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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

BACH family members regulate angiogenesis and lymphangiogenesis by modulating VEGFC expression

Authors:
Cohen B, Tempelhof H, Raz T, Oren R, Nicenboim J, Bochner F, Even R, Jelinski A, Eilam R, Ben-Dor S, Addadi Y, Golani O, Lazar S, Yaniv K, Neeman M
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/2019.12.13.876268
Epub:
Not Epub
Abstract:
Angiogenesis and lymphangiogenesis are key processes during embryogenesis as well as under physiological and pathological...
Link:
https://www.biorxiv.org/content/10.1101/2019.12.13.876268v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cohen B, Tempelhof H, Raz T, Oren R, Nicenboim J, Bochner F, Even R, Jelinski A, Eilam R, Ben-Dor S, Addadi Y, Golani O, Lazar S, Yaniv K, Neeman M. BACH family members regulate angiogenesis and lymphangiogenesis by modulating VEGFC expression. bioRxiv. 2019;[preprint] doi:10.1101/2019.12.13.876268.

SCGN deficiency results in colitis susceptibility

Authors:
Sifuentes-Dominguez LF, Li H, Llano E, Liu Z, Singla A, Patel AS, Kathania M, Khoury A, Norris N, Rios JJ, Starokadomskyy P, Park JY, Gopal P, Liu Q, Tan S, Chan L, Ross T, Harrison S, Venuprasad K, Baker LA, Jia D, Burstein E
Citation:
Elife. 2019 Oct 30;8. pii: e49910. doi:10.7554/eLife.49910
Epub:
Not Epub
Abstract:
Inflammatory bowel disease (IBD) affects 1.5-3.0 million people in the United States. IBD is genetically determined and many...
Link:
https://elifesciences.org/articles/49910
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sifuentes-Dominguez LF, Li H, Llano E, Liu Z, Singla A, Patel AS, Kathania M, Khoury A, Norris N, Rios JJ, Starokadomskyy P, Park JY, Gopal P, Liu Q, Tan S, Chan L, Ross T, Harrison S, Venuprasad K, Baker LA, Jia D, Burstein E. SCGN deficiency results in colitis susceptibility. Elife. 2019 Oct 30;8. pii: e49910. doi:10.7554/eLife.49910.

Systems genetics analysis identify calcium signalling defects as novel cause of congenital heart disease

Authors:
Izarzugaza JMG, Ellesøe SG, Doganli C, Ehlers NS, Dalgaard MD, Audain E, Dombrowsky G, Sifrim A, Wilsdon A, Thienpont B, Breckpot J, Gewillig M, Competence Network for Congenital Heart Defects, Germany, Brook JD, Hitz M-P, Larsen LA, Brunak S
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/2019.12.11.872424
Epub:
Not Epub
Abstract:
Background: Congenital heart disease (CHD) occurs in almost 1% of newborn children and is considered a multifactorial disorder...
Link:
https://www.biorxiv.org/content/10.1101/2019.12.11.872424v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Izarzugaza JMG, Ellesøe SG, Doganli C, Ehlers NS, Dalgaard MD, Audain E, Dombrowsky G, Sifrim A, Wilsdon A, Thienpont B, Breckpot J, Gewillig M, Competence Network for Congenital Heart Defects, Germany, Brook JD, Hitz M-P, Larsen LA, Brunak S. Systems genetics analysis identify calcium signalling defects as novel cause of congenital heart disease. bioRxiv. 2019;[preprint] doi:10.1101/2019.12.11.872424.

Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence

Authors:
Torraca V, Kaforou M, Watson J, Duggan GM, Guerrero-Gutierrez H, Krokowski S, Hollinshead M, Thomas B. Clarke TB, Mostowy RJ, Tomlinson GS, Sancho-Shimizu V, Clements A, Mostowy S
Citation:
PLoS Pathog. 2019;15(12):e1008006. doi:10.1371/journal.ppat.1008006
Epub:
Not Epub
Abstract:
Shigella flexneri is historically regarded as the primary agent of bacillary dysentery, yet the closely-related Shigella sonnei...
Link:
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1008006
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Torraca V, Kaforou M, Watson J, Duggan GM, Guerrero-Gutierrez H, Krokowski S, Hollinshead M, Thomas B. Clarke TB, Mostowy RJ, Tomlinson GS, Sancho-Shimizu V, Clements A, Mostowy S. Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence. PLoS Pathog. 2019;15(12):e1008006. doi:10.1371/journal.ppat.1008006.

Developmentally regulated Tcf7l2 splice variants mediate transcriptional repressor functions during eye formation

Authors:
Young RM, Ewan KB, Ferrer VP, Allende ML, Godovac-Zimmermann J, Dale TC, Wilson SW
Citation:
eLife. 2019;8:e51447. doi:10.7554/eLife.51447
Epub:
Not Epub
Abstract:
Tcf7l2 mediates Wnt/β-Catenin signalling during development and is implicated in cancer and type-2 diabetes. The mechanisms by...
Link:
https://elifesciences.org/articles/51447
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Young RM, Ewan KB, Ferrer VP, Allende ML, Godovac-Zimmermann J, Dale TC, Wilson SW. Developmentally regulated Tcf7l2 splice variants mediate transcriptional repressor functions during eye formation. eLife. 2019;8:e51447. doi:10.7554/eLife.51447.

