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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

The lncRNAs Implicated in Redox Regulation in Ybx1 Deficient Zebrafish Larvae

Authors:
Huang C, Zhu B, Leng D, Ge W, Zhang XD
Citation:
bioRxiv. 2019;[preprint] doi:/10.1101/679167
Epub:
Not Epub
Abstract:
Ybx1 has been demonstrated as a crucial gene in embryogenesis, reproduction as well as development in various vertebrates such...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Huang C, Zhu B, Leng D, Ge W, Zhang XD. The lncRNAs Implicated in Redox Regulation in Ybx1 Deficient Zebrafish Larvae. bioRxiv. 2019;[preprint] doi:/10.1101/679167.

Cell and tissue morphology determine actin-dependent nuclear migration mechanisms in neuroepithelia

Authors:
Yanakieva I, Erzberger A, Matejčić M, Modes CD, Norden C
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/536698
Epub:
Not Epub
Abstract:
Correct nuclear position is crucial for cellular function and tissue development. Depending on cell context however,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yanakieva I, Erzberger A, Matejčić M, Modes CD, Norden C. Cell and tissue morphology determine actin-dependent nuclear migration mechanisms in neuroepithelia. bioRxiv. 2019;[preprint] doi:10.1101/536698 .

Actomyosin regulation by Eph receptor signaling couples boundary cell formation to border sharpness

Authors:
Cayuso J, Xu Q, Addison M, Wilkinson DG
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/683631
Epub:
Not Epub
Abstract:
The segregation of cells with distinct regional identity underlies formation of a sharp border, which in some tissues serves to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cayuso J, Xu Q, Addison M, Wilkinson DG. Actomyosin regulation by Eph receptor signaling couples boundary cell formation to border sharpness. bioRxiv. 2019;[preprint] doi:10.1101/683631 .

ΔN-Tp63 mediates Wnt/β-catenin-induced inhibition of differentiation in basal stem cells of mucociliary epithelia

Authors:
Haas M, Vázquez JLG, Sun DI, Tran HT, Brislinger M, Tasca A, Shomroni O, Vleminckx K, Walentek P
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/682534
Epub:
Not Epub
Abstract:
Mucociliary epithelia provide a first line of defense against pathogens in the airways and the epidermis of vertebrate larvae....
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Haas M, Vázquez JLG, Sun DI, Tran HT, Brislinger M, Tasca A, Shomroni O, Vleminckx K, Walentek P. ΔN-Tp63 mediates Wnt/β-catenin-induced inhibition of differentiation in basal stem cells of mucociliary epithelia. bioRxiv. 2019;[preprint] doi:10.1101/682534.

Dephosphorylation of HDAC4 by PP2A-Bδ unravels a new role for the HDAC4/MEF2 axis in myoblast fusion

Authors:
Veloso A, Martin M, Bruyr J, O’Grady T, Deroanne C, Mottet D, Twizere J-C, Cherrier T, Dequiedt F
Citation:
Cell Death & Dis. 2019;10(7):512. doi:10.1038/s41419-019-1743-6
Epub:
Not Epub
Abstract:
Muscle formation is controlled by a number of key myogenic transcriptional regulators that govern stage-specific gene...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Veloso A, Martin M, Bruyr J, O’Grady T, Deroanne C, Mottet D, Twizere J-C, Cherrier T, Dequiedt F. Dephosphorylation of HDAC4 by PP2A-Bδ unravels a new role for the HDAC4/MEF2 axis in myoblast fusion. Cell Death & Dis. 2019;10(7):512. doi:10.1038/s41419-019-1743-6.

NIPBL: a new player in myeloid cell differentiation

Authors:
Mazzola M, Deflorian G, Pezzotta A, Ferrari L, Fazio G, Bresciani E, Saitta C, Ferrari L, Fumagalli M, Parma M, Marasca F, Bodega B, Riva P, Cotelli F, Biondi A, Marozzi A, Cazzaniga G, Pistocchi A
Citation:
Haematologica. 2019 Jul;104(7):1332-1341. doi: 10.3324/haematol.2018.200899. Epub 2019 Jan 10
Epub:
Not Epub
Abstract:
The nucleophosmin 1 gene (NPM1) is the most frequently mutated gene in acute myeloid leukemia. Notably, NPM1 mutations are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mazzola M, Deflorian G, Pezzotta A, Ferrari L, Fazio G, Bresciani E, Saitta C, Ferrari L, Fumagalli M, Parma M, Marasca F, Bodega B, Riva P, Cotelli F, Biondi A, Marozzi A, Cazzaniga G, Pistocchi A. NIPBL: a new player in myeloid cell differentiation. Haematologica. 2019 Jul;104(7):1332-1341. doi: 10.3324/haematol.2018.200899. Epub 2019 Jan 10.

