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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Transcriptional and post-transcriptional regulation of histone variant H2A.Z during sea urchin development

Authors:
Hajdu M, Calle J, Puno A, Haruna A, Arenas-Mena C
Citation:
Dev Growth Differ. 2016 Nov 29. doi: 10.1111/dgd.12329. [Epub ahead of print]
Epub:
Yes
Abstract:
Histone variant H2A.Z promotes chromatin accessibility at transcriptional regulatory elements and is developmentally regulated...
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Hajdu M, Calle J, Puno A, Haruna A, Arenas-Mena C. Transcriptional and post-transcriptional regulation of histone variant H2A.Z during sea urchin development. Dev Growth Differ. 2016 Nov 29. doi: 10.1111/dgd.12329. [Epub ahead of print].

SVEP1 plays a crucial role in epidermal differentiation

Authors:
Samuelov L, Li Q, Bochner R, Najor N, Albrecht L, Malchin N, Goldsmith T, Grafi-Cohen M, Vodo D, Fainberg G, Meilik B, Goldberg I, Warshauer E, Rogers T, Edie S, Ishida-Yamamoto A, Burzenski L, Erez N, Murray SA, Irvine AD, Shultz L, Green K, Uitto J, Sprecher E, Sarig O
Citation:
Exp Dermatol. 2016 Nov 28. doi: 10.1111/exd.13256. [Epub ahead of print]
Epub:
Yes
Abstract:
SVEP1 is a recently identified multi-domain cell adhesion protein, homologous to the mouse polydom protein, which has been...
Organism or Cell Type:
zebrafish
Citation Extract:
Samuelov L, Li Q, Bochner R, Najor N, Albrecht L, Malchin N, Goldsmith T, Grafi-Cohen M, Vodo D, Fainberg G, Meilik B, Goldberg I, Warshauer E, Rogers T, Edie S, Ishida-Yamamoto A, Burzenski L, Erez N, Murray SA, Irvine AD, Shultz L, Green K, Uitto J, Sprecher E, Sarig O. SVEP1 plays a crucial role in epidermal differentiation. Exp Dermatol. 2016 Nov 28. doi: 10.1111/exd.13256. [Epub ahead of print].

Down-regulation of coasy, the gene associated with NBIA-VI, reduces Bmp signaling, perturbs dorso-ventral patterning and alters neuronal development in zebrafish

Authors:
Khatri D, Zizioli D, Tiso N, Facchinello N, Vezzoli S, Gianoncelli A, Memo M, Monti E, Borsani G, Finazzi D
Citation:
Sci Rep. 2016 Nov 28;6:37660. doi: 10.1038/srep37660
Epub:
Not Epub
Abstract:
Mutations in Pantothenate kinase 2 and Coenzyme A (CoA) synthase (COASY), genes involved in CoA biosynthesis, are associated...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Khatri D, Zizioli D, Tiso N, Facchinello N, Vezzoli S, Gianoncelli A, Memo M, Monti E, Borsani G, Finazzi D. Down-regulation of coasy, the gene associated with NBIA-VI, reduces Bmp signaling, perturbs dorso-ventral patterning and alters neuronal development in zebrafish. Sci Rep. 2016 Nov 28;6:37660. doi: 10.1038/srep37660.

The expression of chemorepulsive guidance receptors and the regenerative abilities of spinal-projecting neurons after spinal cord injury

Authors:
Chen J, Laramore C, Shifman MI
Citation:
Neuroscience. 2016 Nov 24. pii: S0306-4522(16)30641-8. doi: 10.1016/j.neuroscience.2016.11.020. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Spinal cord injury (SCI) in mammals leads to permanent loss of function because axons do not regenerate in the central nervous...
Organism or Cell Type:
lamprey
Citation Extract:
Chen J, Laramore C, Shifman MI. The expression of chemorepulsive guidance receptors and the regenerative abilities of spinal-projecting neurons after spinal cord injury. Neuroscience. 2016 Nov 24. pii: S0306-4522(16)30641-8. doi: 10.1016/j.neuroscience.2016.11.020. [Epub ahead of print].

Functional validation of ABHD12 mutations in the neurodegenerative disease PHARC

Authors:
Tingaud-Sequeira A, Raldúa D, Lavie J, Mathieu G, Bordier M, Knoll-Gellida A, Rambeau P, Coupry I, André M, Malm E, Möller C, Andreasson S, Rendtorff ND, Tranebjærg L, Koenig M, Lacombe D, Goizet C, Babin PJ
Citation:
Neurobiol Dis. 2016 Nov 23. pii: S0969-9961(16)30267-4. doi: 10.1016/j.nbd.2016.11.008. [Epub ahead of print]
Epub:
Yes
Abstract:
BHD12 mutations have been linked to neurodegenerative PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tingaud-Sequeira A, Raldúa D, Lavie J, Mathieu G, Bordier M, Knoll-Gellida A, Rambeau P, Coupry I, André M, Malm E, Möller C, Andreasson S, Rendtorff ND, Tranebjærg L, Koenig M, Lacombe D, Goizet C, Babin PJ. Functional validation of ABHD12 mutations in the neurodegenerative disease PHARC. Neurobiol Dis. 2016 Nov 23. pii: S0969-9961(16)30267-4. doi: 10.1016/j.nbd.2016.11.008. [Epub ahead of print].

