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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12483 scientific papers returned from the database with the search filters currently being used below.

Paired Box 9 (PAX9), the RNA polymerase II transcription factor, regulates human ribosome biogenesis and craniofacial development

Authors:
Farley-Barnes KI, Deniz E, Overton MM, Khokha MK, Baserga SJ
Citation:
PLoS Genet. 2020;16(8):e1008967. doi:10.1371/journal.pgen.1008967
Epub:
Not Epub
Abstract:
Dysregulation of ribosome production can lead to a number of developmental disorders called ribosomopathies. Despite the...
Link:
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1008967
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Farley-Barnes KI, Deniz E, Overton MM, Khokha MK, Baserga SJ. Paired Box 9 (PAX9), the RNA polymerase II transcription factor, regulates human ribosome biogenesis and craniofacial development. PLoS Genet. 2020;16(8):e1008967. doi:10.1371/journal.pgen.1008967.

In Vivo Monitoring of Carbonic Anhydrases Expression on Growth of Larval Zebrafish: A New Environment-Sensitive Fluorophore for Responsive Turn-On Fluorescence

Authors:
Chou C-H, Wu C-Y, Chen C-L, Zhou J-Q, Kao Y-C, Chen H-Y, Lin P-C
Citation:
Chem Comm. 2020;[Epub ahead pf print] doi:10.1039/D0CC03090B
Epub:
Yes
Abstract:
This study monitors dynamic progress of newly developed background-free, target responsive strategy; 2,3-dihydroquinolin-4-...
Link:
https://pubs.rsc.org/en/content/articlelanding/2020/cc/d0cc03090b
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chou C-H, Wu C-Y, Chen C-L, Zhou J-Q, Kao Y-C, Chen H-Y, Lin P-C. In Vivo Monitoring of Carbonic Anhydrases Expression on Growth of Larval Zebrafish: A New Environment-Sensitive Fluorophore for Responsive Turn-On Fluorescence. Chem Comm. 2020;[Epub ahead pf print] doi:10.1039/D0CC03090B.

The Joubert Syndrome Gene arl13b is Critical for Early Cerebellar Development in Zebrafish

Authors:
Zhu J, Wang HT, Chen YR, Yan LY, Han YY, Liu LY, Cao Y, Liu ZZ, Xu HA
Citation:
Neurosci Bull. 2020 Aug 18. doi: 10.1007/s12264-020-00554-y. Online ahead of print.
Epub:
Yes
Abstract:
Joubert syndrome is characterized by unique malformation of the cerebellar vermis. More than thirty Joubert syndrome genes have...
Link:
https://link.springer.com/article/10.1007%2Fs12264-020-00554-y
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhu J, Wang HT, Chen YR, Yan LY, Han YY, Liu LY, Cao Y, Liu ZZ, Xu HA. The Joubert Syndrome Gene arl13b is Critical for Early Cerebellar Development in Zebrafish. Neurosci Bull. 2020 Aug 18. doi: 10.1007/s12264-020-00554-y. Online ahead of print..

Live-imaging of endothelial Erk activity reveals dynamic and sequential signalling events during regenerative angiogenesis

Authors:
Okuda K, Keyser M, Gurevich DB, Sturtzel C, Paterson S, Chen H, Scott M, Condon N, Martin PB, Distel M, Hogan BM
Citation:
bioRxiv 2020;[preprint] doi:10.1101/2020.08.17.254912
Epub:
Not Epub
Abstract:
The formation of new blood vessel networks occurs via angiogenesis during development, tissue repair and disease. Angiogenesis...
Link:
https://www.biorxiv.org/content/10.1101/2020.08.17.254912v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Okuda K, Keyser M, Gurevich DB, Sturtzel C, Paterson S, Chen H, Scott M, Condon N, Martin PB, Distel M, Hogan BM. Live-imaging of endothelial Erk activity reveals dynamic and sequential signalling events during regenerative angiogenesis. bioRxiv 2020;[preprint] doi:10.1101/2020.08.17.254912.

Production of common carp donor-derived offspring from goldfish surrogate broodstock

Authors:
Franěk R, Kašpar V, Gela D, Pšenička M
Citation:
Research Square. 2020:[preprint] doi:10.21203/rs.3.rs-57467/v1+
Epub:
Not Epub
Abstract:
Background: Common carp is the fourth most-produced species in worldwide aquaculture. Significant efforts are invested in...
Link:
https://www.researchsquare.com/article/rs-57467/v1
Delivery Method:
microinjection
Organism or Cell Type:
Carassius auratus (goldfish)
Citation Extract:
Franěk R, Kašpar V, Gela D, Pšenička M. Production of common carp donor-derived offspring from goldfish surrogate broodstock. Research Square. 2020:[preprint] doi:10.21203/rs.3.rs-57467/v1+.

