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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

The SCF/KIT pathway implements self-organised epithelial patterning by cell movement

Authors:
Chuyen A, Rulquin C, Thome V, Clement R, Kodjabachian L, Pasini A
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.04.22.055483
Epub:
Not Epub
Abstract:
How individual cell behaviours lead to the emergence of global patterns is poorly understood. In the Xenopus embryonic...
Link:
https://www.biorxiv.org/content/10.1101/2020.04.22.055483v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Chuyen A, Rulquin C, Thome V, Clement R, Kodjabachian L, Pasini A. The SCF/KIT pathway implements self-organised epithelial patterning by cell movement. bioRxiv. 2020;[preprint] doi:10.1101/2020.04.22.055483.

Dysregulation of NIPBL leads to impaired RUNX1 expression and haematopoietic defects

Authors:
Mazzola M, Pezzotta A, Fazio G, Rigamonti A, Bresciani E, Gaudenzi G, Pelleri MC, Saitta C, Ferrari L, Parma M, Fumagalli M, Biondi A, Cazzaniga G, Marozzi A, Pistocchi A
Citation:
J Cell Mol Med. 2020 Apr 23. doi: 10.1111/jcmm.15269. [Epub ahead of print]
Epub:
Yes
Abstract:
The transcription factor RUNX1, a pivotal regulator of HSCs and haematopoiesis, is a frequent target of chromosomal...
Link:
https://onlinelibrary.wiley.com/doi/10.1111/jcmm.15269
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mazzola M, Pezzotta A, Fazio G, Rigamonti A, Bresciani E, Gaudenzi G, Pelleri MC, Saitta C, Ferrari L, Parma M, Fumagalli M, Biondi A, Cazzaniga G, Marozzi A, Pistocchi A. Dysregulation of NIPBL leads to impaired RUNX1 expression and haematopoietic defects. J Cell Mol Med. 2020 Apr 23. doi: 10.1111/jcmm.15269. [Epub ahead of print].

Vasohibin-1 mediated tubulin detyrosination selectively regulates secondary sprouting and lymphangiogenesis in the zebrafish trunk

Authors:
de Oliveira MB, Meier K, Coxam B, Geudens I, Jung S, Szymborska A, Gerhardt H
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.04.23.053256
Epub:
Not Epub
Abstract:
Previous studies have shown that Vasohibin-1 (Vash-1) is stimulated by VEGFs in endothelial cells and that its overexpression...
Link:
https://www.biorxiv.org/content/10.1101/2020.04.23.053256v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
de Oliveira MB, Meier K, Coxam B, Geudens I, Jung S, Szymborska A, Gerhardt H. Vasohibin-1 mediated tubulin detyrosination selectively regulates secondary sprouting and lymphangiogenesis in the zebrafish trunk. bioRxiv. 2020;[preprint] doi:10.1101/2020.04.23.053256 .

Rac2 Regulates the Migration of T Lymphoid Progenitors to the Thymus during Zebrafish Embryogenesis

Authors:
Lu X, Zhang Y, Liu F, Wang L
Citation:
J Immunol. 2020;204(9):2447-54. doi:10.4049/jimmunol.1901494
Epub:
Not Epub
Abstract:
The caudal hematopoietic tissue in zebrafish, the equivalent to the fetal liver in mammals, is an intermediate hematopoietic...
Link:
https://www.jimmunol.org/content/204/9/2447
Organism or Cell Type:
zebrafish
Citation Extract:
Lu X, Zhang Y, Liu F, Wang L. Rac2 Regulates the Migration of T Lymphoid Progenitors to the Thymus during Zebrafish Embryogenesis. J Immunol. 2020;204(9):2447-54. doi:10.4049/jimmunol.1901494.

Role of the ADCY9 gene in cardiac abnormalities of the Rubinstein-Taybi syndrome

Authors:
Wu Y, Xia Y, Li P, Qu H-Q, Liu Y, Yang Y, Lin J, Zheng M, Tian L, Wu Z, Huang S, Qin X, Zhou X, Chen S, Liu Y, Wang Y, Li X, Zeng H, Hakonarson H, Zhuang J
Citation:
Orphanet J Rare Dis. 2020;15(1):101. doi:10.1186/s13023-020-01378-9
Epub:
Not Epub
Abstract:
Background: Rubinstein–Taybi syndrome (RTS) is a rare, congenital, plurimalformative, and neurodevelopmental disorder. Previous...
Link:
https://ojrd.biomedcentral.com/articles/10.1186/s13023-020-01378-9
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu Y, Xia Y, Li P, Qu H-Q, Liu Y, Yang Y, Lin J, Zheng M, Tian L, Wu Z, Huang S, Qin X, Zhou X, Chen S, Liu Y, Wang Y, Li X, Zeng H, Hakonarson H, Zhuang J. Role of the ADCY9 gene in cardiac abnormalities of the Rubinstein-Taybi syndrome. Orphanet J Rare Dis. 2020;15(1):101. doi:10.1186/s13023-020-01378-9.

