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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
12-Lipoxygenase Governs the Innate Immune Pathogenesis of Islet Inflammation and Autoimmune Diabetes
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.01.02.424855 Epub:
Not Epub Abstract:
Macrophages and related myeloid cells are innate immune cells that participate in the early islet inflammation of type 1... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kulkarni A, Pineros AR, Ibrahim S, Hernandez-Perez M, Orr KS, Glenn L, Walsh M, Nadler JL, Morris MA, Tersey SA, Mirmira RG, Anderson RM. 12-Lipoxygenase Governs the Innate Immune Pathogenesis of Islet Inflammation and Autoimmune Diabetes. bioRxiv. 2021;[preprint] doi:10.1101/2021.01.02.424855 . |
Time-dependent pleiotropic phenotypes are caused by progressive DNA polymerase α deficiency in zebrafish
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.12.31.425001 Epub:
Not Epub Abstract:
The mechanisms underlying variation in cell- and tissue-specific phenotypes caused by mutations are poorly understood. For... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lin AY-S, Thomas GK, Ang K, van Rossum DB, Canfield VA, Cheng IKC. Time-dependent pleiotropic phenotypes are caused by progressive DNA polymerase α deficiency in zebrafish. bioRxiv. 2020;[preprint] doi:10.1101/2020.12.31.425001. |
Loss of PIGK function causes severe infantile encephalopathy and extensive neuronal apoptosis
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Citation:
Hum Genet. 2021 Jan 4. doi: 10.1007/s00439-020-02243-2. Online ahead of print Epub:
Yes Abstract:
PIGK gene, encoding a key component of glycosylphosphatidylinositol (GPI) transamidase, was recently reported to be associated... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen X, Yin W, Chen S, Zhang W, Li H, Kuang H, Zhou M, Teng Y, Zhang J, Shen G, Liang D, Li Z, Hu B, Wu L. Loss of PIGK function causes severe infantile encephalopathy and extensive neuronal apoptosis. Hum Genet. 2021 Jan 4. doi: 10.1007/s00439-020-02243-2. Online ahead of print. |
HSP60 regulates monosodium urate crystal-induced inflammation by activating the TLR4-NF- κ B-MyD88 signaling pathway and disrupting mitochondrial function
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Citation:
Oxid Med Cell Longev. 2020;[Epub] doi:10.1155/2020/8706898 Epub:
Yes Abstract:
Acute gout is an inflammatory response induced by monosodium urate (MSU) crystals. HSP60 is a highly conserved stress protein... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Gao W, Huang Q, Qin T, Mu H, Long F, Ren L, Tang H, Liu J, Zeng M. HSP60 regulates monosodium urate crystal-induced inflammation by activating the TLR4-NF- κ B-MyD88 signaling pathway and disrupting mitochondrial function. Oxid Med Cell Longev. 2020;[Epub] doi:10.1155/2020/8706898. |
A globin-family protein, cytoglobin 1, is involved in the development of neural crest-derived tissues and organs in zebrafish
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Citation:
Dev Biol. 2020 Dec 22:S0012-1606(20)30325-0. doi: 10.1016/j.ydbio.2020.12.016. Online ahead of print Epub:
Yes Abstract:
The zebrafish is an excellent model animal that is amenable to forward genetics approaches. To uncover unknown developmental... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Takahashi K, Ito Y, Yoshimura M, Nikaido M, Yuikawa T, Kawamura A, Tsuda S, Kage D, Yamasu K. A globin-family protein, cytoglobin 1, is involved in the development of neural crest-derived tissues and organs in zebrafish. Dev Biol. 2020 Dec 22:S0012-1606(20)30325-0. doi: 10.1016/j.ydbio.2020.12.016. Online ahead of print. |
CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1
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Citation:
Signal Transduct Target Ther. 2020 Dec 26;5(1):298. doi: 10.1038/s41392-020-00375-5 Epub:
Not Epub Abstract:
Sorafenib is the first-line chemotherapeutic therapy for advanced hepatocellular carcinoma (HCC). However, sorafenib resistance... Organism or Cell Type:
cell culture: HepG2-SR Citation Extract: Xu J, Ji L, Liang Y, Wan Z, Zheng W, Song X, Gorshkov K, Sun Q, Lin H, Zheng X, Chen J, Jin RA, Liang X, Cai X. CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1. Signal Transduct Target Ther. 2020 Dec 26;5(1):298. doi: 10.1038/s41392-020-00375-5. |
ace2 expression is higher in intestines and liver while being tightly regulated in development and disease in zebrafish
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.12.24.424209 Epub:
Not Epub Abstract:
Human Angiotensin I Converting Enzyme 2 (ACE2) that acts as a receptor for SARS-CoV-2 entry is highly expressed in human type... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ayse Gokce Keskus, Melike Tombaz, Burcin I. Arici, Fatma B. Dincaslan, Afshan Nabi, Huma Shehwana, Ozlen Konu. ace2 expression is higher in intestines and liver while being tightly regulated in development and disease in zebrafish. bioRxiv. 2020;[preprint] doi:10.1101/2020.12.24.424209. |
Mutation in epsilon-Sarcoglycan Induces a Myoclonus-Dystonia Syndrome-Like Movement Disorder in Mice
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Citation:
Neurosci Bull. 2020 Dec 23. doi: 10.1007/s12264-020-00612-5. Online ahead of print Epub:
Not Epub Abstract:
Myoclonus dystonia syndrome (MDS) is an inherited movement disorder, and most MDS-related mutations have so far been found in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li J, Liu Y, Li Q, Huang X, Zhou D, Xu H, Zhao F, Mi X, Wang R, Jia F, Xu F, Yang J, Liu D, Deng X, Zhang Y. Mutation in epsilon-Sarcoglycan Induces a Myoclonus-Dystonia Syndrome-Like Movement Disorder in Mice. Neurosci Bull. 2020 Dec 23. doi: 10.1007/s12264-020-00612-5. Online ahead of print. |
Discovery and mechanistic characterization of a novel AhR receptor ligand that induces apoptosis in cancer cells
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Citation:
Research Square. 2020;[preprint] doi:10.21203/rs.3.rs-131951/v1 Epub:
Not Epub Abstract:
Background: The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor and a member of the bHLH/PAS (basic... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: Hepa 1 Citation Extract: O'Donnell E, Jang HS, Liefwalker D, Kerkvliet N, Kolluri SK. Discovery and mechanistic characterization of a novel AhR receptor ligand that induces apoptosis in cancer cells. Research Square. 2020;[preprint] doi:10.21203/rs.3.rs-131951/v1. |
Transcriptome Profile of the Sinoatrial Ring Reveals Conserved and Novel Genetic Programs of the Zebrafish Pacemaker
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Citation:
Research Square. 2020;[preprint] doi:10.21203/rs.3.rs-130687/v1 Epub:
Not Epub Abstract:
Background: Sinoatrial Node (SAN) is part of the cardiac conduction system, which controls the rhythmic contraction of the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Minhas R, Loeffler-Wirth H, Siddiqui Y, Obrebski T, Vhashist S, Nahia KA, Paterek A, Brzozowska A, Bugajski L, Piwocka K, Korzh V, Binder H, Winata CL. Transcriptome Profile of the Sinoatrial Ring Reveals Conserved and Novel Genetic Programs of the Zebrafish Pacemaker. Research Square. 2020;[preprint] doi:10.21203/rs.3.rs-130687/v1. |