Intrinsic Endocardial Defects Contribute to Hypoplastic Left Heart Syndrome

Authors:
Miao Y, Tian L, Martin M, Paige SL, Galdos FX, Li J, Klein A, Zhang H, Ma N, Wei Y, Stewart M, Lee S, Moonen J-R, Zhang B, Grossfeld P, Mital S, Chitayat D, Wu JC, Rabinovitch M, Nelson TJ, Nie S, Wu SM, Gu M
Citation:
Cell Stem Cell. 2020;[Epub ahead of print] doi:10.1016/j.stem.2020.07.015
Epub:
Not Epub
Abstract:
Hypoplastic left heart syndrome (HLHS) is a complex congenital heart disease characterized by abnormalities in the left...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S1934590920303532
Delivery Method:
injection
Organism or Cell Type:
Xenopus
Citation Extract:
Miao Y, Tian L, Martin M, Paige SL, Galdos FX, Li J, Klein A, Zhang H, Ma N, Wei Y, Stewart M, Lee S, Moonen J-R, Zhang B, Grossfeld P, Mital S, Chitayat D, Wu JC, Rabinovitch M, Nelson TJ, Nie S, Wu SM, Gu M. Intrinsic Endocardial Defects Contribute to Hypoplastic Left Heart Syndrome. Cell Stem Cell. 2020;[Epub ahead of print] doi:10.1016/j.stem.2020.07.015.

Proteolytic Restriction of Chordin Range Underlies BMP Gradient Formation

Authors:
Tuazon FB, Wang X, Andrade JL, Umulis D, Mullins MC
Citation:
Cell Rep. 2020;32(7):108039. doi:10.1016/j.celrep.2020.108039
Epub:
Not Epub
Abstract:
A fundamental question in developmental biology is how morphogens, such as bone morphogenetic protein (BMP), form precise...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(20)31024-X
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tuazon FB, Wang X, Andrade JL, Umulis D, Mullins MC. Proteolytic Restriction of Chordin Range Underlies BMP Gradient Formation. Cell Rep. 2020;32(7):108039. doi:10.1016/j.celrep.2020.108039.

In-depth analysis reveals complex molecular etiology of idiopathic cerebral palsy

Authors:
Li N, Zhou P, Tang H, He L, Fang X, Zhao J, Wang X, Qi Y, Sun C, Lin Y, Qin F, Yang M, Zhang Z, Liao C, Zheng S, Peng X, Xue T, Zhu Q, Li Y, Liu L, Huang J, Liu L, Peng C, Han D, Liu D, Xu K, Hu H(C)
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.17.255158
Epub:
Not Epub
Abstract:
Cerebral palsy (CP), the most prevalent physical disability in children, has long been ignored with regard to its inherent...
Link:
https://www.biorxiv.org/content/10.1101/2020.08.17.255158v1.full.pdf
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li N, Zhou P, Tang H, He L, Fang X, Zhao J, Wang X, Qi Y, Sun C, Lin Y, Qin F, Yang M, Zhang Z, Liao C, Zheng S, Peng X, Xue T, Zhu Q, Li Y, Liu L, Huang J, Liu L, Peng C, Han D, Liu D, Xu K, Hu H(C). In-depth analysis reveals complex molecular etiology of idiopathic cerebral palsy. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.17.255158.

Knockout of SORBS2 Protein Disrupts the Structural Integrity of Intercalated Disc and Manifests Features of Arrhythmogenic Cardiomyopathy

Authors:
Ding Y, Yang J, Chen P, Lu T, Jiao K, Tester DJ, Giudicessi JR, Jiang K, Ackerman MJ, Li Y, Wang DW, Lee HC, Wang DW, Xu X
Citation:
J Am Heart Assoc. 2020 Aug 18:e017055. doi:10.1161/JAHA.119.017055. Online ahead of print
Epub:
Yes
Abstract:
Background Sorbs2b (sorbin and SH3 domain-containing 2b) was recently identified as a cardiomyopathy gene from a zebrafish...
Link:
https://www.ahajournals.org/doi/10.1161/JAHA.119.017055
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ding Y, Yang J, Chen P, Lu T, Jiao K, Tester DJ, Giudicessi JR, Jiang K, Ackerman MJ, Li Y, Wang DW, Lee HC, Wang DW, Xu X. Knockout of SORBS2 Protein Disrupts the Structural Integrity of Intercalated Disc and Manifests Features of Arrhythmogenic Cardiomyopathy. J Am Heart Assoc. 2020 Aug 18:e017055. doi:10.1161/JAHA.119.017055. Online ahead of print.

The tolerance to hypoxia is defined by a time-sensitive response of the gene regulatory network in sea urchin embryos

Authors:
Layous M, Khalaily L, Gildor T, de-Leon SB-T
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.09.242933
Epub:
Not Epub
Abstract:
Deoxygenation, the reduction of oxygen level in the oceans induced by global warming and anthropogenic disturbances, is a major...
Link:
https://www.biorxiv.org/content/10.1101/2020.08.09.242933v2
Delivery Method:
microinjection
Organism or Cell Type:
Paracentrotus lividus (sea urchin)
Citation Extract:
Layous M, Khalaily L, Gildor T, de-Leon SB-T. The tolerance to hypoxia is defined by a time-sensitive response of the gene regulatory network in sea urchin embryos. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.09.242933 .

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