DYRK1A-related intellectual disability: a syndrome associated with congenital anomalies of the kidney and urinary tract

Authors:
Blackburn ATM, Bekheirnia N, Uma VC, Corkins ME, Xu Y, Rosenfeld JA, Bainbridge MN, Yang Y, Liu P, Madan-Khetarpal S, Delgado MR, Hudgins L, Krantz I, Rodriguez-Buritica D, Wheeler PG, Gazali LA, Mohamed Saeed Mohamed Al Shamsi A, Gomez-Ospina N, Chao HT, Mirzaa GM, Scheuerle AE, Kukolich MK, Scaglia F, Eng C, Willsey HR, Braun MC, Lamb DJ, Miller RK, Bekheirnia MR
Citation:
Genet Med. 2019 Jul 2. doi: 10.1038/s41436-019-0576-0. [Epub ahead of print]
Epub:
Yes
Abstract:
PURPOSE: Haploinsufficiency of DYRK1A causes a recognizable clinical syndrome. The goal of this paper is to investigate...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Blackburn ATM, Bekheirnia N, Uma VC, Corkins ME, Xu Y, Rosenfeld JA, Bainbridge MN, Yang Y, Liu P, Madan-Khetarpal S, Delgado MR, Hudgins L, Krantz I, Rodriguez-Buritica D, Wheeler PG, Gazali LA, Mohamed Saeed Mohamed Al Shamsi A, Gomez-Ospina N, Chao HT, Mirzaa GM, Scheuerle AE, Kukolich MK, Scaglia F, Eng C, Willsey HR, Braun MC, Lamb DJ, Miller RK, Bekheirnia MR. DYRK1A-related intellectual disability: a syndrome associated with congenital anomalies of the kidney and urinary tract. Genet Med. 2019 Jul 2. doi: 10.1038/s41436-019-0576-0. [Epub ahead of print].

Developmentally regulated GTP-binding protein 1 modulates ciliogenesis via an interaction with Dishevelled

Authors:
Lee M, Hwang YS, Yoon J, Sun J, Harned A, Nagashima K, Daar IO
Citation:
J Cell Biol. 2019 Jul 3. pii: jcb.201811147. doi: 10.1083/jcb.201811147. [Epub ahead of print]
Epub:
Yes
Abstract:
Cilia are critical for proper embryonic development and maintaining homeostasis. Although extensively studied, there are still...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Lee M, Hwang YS, Yoon J, Sun J, Harned A, Nagashima K, Daar IO. Developmentally regulated GTP-binding protein 1 modulates ciliogenesis via an interaction with Dishevelled. J Cell Biol. 2019 Jul 3. pii: jcb.201811147. doi: 10.1083/jcb.201811147. [Epub ahead of print].

Long-term treatment with eteplirsen in nonambulatory patients with Duchenne muscular dystrophy

Authors:
Alfano LN, Charleston JS, Connolly AM, Cripe L, Donoghue C, Dracker R, Dworzak J, Eliopoulos H, Frank DE, Lewis S, Lucas K, Lynch J, Milici AJ, Flynt A, Naughton E, Rodino-Klapac LR, Sahenk Z, Schnell FJ, Young GD, Mendell JR, Lowes LP
Citation:
Medicine (Baltimore). 2019 Jun;98(26):e15858. doi: 10.1097/MD.0000000000015858
Epub:
Not Epub
Abstract:
This analysis aims to describe the outcomes of two nonambulatory patients with Duchenne muscular dystrophy (DMD) who...
Delivery Method:
i.v. infusion
Organism or Cell Type:
human
Citation Extract:
Alfano LN, Charleston JS, Connolly AM, Cripe L, Donoghue C, Dracker R, Dworzak J, Eliopoulos H, Frank DE, Lewis S, Lucas K, Lynch J, Milici AJ, Flynt A, Naughton E, Rodino-Klapac LR, Sahenk Z, Schnell FJ, Young GD, Mendell JR, Lowes LP. Long-term treatment with eteplirsen in nonambulatory patients with Duchenne muscular dystrophy. Medicine (Baltimore). 2019 Jun;98(26):e15858. doi: 10.1097/MD.0000000000015858.

Functional muscle recovery following dystrophin and myostatin exon splice modulation in aged mdx mice

Authors:
Lu-Nguyen N, Ferry A, Schnell FJ, Hanson GJ, Popplewell L, Dickson G, Malerba A
Citation:
Hum Mol Genet. 2019 Jun 10. pii: ddz125. doi: 10.1093/hmg/ddz125. [Epub ahead of print]
Epub:
Yes
Abstract:
Duchenne muscular dystrophy (DMD) is a rare genetic disease affecting 1 in 3500-5000 newborn boys. It is due to mutations in...
Organism or Cell Type:
mice mdx
Citation Extract:
Lu-Nguyen N, Ferry A, Schnell FJ, Hanson GJ, Popplewell L, Dickson G, Malerba A. Functional muscle recovery following dystrophin and myostatin exon splice modulation in aged mdx mice. Hum Mol Genet. 2019 Jun 10. pii: ddz125. doi: 10.1093/hmg/ddz125. [Epub ahead of print].

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