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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Igf2bp1 is required for hepatic outgrowth during early liver development in zebrafish

Authors:
Wu J, Lu C, Ge S, Mei J, Li X, Guo W
Citation:
Gene. 2020 Mar 30:144632. doi: 10.1016/j.gene.2020.144632. [Epub ahead of print]
Epub:
Yes
Abstract:
IGF2BPs, a subclass of RNA-binding proteins, regulate cellular differentiation, proliferation and migration during multiple...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0378111920303012
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu J, Lu C, Ge S, Mei J, Li X, Guo W. Igf2bp1 is required for hepatic outgrowth during early liver development in zebrafish. Gene. 2020 Mar 30:144632. doi: 10.1016/j.gene.2020.144632. [Epub ahead of print].

Systematic Chromatin Architecture Analysis in Xenopus tropicalis Reveals Conserved Three-Dimensional Folding Principles of Vertebrate Genomes

Authors:
Niu L, Shen W, Shi Z, He N, Wan J, Sun J, Zhang Y, Huang Y, Wenjing Wang W, Fang C, Li J, Zheng P, Cheung E, Chen Y, Li L, Hou C
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.04.02.021378
Epub:
Not Epub
Abstract:
Metazoan genomes are folded into 3D structures in interphase nuclei. However, the molecular mechanism remains unknown. Here, we...
Link:
https://www.biorxiv.org/content/10.1101/2020.04.02.021378v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Niu L, Shen W, Shi Z, He N, Wan J, Sun J, Zhang Y, Huang Y, Wenjing Wang W, Fang C, Li J, Zheng P, Cheung E, Chen Y, Li L, Hou C. Systematic Chromatin Architecture Analysis in Xenopus tropicalis Reveals Conserved Three-Dimensional Folding Principles of Vertebrate Genomes. bioRxiv. 2020;[preprint] doi:10.1101/2020.04.02.021378.

NvPOU4/Brain3 functions as a terminal selector gene in the nervous system of the cnidarian Nematostella vectensis

Authors:
Tournière O, Dolan D, Richards GS, Sunagar K, Columbus-Shenkar YY, Moran Y, Rentzsch F
Citation:
Cell Rep. 2020;40(13):4473-89. doi:10.1016/j.celrep.2020.03.031
Epub:
Not Epub
Abstract:
Terminal selectors are transcription factors that control the morphological, physiological, and molecular features that...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(20)30345-4
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Tournière O, Dolan D, Richards GS, Sunagar K, Columbus-Shenkar YY, Moran Y, Rentzsch F. NvPOU4/Brain3 functions as a terminal selector gene in the nervous system of the cnidarian Nematostella vectensis. Cell Rep. 2020;40(13):4473-89. doi:10.1016/j.celrep.2020.03.031.

Golodirsen

Authors:
The LiverTox team
Citation:
LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. 2020 Feb 27
Epub:
Not Epub
Abstract:
Golodirsen is synthetic antisense oligonucleotide designed to cause skipping of abnormal exons in the synthesis of the...
Link:
https://www.ncbi.nlm.nih.gov/books/NBK555332/
Citation Extract:
The LiverTox team. Golodirsen. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. 2020 Feb 27.

Eteplirsen

Authors:
The LiverTox team
Citation:
LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. 2020 Feb 27
Epub:
Not Epub
Abstract:
Eteplirsen is synthetic antisense oligonucleotide designed to cause skipping of abnormal exons during synthesis of the...
Link:
https://www.ncbi.nlm.nih.gov/books/NBK555333/
Citation Extract:
The LiverTox team. Eteplirsen. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. 2020 Feb 27.

EphA7 is required for otic epithelial homeostasis by modulating Claudin6 in Xenopus

Authors:
Wang X, Sun J, Wang Z, Li C, Mao B
Citation:
Biochem Biophys Res Commun. 2020 Mar 25. pii: S0006-291X(20)30590-8. doi: 10.1016/j.bbrc.2020.03.099. [Epub ahead of print]
Epub:
Yes
Abstract:
Receptor tyrosine kinase EphA7 is specifically expressed in otic region in Xenopus early development. However, its role in...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0006291X20305908?via%3Dihub
Organism or Cell Type:
Xenopus
Citation Extract:
Wang X, Sun J, Wang Z, Li C, Mao B. EphA7 is required for otic epithelial homeostasis by modulating Claudin6 in Xenopus. Biochem Biophys Res Commun. 2020 Mar 25. pii: S0006-291X(20)30590-8. doi: 10.1016/j.bbrc.2020.03.099. [Epub ahead of print].

