense Oligonucleotide Treatment. PLoS One. 2016 May 10;11(5):e0155032. doi: 10.1371/journal.pone.0155032. eCollection 2016.

Gene Expression Elucidates Functional Impact of Polygenic Risk for Schizophrenia

Authors:
Fromer M, Roussos P, Sieberts SK, Johnson JS, Kavanagh DH, Perumal TM, Ruderfer DM, Oh EC, Topol A, Shah HR, Klei LL, Kramer R, Pinto D, Gumus ZH, Cicek AE, Dang K, Browne A, Lu C, Xie L, Readhead B, Stahl EA, Parvisi M, Hamamsy T, Fullard JF, Wang Y-C, Mahajan MC, Derry JMJ, Dudley J, Hemby SE, Logsdon BA, Talbot K, Raj T, Bennett DA, De Jager PL, Zhu J, Zhang B, Sullivan PF, Chess A, Purcell SM, Shinobu LA, Mangravite LM, Toyoshiba H, Gur RE, Hahn C-G, Lewis DA, Haroutonian V, Peters MA, Lipska BK, Buxbaum JD, Schadt EE, Hira K, Roeder K, Brennand KJ, Katsanis N, Dominici E, Devlin B, Sklar P
Citation:
bioRxiv. 2016. doi:10.1101/052209
Epub:
Yes
Abstract:
Over 100 genetic loci harbor schizophrenia associated variants, yet how these common variants confer risk is uncertain. The...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fromer M, Roussos P, Sieberts SK, Johnson JS, Kavanagh DH, Perumal TM, Ruderfer DM, Oh EC, Topol A, Shah HR, Klei LL, Kramer R, Pinto D, Gumus ZH, Cicek AE, Dang K, Browne A, Lu C, Xie L, Readhead B, Stahl EA, Parvisi M, Hamamsy T, Fullard JF, Wang Y-C, Mahajan MC, Derry JMJ, Dudley J, Hemby SE, Logsdon BA, Talbot K, Raj T, Bennett DA, De Jager PL, Zhu J, Zhang B, Sullivan PF, Chess A, Purcell SM, Shinobu LA, Mangravite LM, Toyoshiba H, Gur RE, Hahn C-G, Lewis DA, Haroutonian V, Peters MA, Lipska BK, Buxbaum JD, Schadt EE, Hira K, Roeder K, Brennand KJ, Katsanis N, Dominici E, Devlin B, Sklar P. Gene Expression Elucidates Functional Impact of Polygenic Risk for Schizophrenia. bioRxiv. 2016. doi:10.1101/052209.

The Molecular Basis of Radial Intercalation during Tissue Spreading in Early Development

Authors:
Szabó A, Cobo I, Omara S, McLachlan S, Keller R, Mayor R
Citation:
Dev Cell. 2016;37(3):213-25. doi:10.1016/j.devcel.2016.04.008
Epub:
Not Epub
Abstract:
Radial intercalation is a fundamental process responsible for the thinning of multilayered tissues during large-scale...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Szabó A, Cobo I, Omara S, McLachlan S, Keller R, Mayor R . The Molecular Basis of Radial Intercalation during Tissue Spreading in Early Development. Dev Cell. 2016;37(3):213-25. doi:10.1016/j.devcel.2016.04.008.

History and Properties of Morpholino Antisense Oligos

Authors:
Summerton J
Citation:
J Drug Discov Develop and Deliv. 2016; 3(1): 1019
Epub:
Not Epub
Abstract:
This paper provides a very brief overview of the beginning of the antisense field, including the first antisense structural...
Citation Extract:
Summerton J. History and Properties of Morpholino Antisense Oligos. J Drug Discov Develop and Deliv. 2016; 3(1): 1019.

Custom Cocktail for Curing any Cancer: A Strategy for Destroying any Cancer without Harming the Patient

Authors:
Summerton J
Citation:
J Drug Discov Develop and Deliv. 2016; 3(1): 1020
Epub:
Not Epub
Abstract:
Drugs for curing any cancer must completely destroy a patient’s cancer without harming the patient. To avoid harming the...
Citation Extract:
Summerton J. Custom Cocktail for Curing any Cancer: A Strategy for Destroying any Cancer without Harming the Patient. J Drug Discov Develop and Deliv. 2016; 3(1): 1020.

MicroRNA-92a upholds Bmp signaling by targeting noggin3 during pharyngeal cartilage formation

Authors:
Ning G, Liu X, Dai M, Meng A, Wang Q.
Citation:
Dev Cell. 2013 Feb 11;24(3):283-95. doi: 10.1016/j.devcel.2012.12.016.
Epub:
Not Epub
Abstract:
Craniofacial malformations are common structural birth defects and usually associate with abnormal development of pharyngeal...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ning G, Liu X, Dai M, Meng A, Wang Q.. MicroRNA-92a upholds Bmp signaling by targeting noggin3 during pharyngeal cartilage formation. Dev Cell. 2013 Feb 11;24(3):283-95. doi: 10.1016/j.devcel.2012.12.016..

A Maternal System Initiating the Zygotic Developmental Program through Combinatorial Repression in the Ascidian Embryo

Authors:
Oda-Ishii I, Kubo A, Kari W, Suzuki N, Rothbächer U, Satou Y
Citation:
PLoS Genet. 2016;12(5):e1006045. doi:10.1371/journal.pgen.1006045
Epub:
Yes
Abstract:
Maternal factors initiate the zygotic developmental program in animal embryos. In embryos of the chordate, Ciona intestinalis,...
Delivery Method:
microinjection
Organism or Cell Type:
Ciona intestinalis (ascidian)
Citation Extract:
Oda-Ishii I, Kubo A, Kari W, Suzuki N, Rothbächer U, Satou Y. A Maternal System Initiating the Zygotic Developmental Program through Combinatorial Repression in the Ascidian Embryo. PLoS Genet. 2016;12(5):e1006045. doi:10.1371/journal.pgen.1006045.

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