You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Human-specific staphylococcal virulence factors enhance pathogenicity in a humanised zebrafish C5a receptor model

Authors:
Buchan KD, van Gent M, Prajsnar TK, Ogryzko NV, de Jong NWM, Kolata J, Foster SJ, van Strijp JAG, Renshaw SA
Citation:
bioRxiv. 2020; doi:10.1101/2020.02.18.955021
Epub:
Not Epub
Abstract:
Staphylococcus aureus infects approximately 30% of the human population and causes a spectrum of pathologies ranging from mild...
Link:
https://www.biorxiv.org/content/10.1101/2020.02.18.955021v2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Buchan KD, van Gent M, Prajsnar TK, Ogryzko NV, de Jong NWM, Kolata J, Foster SJ, van Strijp JAG, Renshaw SA. Human-specific staphylococcal virulence factors enhance pathogenicity in a humanised zebrafish C5a receptor model. bioRxiv. 2020; doi:10.1101/2020.02.18.955021 .

The buds of Oscarella lobularis (Porifera): a new convenient model for sponge cell and developmental biology

Authors:
Rocher C, Vernale A, Fierro-Constain L, Sejourne N, Chenesseau S, Marschal C, Le Golf E, Dutilleul M, Matthews C, Marschal F, Brouilly N, Massey-Harroche D, Ereskovsky A, Le Bivic A, Borchiellini C, Renard E
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.06.23.167296
Epub:
Not Epub
Abstract:
The comparative study of the four non-bilaterian phyla (Cnidaria, Placozoa, Ctenophora, Porifera) should provide insights into...
Link:
https://www.biorxiv.org/content/10.1101/2020.06.23.167296v1
Delivery Method:
bathing, Endo-Porter
Organism or Cell Type:
Oscarella lobularis (Porifera)
Citation Extract:
Rocher C, Vernale A, Fierro-Constain L, Sejourne N, Chenesseau S, Marschal C, Le Golf E, Dutilleul M, Matthews C, Marschal F, Brouilly N, Massey-Harroche D, Ereskovsky A, Le Bivic A, Borchiellini C, Renard E. The buds of Oscarella lobularis (Porifera): a new convenient model for sponge cell and developmental biology. bioRxiv. 2020;[preprint] doi:10.1101/2020.06.23.167296 .

Histone H3.3 Hira chaperone complex contributes to zygote formation in mice and humans

Authors:
Smith R, Pickering S, Kopakaki A, Thong KJ, Anderson RA, Lin C-J
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.06.18.159954
Epub:
Not Epub
Abstract:
Elucidating the underlining mechanisms underpinning successful fertilisation is imperative in optimising IVF treatments, and...
Link:
https://www.biorxiv.org/content/10.1101/2020.06.18.159954v1
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Smith R, Pickering S, Kopakaki A, Thong KJ, Anderson RA, Lin C-J. Histone H3.3 Hira chaperone complex contributes to zygote formation in mice and humans. bioRxiv. 2020;[preprint] doi:10.1101/2020.06.18.159954 .

The neurodevelopmental disorder risk gene DYRK1A is required for ciliogenesis and control of brain size in Xenopus embryos

Authors:
Willsey HR, Xu Y, Everitt A, Dea J, Exner CRT, Willsey AJ, State MW, Harland RM
Citation:
Development. 2020 Jun 22;147(21):dev189290. doi: 10.1242/dev.189290
Epub:
Not Epub
Abstract:
DYRK1A [dual specificity tyrosine-(Y)-phosphorylation-regulated kinase 1 A] is a high-confidence autism risk gene that encodes...
Link:
https://dev.biologists.org/content/147/21/dev189290
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Willsey HR, Xu Y, Everitt A, Dea J, Exner CRT, Willsey AJ, State MW, Harland RM. The neurodevelopmental disorder risk gene DYRK1A is required for ciliogenesis and control of brain size in Xenopus embryos. Development. 2020 Jun 22;147(21):dev189290. doi: 10.1242/dev.189290.

Toll-like receptor 4 is activated by platinum and contributes to cisplatin-induced ototoxicity

Authors:
Babolmorad G, Latif A, Pollock NM, Domingo IK, Delyea C, Rieger AM, Allison WT, Bhavsar AP
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.06.19.162057
Epub:
Not Epub
Abstract:
Toll-like receptor 4 (TLR4) is famous for recognizing the bacterial endotoxin lipopolysaccharide (LPS) as its canonical ligand...
Link:
https://www.biorxiv.org/content/10.1101/2020.06.19.162057v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Babolmorad G, Latif A, Pollock NM, Domingo IK, Delyea C, Rieger AM, Allison WT, Bhavsar AP. Toll-like receptor 4 is activated by platinum and contributes to cisplatin-induced ototoxicity. bioRxiv. 2020;[preprint] doi:10.1101/2020.06.19.162057.