The role of RhoA in retrograde neuronal death and axon regeneration after spinal cord injury

Authors:
Hu J, Zhang G, Rodemer W, Jin LQ, Shifman M, Selzer ME
Citation:
Neurobiol Dis. 2016 Nov 22. pii: S0969-9961(16)30264-9. doi: 10.1016/j.nbd.2016.11.006. [Epub ahead of print]
Epub:
Yes
Abstract:
Paralysis following spinal cord injury (SCI) is due to interruption of axons and their failure to regenerate. It has been...
Delivery Method:
injection
Organism or Cell Type:
sea lamprey
Citation Extract:
Hu J, Zhang G, Rodemer W, Jin LQ, Shifman M, Selzer ME. The role of RhoA in retrograde neuronal death and axon regeneration after spinal cord injury. Neurobiol Dis. 2016 Nov 22. pii: S0969-9961(16)30264-9. doi: 10.1016/j.nbd.2016.11.006. [Epub ahead of print].

Synthesis of a Morpholino Nucleic Acid (MNA)-Uridine Phosphoramidite, and Exon Skipping Using MNA/2'-O-Methyl Mixmer Antisense Oligonucleotide

Authors:
Chen S, Le BT, Rahimizadeh K, Shaikh K, Mohal N, Veedu RN
Citation:
Molecules. 2016 Nov 22;21(11). pii: E1582
Epub:
Not Epub
Abstract:
In this study, we synthesised a morpholino nucleoside-uridine (MNA-U) phosphoramidite and evaluated the potential of a MNA-...
Delivery Method:
Lipofectin
Organism or Cell Type:
cultured cells: Immortalised mdx myoblasts (H2K cells)
Citation Extract:
Chen S, Le BT, Rahimizadeh K, Shaikh K, Mohal N, Veedu RN. Synthesis of a Morpholino Nucleic Acid (MNA)-Uridine Phosphoramidite, and Exon Skipping Using MNA/2'-O-Methyl Mixmer Antisense Oligonucleotide. Molecules. 2016 Nov 22;21(11). pii: E1582.

MicroRNAs regulate gene plasticity during cold shock in zebrafish larvae

Authors:
Hung IC, Hsiao YC, Sun HS, Chen TM, Lee SJ
Citation:
BMC Genomics. 2016 Nov 15;17(1):922
Epub:
Not Epub
Abstract:
BACKGROUND: MicroRNAs (miRNAs) are critical regulators responding to acute environmental stresses in both plants and animals....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hung IC, Hsiao YC, Sun HS, Chen TM, Lee SJ. MicroRNAs regulate gene plasticity during cold shock in zebrafish larvae. BMC Genomics. 2016 Nov 15;17(1):922.

The sensitivity of the DNA damage checkpoint prevents oocyte maturation in endometriosis

Authors:
Hamdan M, Jones KT, Cheong Y, Lane SI
Citation:
Sci Rep. 2016 Nov 14;6:36994. doi: 10.1038/srep36994
Epub:
Not Epub
Abstract:
Mouse oocytes respond to DNA damage by arresting in meiosis I through activity of the Spindle Assembly Checkpoint (SAC) and DNA...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Hamdan M, Jones KT, Cheong Y, Lane SI. The sensitivity of the DNA damage checkpoint prevents oocyte maturation in endometriosis. Sci Rep. 2016 Nov 14;6:36994. doi: 10.1038/srep36994.

Synthesis of Phosphorodiamidate Morpholino Oligonucleotides and Their Chimeras Using Phosphoramidite Chemistry

Authors:
Paul S, Caruthers MH
Citation:
J Am Chem Soc. 2016;[Epub ahead of print] doi:10.1021/jacs.6b08854
Epub:
Yes
Abstract:
Phosphorodiamidate morpholinos (PMOs) and PMO-DNA chimeras have been prepared on DNA synthesizers using phosphoramidite...
Citation Extract:
Paul S, Caruthers MH. Synthesis of Phosphorodiamidate Morpholino Oligonucleotides and Their Chimeras Using Phosphoramidite Chemistry. J Am Chem Soc. 2016;[Epub ahead of print] doi:10.1021/jacs.6b08854.

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