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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Folate receptor 1 is necessary for neural plate cell apical constriction during Xenopus neural tube formation
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Citation:
Development. 2017;144:1518-30. doi: 10.1242/dev.137315 Epub:
Not Epub Abstract:
Folate supplementation prevents up to 70% of neural tube defects (NTDs), which result from a failure of neural tube closure... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Balashova OA, Visina O, Borodinsky LN. Folate receptor 1 is necessary for neural plate cell apical constriction during Xenopus neural tube formation. Development. 2017;144:1518-30. doi: 10.1242/dev.137315. |
Antisense Oligonucleotides Used to Target the DUX4 mRNA as Therapeutic Approaches in FaciosScapuloHumeral Muscular Dystrophy (FSHD)
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Citation:
Genes. 2017;8(3):93 doi:10.3390/genes8030093 Epub:
Not Epub Abstract:
FacioScapuloHumeral muscular Dystrophy (FSHD) is one of the most prevalent hereditary myopathies and is generally characterized... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mouse Citation Extract: Ansseau E, Vanderplanck C, Wauters A, Harper SQ, Coppée F, Belayew A. Antisense Oligonucleotides Used to Target the DUX4 mRNA as Therapeutic Approaches in FaciosScapuloHumeral Muscular Dystrophy (FSHD). Genes. 2017;8(3):93 doi:10.3390/genes8030093. |
The protein tyrosine phosphatase 1B inhibitor MSI-1436 stimulates regeneration of heart and multiple other tissues
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Citation:
npj Regen Med. 2017;2:4. doi:10.1038/s41536-017-0008-1 Epub:
Not Epub Abstract:
Regenerative medicine holds substantial promise for repairing or replacing tissues and organs damaged by disease, injury, and... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
zebrafish Citation Extract: Smith AM, Maguire-Nguyen KK, Rando TA, Zasloff MA, Strange KB, Yin VP. The protein tyrosine phosphatase 1B inhibitor MSI-1436 stimulates regeneration of heart and multiple other tissues. npj Regen Med. 2017;2:4. doi:10.1038/s41536-017-0008-1. |
The pro-inflammatory signalling regulator Stat4 promotes vasculogenesis of great vessels derived from endothelial precursors
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Citation:
Nat Comm. 2017;8:14640 doi:10.1038/ncomms14640 Epub:
Not Epub Abstract:
Vasculogenic defects of great vessels (GVs) are a major cause of congenital cardiovascular diseases. However, genetic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Meng Z-Z, Liu W, Xia Y, Yin H-M, Zhang C-Y, Su D, Yan L-F, Gu A-H, Zhou Y. The pro-inflammatory signalling regulator Stat4 promotes vasculogenesis of great vessels derived from endothelial precursors. Nat Comm. 2017;8:14640 doi:10.1038/ncomms14640. |
Sox10 contributes to the balance of fate choice in dorsal root ganglion progenitors
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Citation:
PLoS One. 2017 Mar 2;12(3):e0172947. doi: 10.1371/journal.pone.0172947 Epub:
Not Epub Abstract:
The development of functional peripheral ganglia requires a balance of specification of both neuronal and glial components. In... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Delfino-Machín M, Madelaine R, Busolin G, Nikaido M, Colanesi S, Camargo-Sosa K, Law EW, Toppo S, Blader P, Tiso N, Kelsh RN. Sox10 contributes to the balance of fate choice in dorsal root ganglion progenitors. PLoS One. 2017 Mar 2;12(3):e0172947. doi: 10.1371/journal.pone.0172947. |
Using Morpholinos to Control Gene Expression
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Citation:
Curr Protoc Nucleic Acid Chem. 2017 Mar 2;68:4.30.1-4.30.29. doi: 10.1002/cpnc.21 Epub:
Not Epub Abstract:
Morpholino oligonucleotides are stable, uncharged, water-soluble molecules used to block complementary sequences of RNA,... Citation Extract: Moulton JD. Using Morpholinos to Control Gene Expression. Curr Protoc Nucleic Acid Chem. 2017 Mar 2;68:4.30.1-4.30.29. doi: 10.1002/cpnc.21. |
tomm22 knockdown-mediated hepatocyte damages elicit both the formation of hybrid hepatocytes and biliary conversion to hepatocytes in zebrafish larvae
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Citation:
Gene Expr. 2017 Mar 1. doi: 10.3727/105221617X695195. [Epub ahead of print] Epub:
Yes Abstract:
The liver has a highly regenerative capacity. In the normal liver, hepatocytes proliferate to restore lost liver mass. However... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wu J, Choi TY, Shin D. tomm22 knockdown-mediated hepatocyte damages elicit both the formation of hybrid hepatocytes and biliary conversion to hepatocytes in zebrafish larvae. Gene Expr. 2017 Mar 1. doi: 10.3727/105221617X695195. [Epub ahead of print]. |
Myeloid and erythroid hematopoietic transcription factor expression decline after knockdown of lmna genes in zebrafish embryos
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Citation:
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2016 May 25;45(6):620-625. Chinese Epub:
Not Epub Abstract:
Objective: To investigate the effect of lmna gene down-regulation on early hematopoietic development of zebrafish. Methods:... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hou S, Wang Z, Wang J, He Z, Shu L. Myeloid and erythroid hematopoietic transcription factor expression decline after knockdown of lmna genes in zebrafish embryos. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2016 May 25;45(6):620-625. Chinese. |
R-spondin 1 is required for specification of hematopoietic stem cells through Wnt16 and Vegfa signaling pathways
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Citation:
Development. 2017 Feb 15;144(4):590-600. doi: 10.1242/dev.139956 Epub:
Not Epub Abstract:
Hematopoietic stem cells (HSCs) are the therapeutic component of bone marrow transplants, but finding immune-compatible donors... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Genthe JR, Clements WK. R-spondin 1 is required for specification of hematopoietic stem cells through Wnt16 and Vegfa signaling pathways. Development. 2017 Feb 15;144(4):590-600. doi: 10.1242/dev.139956. |
How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse
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Citation:
Hum Mol Genet. 2015 Aug 1;24(15):4225-37. doi: 10.1093/hmg/ddv155 Epub:
Not Epub Abstract:
Splice modulation therapy has shown great clinical promise in Duchenne muscular dystrophy, resulting in the production of... Delivery Method:
peptide-linked Organism or Cell Type:
mouse mdx Citation Extract: Godfrey C, Muses S, McClorey G, Wells KE, Coursindel T, Terry RL, Betts C, Hammond S, O'Donovan L, Hildyard J, El Andaloussi S, Gait MJ, Wood MJ, Wells DJ. How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse. Hum Mol Genet. 2015 Aug 1;24(15):4225-37. doi: 10.1093/hmg/ddv155. |