Zebrafish ambra1a and ambra1b Silencing Affect Heart Development

Authors:
Meneghetti G, Skobo T, Chrisam M, Fontana CM, Facchinello N, Nazio F, Cecconi F, Bonaldo P, Dalla Valle L
Citation:
Zebrafish. 2020 Apr 22. doi: 10.1089/zeb.2020.1860. [Epub ahead of print]
Epub:
Yes
Abstract:
In zebrafish, two paralogous genes, activating molecule in beclin-1 (BECN1)-regulated autophagy ambra1a and ambra1b, both...
Link:
https://www.liebertpub.com/doi/abs/10.1089/zeb.2020.1860
Citation Extract:
Meneghetti G, Skobo T, Chrisam M, Fontana CM, Facchinello N, Nazio F, Cecconi F, Bonaldo P, Dalla Valle L. Zebrafish ambra1a and ambra1b Silencing Affect Heart Development. Zebrafish. 2020 Apr 22. doi: 10.1089/zeb.2020.1860. [Epub ahead of print].

Twist3 is required for dedifferentiation during extraocular muscle regeneration in adult zebrafish

Authors:
Zhao Y, Louie KW, Tingle CF, Sha C, Heisel CJ, Unsworth SP, Kish PE, Kahana A
Citation:
PLoS ONE. 2020;15(4):e0231963. doi:10.1371/journal.pone.0231963
Epub:
Not Epub
Abstract:
Severely damaged adult zebrafish extraocular muscles (EOMs) regenerate through dedifferentiation of residual myocytes involving...
Link:
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0231963
Delivery Method:
injection then electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao Y, Louie KW, Tingle CF, Sha C, Heisel CJ, Unsworth SP, Kish PE, Kahana A. Twist3 is required for dedifferentiation during extraocular muscle regeneration in adult zebrafish. PLoS ONE. 2020;15(4):e0231963. doi:10.1371/journal.pone.0231963.

Functional partitioning of a liquid-like organelle during assembly of axonemal dyneins

Authors:
Lee C, Cox R, Papoulas O, Horani A, Drew K, Devitt C, Brody SL, Marcotte E, Wallingford JB
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.04.21.052837
Epub:
Not Epub
Abstract:
Ciliary motility is driven by axonemal dyneins that are assembled in the cytoplasm before deployment to cilia. Motile...
Link:
https://www.biorxiv.org/content/10.1101/2020.04.21.052837v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Lee C, Cox R, Papoulas O, Horani A, Drew K, Devitt C, Brody SL, Marcotte E, Wallingford JB. Functional partitioning of a liquid-like organelle during assembly of axonemal dyneins. bioRxiv. 2020;[preprint] doi:10.1101/2020.04.21.052837.

Developmental and Tumor Angiogenesis Requires the Mitochondria-Shaping Protein Opa1

Authors:
Herkenne S, Ek O, Zamberlan M, Pellattiero A, Chergova M, Chivite I, Novotná E, Rigoni G, Fonseca TB, Samardzic D, Agnellini A, Bean C, Di Benedetto G, Tiso N, Argenton F, Viola A, Soriano ME, Giacomello M, Ziviani E, Sales G, Claret M, Graupera M, Scorrano L
Citation:
Cell Metab. 2020 Apr 17. pii: S1550-4131(20)30189-3. doi: 10.1016/j.cmet.2020.04.007. [Epub ahead of print]
Epub:
Yes
Abstract:
While endothelial cell (EC) function is influenced by mitochondrial metabolism, the role of mitochondrial dynamics in...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S1550413120301893
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Herkenne S, Ek O, Zamberlan M, Pellattiero A, Chergova M, Chivite I, Novotná E, Rigoni G, Fonseca TB, Samardzic D, Agnellini A, Bean C, Di Benedetto G, Tiso N, Argenton F, Viola A, Soriano ME, Giacomello M, Ziviani E, Sales G, Claret M, Graupera M, Scorrano L. Developmental and Tumor Angiogenesis Requires the Mitochondria-Shaping Protein Opa1. Cell Metab. 2020 Apr 17. pii: S1550-4131(20)30189-3. doi: 10.1016/j.cmet.2020.04.007. [Epub ahead of print].

Antisense targeting of decoy exons can reduce intron retention and increase protein expression in human erythroblasts

Authors:
Parra MK, Zhang W, Vu J, DeWitt MA, Conboy JG
Citation:
RNA. 2020 Apr 20. pii: rna.075028.120. doi: 10.1261/rna.075028.120. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The decoy exon model has been proposed to regulate a subset of intron retention (IR) events involving predominantly larger...
Link:
https://rnajournal.cshlp.org/content/early/2020/04/20/rna.075028.120.abstract
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: human erythroblasts
Citation Extract:
Parra MK, Zhang W, Vu J, DeWitt MA, Conboy JG. Antisense targeting of decoy exons can reduce intron retention and increase protein expression in human erythroblasts. RNA. 2020 Apr 20. pii: rna.075028.120. doi: 10.1261/rna.075028.120. [Epub ahead of print].

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