Single-cell chromatin accessibility maps reveal regulatory programs driving early mouse organogenesis

Authors:
Pijuan-Sala B, Wilson NK, Xia J, Hou X, Hannah RL, Kinston S, Calero-Nieto FJ, Olivier Poirion O, Preissl S, Liu F, Göttgens B
Citation:
Nat Cell Biol. 2020;[Epub ahead of print] doi:10.1038/s41556-020-0489-9
Epub:
Yes
Abstract:
During mouse embryonic development, pluripotent cells rapidly divide and diversify, yet the regulatory programs that define the...
Link:
https://www.nature.com/articles/s41556-020-0489-9
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pijuan-Sala B, Wilson NK, Xia J, Hou X, Hannah RL, Kinston S, Calero-Nieto FJ, Olivier Poirion O, Preissl S, Liu F, Göttgens B. Single-cell chromatin accessibility maps reveal regulatory programs driving early mouse organogenesis. Nat Cell Biol. 2020;[Epub ahead of print] doi:10.1038/s41556-020-0489-9.

RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells

Authors:
Santoriello C, Sporrij A, Yang S, Flynn RA, Henriques T, Dorjsuren B, Greig EC, McCall W, Stanhope ME, Fazio M, Superdock M, Lichtig A, Adatto I, Brian J. Abraham BJ, Kalocsay M, Jurynec M, Zhou Y, Adelman K, Calo E, Zon LI
Citation:
Nat Cell Biol. 2020;[Epub ahead of print] doi:10.1038/s41556-020-0493-0
Epub:
Yes
Abstract:
The availability of nucleotides has a direct impact on transcription. The inhibition of dihydroorotate dehydrogenase (DHODH)...
Link:
https://www.nature.com/articles/s41556-020-0493-0
Organism or Cell Type:
zebrafish
Citation Extract:
Santoriello C, Sporrij A, Yang S, Flynn RA, Henriques T, Dorjsuren B, Greig EC, McCall W, Stanhope ME, Fazio M, Superdock M, Lichtig A, Adatto I, Brian J. Abraham BJ, Kalocsay M, Jurynec M, Zhou Y, Adelman K, Calo E, Zon LI. RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells. Nat Cell Biol. 2020;[Epub ahead of print] doi:10.1038/s41556-020-0493-0.

Oocytes mount a noncanonical DNA damage response involving APC-Cdh1–mediated proteolysis

Authors:
Subramanian GN, Greaney J, Wei Z, Becherel O, Lavin M, Homer HA
Citation:
J Cell Biol. 2020;219(4):[Epub ahead of print] doi:10.1083/jcb.201907213
Epub:
Yes
Abstract:
In mitotic cells, DNA damage induces temporary G2 arrest via inhibitory Cdk1 phosphorylation. In contrast, fully grown G2-stage...
Link:
https://rupress.org/jcb/article-abstract/219/4/e201907213/151594/Oocytes-mount-a-noncanonical-DNA-damage-response
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Subramanian GN, Greaney J, Wei Z, Becherel O, Lavin M, Homer HA. Oocytes mount a noncanonical DNA damage response involving APC-Cdh1–mediated proteolysis. J Cell Biol. 2020;219(4):[Epub ahead of print] doi:10.1083/jcb.201907213.

DOCK3 is a dosage-sensitive regulator of skeletal muscle and Duchenne muscular dystrophy-associated pathologies

Authors:
Reid AL, Wang Y, Samani A, Hightower RM, Lopez MA, Shawn R Gilbert, Ianov L, Crossman DK, Italia LJD, Millay DP, van Groen T, Halade GV, Alexander MS
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.03.27.010223
Epub:
Not Epub
Abstract:
DOCK3 is a member of the DOCK family of guanine nucleotide exchange factors that function to regulate cell migration, fusion,...
Link:
https://www.biorxiv.org/content/10.1101/2020.03.27.010223v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Reid AL, Wang Y, Samani A, Hightower RM, Lopez MA, Shawn R Gilbert, Ianov L, Crossman DK, Italia LJD, Millay DP, van Groen T, Halade GV, Alexander MS. DOCK3 is a dosage-sensitive regulator of skeletal muscle and Duchenne muscular dystrophy-associated pathologies. bioRxiv. 2020;[preprint] doi:10.1101/2020.03.27.010223 .

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