SPIN90 associates with mDia1 and the Arp2/3 complex to regulate cortical actin organization

Authors:
Cao L, Yonis A, Vaghela M, Barriga EH, Chugh P, Smith MB, Maufront J, Lavoie G, Méant A, Ferber E, Bovellan M, Alberts A, Bertin A, Mayor R, Paluch EK, Roux PP, Jégou A, Romet-Lemonne G, Charras G
Citation:
Nat Cell Biol. 2020:[Epub ahead of print] doi:10.1038/s41556-020-0531-y
Epub:
Yes
Abstract:
Cell shape is controlled by the submembranous cortex, an actomyosin network mainly generated by two actin nucleators: the Arp2/...
Link:
https://www.nature.com/articles/s41556-020-0531-y
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Cao L, Yonis A, Vaghela M, Barriga EH, Chugh P, Smith MB, Maufront J, Lavoie G, Méant A, Ferber E, Bovellan M, Alberts A, Bertin A, Mayor R, Paluch EK, Roux PP, Jégou A, Romet-Lemonne G, Charras G. SPIN90 associates with mDia1 and the Arp2/3 complex to regulate cortical actin organization. Nat Cell Biol. 2020:[Epub ahead of print] doi:10.1038/s41556-020-0531-y.

Pervasive changes of mRNA splicing in upf1-deficient zebrafish identify rpl10a as a regulator of T cell development

Authors:
Lawir DF, Sikora K, O'Meara CP, Schorpp M, Boehm T
Citation:
Proc Natl Acad Sci U S A. 2020 Jun 22:201917812 [Epub ahead of print]. doi:10.1073/pnas.1917812117
Epub:
Yes
Abstract:
The transcriptome of eukaryotic cells is constantly monitored for errors to avoid the production of undesired protein variants...
Link:
https://www.pnas.org/content/early/2020/06/17/1917812117
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lawir DF, Sikora K, O'Meara CP, Schorpp M, Boehm T. Pervasive changes of mRNA splicing in upf1-deficient zebrafish identify rpl10a as a regulator of T cell development. Proc Natl Acad Sci U S A. 2020 Jun 22:201917812 [Epub ahead of print]. doi:10.1073/pnas.1917812117.

Drainage of inflammatory macromolecules from brain to periphery targets the liver for macrophage infiltration

Authors:
Yang L, Jiménez JA, Earley AM, Hamlin V, Kwon V, Dixon CT, Shiau CE
Citation:
bioRxiv;[preprint] doi:10.1101/2020.06.18.159392
Epub:
Not Epub
Abstract:
Many brain pathologies are associated with liver damage, but a direct link has long remained elusive. Here, we establish a new...
Link:
https://www.biorxiv.org/content/10.1101/2020.06.18.159392v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yang L, Jiménez JA, Earley AM, Hamlin V, Kwon V, Dixon CT, Shiau CE. Drainage of inflammatory macromolecules from brain to periphery targets the liver for macrophage infiltration. bioRxiv;[preprint] doi:10.1101/2020.06.18.159392.

Cell stemness is maintained upon concurrent expression of RB and the mitochondrial ribosomal protein S18-2

Authors:
Mushtaq M, Kovalevska L, Darekar S, Abramsson A, Zetterberg H, Kashuba V, Klein G, Arsenian-Henriksson M, Kashuba E
Citation:
Proc Natl Acad Sci U S A. 2020:201922535 [Epub ahead of print] . doi: 10.1073/pnas.1922535117
Epub:
Yes
Abstract:
Stemness encompasses the capability of a cell for self-renewal and differentiation. The stem cell maintains a balance between...
Link:
https://www.pnas.org/content/early/2020/06/19/1922535117
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mushtaq M, Kovalevska L, Darekar S, Abramsson A, Zetterberg H, Kashuba V, Klein G, Arsenian-Henriksson M, Kashuba E. Cell stemness is maintained upon concurrent expression of RB and the mitochondrial ribosomal protein S18-2. Proc Natl Acad Sci U S A. 2020:201922535 [Epub ahead of print] . doi: 10.1073/pnas.1922535117.

WDR34 mutation from anencephaly patients impaired both SHH and PCP signaling pathways

Authors:
Yin H, Peng R, Chen Z, Wang H, Zhang T, Zheng Y
Citation:
J Hum Genet. 2020;[Epub ahead of print] doi:10.1038/s10038-020-0793-z
Epub:
Yes
Abstract:
Neural tube defects (NTDs) are debilitating human congenital abnormalities due to failure of neural tube closure. Sonic...
Link:
https://www.nature.com/articles/s10038-020-0793-z
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yin H, Peng R, Chen Z, Wang H, Zhang T, Zheng Y. WDR34 mutation from anencephaly patients impaired both SHH and PCP signaling pathways. J Hum Genet. 2020;[Epub ahead of print] doi:10.1038/s10038-020-0793-z.

Pages