Neural crest cells bulldoze through the microenvironment using Aquaporin-1 to stabilize filopodia

Authors:
McLennan R, McKinney MC, Teddy JM, Morrison JA, Kasemeier-Kulesa JC, Ridenour DA, Manthe CA, Giniunaite R, Robinson M, Baker RE, Maini PK, Kulesa PM
Citation:
Development. 2019 Dec 11. pii: dev.185231. doi: 10.1242/dev.185231. [Epub ahead of print]
Epub:
Yes
Abstract:
Neural crest migration requires cells to move through an environment filled with dense extracellular matrix and mesoderm to...
Link:
https://dev.biologists.org/content/early/2019/12/10/dev.185231
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
McLennan R, McKinney MC, Teddy JM, Morrison JA, Kasemeier-Kulesa JC, Ridenour DA, Manthe CA, Giniunaite R, Robinson M, Baker RE, Maini PK, Kulesa PM. Neural crest cells bulldoze through the microenvironment using Aquaporin-1 to stabilize filopodia. Development. 2019 Dec 11. pii: dev.185231. doi: 10.1242/dev.185231. [Epub ahead of print].

AHR-mediated ROS production contributes to the cardiac developmental toxicity of PM2.5 in zebrafish embryos

Authors:
Ren F, Ji C, Huang Y, Aniagu S, Jiang Y, Chen T
Citation:
Sci Total Environ. 2019 Nov 21:135097. doi: 10.1016/j.scitotenv.2019.135097. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Recent studies have shown an association between maternal exposure to ambient fine particle matter (PM2.5) and congenital heart...
Link:
https://www.sciencedirect.com/science/article/pii/S0048969719350892
Organism or Cell Type:
zebrafish
Citation Extract:
Ren F, Ji C, Huang Y, Aniagu S, Jiang Y, Chen T. AHR-mediated ROS production contributes to the cardiac developmental toxicity of PM2.5 in zebrafish embryos. Sci Total Environ. 2019 Nov 21:135097. doi: 10.1016/j.scitotenv.2019.135097. [Epub ahead of print].

Gene duplication and functional divergence of the zebrafish otospiralin genes

Authors:
Aissette B, Sepand R, Amal B, Masanari T, Vanessa G, Amal S, Tanja B, Olfa J, Uwe S, Saber M
Citation:
Dev Genes Evol. 2019 Dec 14. doi: 10.1007/s00427-019-00642-8. [Epub ahead of print]
Epub:
Yes
Abstract:
Otospiralin (OTOSP) is a small protein of unknown function, expressed in fibrocytes of the inner ear and required for normal...
Link:
https://link.springer.com/article/10.1007%2Fs00427-019-00642-8
Organism or Cell Type:
zebrafish
Citation Extract:
Aissette B, Sepand R, Amal B, Masanari T, Vanessa G, Amal S, Tanja B, Olfa J, Uwe S, Saber M. Gene duplication and functional divergence of the zebrafish otospiralin genes. Dev Genes Evol. 2019 Dec 14. doi: 10.1007/s00427-019-00642-8. [Epub ahead of print].

Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9

Authors:
Sun Y, Zhang B, Luo L, Shi DL, Wang H, Cui Z, Huang H, Cao Y, Shu X, Zhang W, Zhou J, Li Y, Du J, Zhao Q, Chen J, Zhong H, Zhong TP, Li L, Xiong JW, Peng J, Xiao W, Zhang J, Yao J, Yin Z, Mo X, Peng G, Zhu J, Chen Y, Zhou Y, Liu D, Pan W, Zhang Y, Ruan H, Liu F, Zhu Z, Meng A; ZAKOC Consortium
Citation:
Genome Res. 2019 Dec 12. doi: 10.1101/gr.248559.119. [Epub ahead of print]
Epub:
Yes
Abstract:
Genome editing by the well-established CRISPR/Cas9 technology has greatly facilitated our understanding of many biological...
Link:
https://genome.cshlp.org/content/early/2019/12/12/gr.248559.119.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun Y, Zhang B, Luo L, Shi DL, Wang H, Cui Z, Huang H, Cao Y, Shu X, Zhang W, Zhou J, Li Y, Du J, Zhao Q, Chen J, Zhong H, Zhong TP, Li L, Xiong JW, Peng J, Xiao W, Zhang J, Yao J, Yin Z, Mo X, Peng G, Zhu J, Chen Y, Zhou Y, Liu D, Pan W, Zhang Y, Ruan H, Liu F, Zhu Z, Meng A; ZAKOC Consortium. Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9. Genome Res. 2019 Dec 12. doi: 10.1101/gr.248559.119. [Epub ahead of print].

Ectoderm to mesoderm transition by downregulation of actomyosin contractility

Authors:
Kashkooli L, Rozema D, Espejo-Ramirez L, Lasko P, Fagotto F
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/870444
Epub:
Not Epub
Abstract:
Collective migration of cohesive tissues is a fundamental process in morphogenesis, and is particularly well illustrated during...
Link:
https://www.biorxiv.org/content/10.1101/870444v2
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Kashkooli L, Rozema D, Espejo-Ramirez L, Lasko P, Fagotto F. Ectoderm to mesoderm transition by downregulation of actomyosin contractility. bioRxiv. 2019;[preprint] doi:10.1101/870444.

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