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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

T-Cell Factor 4 (tcf7l2) Is the Main Effector of Wnt Signaling During Zebrafish Intestine Organogenesis

Authors:
Faro A, Boj SF, Ambrósio R, van den Broek O, Korving J, Clevers H
Citation:
Zebrafish. 2009 Mar;6(1):59-68
Epub:
Not Epub
Abstract:
Abstract The Wnt pathway orchestrates cell fate decisions during embryonic development, organogenesis, and adult tissues...
Organism or Cell Type:
zebrafish
Citation Extract:
Faro A, Boj SF, Ambrósio R, van den Broek O, Korving J, Clevers H. T-Cell Factor 4 (tcf7l2) Is the Main Effector of Wnt Signaling During Zebrafish Intestine Organogenesis. Zebrafish. 2009 Mar;6(1):59-68.

Tailbud-derived Bmp4 drives proliferation and inhibits maturation of zebrafish chordamesoderm

Authors:
Esterberg R, Delalande JM, Fritz A
Citation:
Development. 2008 Dec;135(23):3891-901. Epub 2008 Oct 23
Epub:
Not Epub
Abstract:
In zebrafish, BMP signaling establishes cell identity along the dorsoventral (DV) axis during gastrulation. Owing to the early...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Esterberg R, Delalande JM, Fritz A. Tailbud-derived Bmp4 drives proliferation and inhibits maturation of zebrafish chordamesoderm. Development. 2008 Dec;135(23):3891-901. Epub 2008 Oct 23.

The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) pathway regulates developmental cerebral-vascular stability via prenylation-dependent signalling pathway

Authors:
Eisa-Beygi S, Hatch G, Noble S, Ekker M, Moon TW
Citation:
Dev Biol. 2012 Nov 30. doi:pii: S0012-1606(12)00643-4. 10.1016/j.ydbio.2012.11.024. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Spontaneous intracranial hemorrhage is a debilitating form of stroke, often leading to death or permanent cognitive impairment...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Eisa-Beygi S, Hatch G, Noble S, Ekker M, Moon TW. The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) pathway regulates developmental cerebral-vascular stability via prenylation-dependent signalling pathway. Dev Biol. 2012 Nov 30. doi:pii: S0012-1606(12)00643-4. 10.1016/j.ydbio.2012.11.024. [Epub ahead of print].

The adenomatous polyposis coli tumor suppressor gene regulates expression of cyclooxygenase-2 by a mechanism that involves retinoic acid

Authors:
Eisinger AL, Nadauld LD, Shelton DN, Peterson PW, Phelps RA, Chidester S, Stafforini DM, Prescott SM, Jones DA
Citation:
J Biol Chem. 2006 Jul 21;281(29):20474-82. Epub 2006 May 14
Epub:
Not Epub
Abstract:
Mutations in the adenomatous polyposis coli (APC) gene result in uncontrolled proliferation of intestinal epithelial cells and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Eisinger AL, Nadauld LD, Shelton DN, Peterson PW, Phelps RA, Chidester S, Stafforini DM, Prescott SM, Jones DA. The adenomatous polyposis coli tumor suppressor gene regulates expression of cyclooxygenase-2 by a mechanism that involves retinoic acid. J Biol Chem. 2006 Jul 21;281(29):20474-82. Epub 2006 May 14.

The Amot/Patj/Syx signalling complex spatially controls RhoA GTPase activity in migrating endothelial cells

Authors:
Ernkvist M, Luna Persson N, Audebert S, Lecine P, Sinha I, Liu M, Schlueter M, Horowitz A, Aase K, Weide T, Borg JP, Majumdar A, Holmgren L
Citation:
Blood. 2008 Sep 29. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Controlled regulation of Rho GTPase activity is an essential component mediating growth factor stimulated migration. We have...
Organism or Cell Type:
zebrafish
Citation Extract:
Ernkvist M, Luna Persson N, Audebert S, Lecine P, Sinha I, Liu M, Schlueter M, Horowitz A, Aase K, Weide T, Borg JP, Majumdar A, Holmgren L. The Amot/Patj/Syx signalling complex spatially controls RhoA GTPase activity in migrating endothelial cells. Blood. 2008 Sep 29. [Epub ahead of print].

The autism susceptibility gene met regulates zebrafish cerebellar development and facial motor neuron migration

Authors:
Elsen GE, Choi LY, Prince VE, Ho RK
Citation:
Dev Biol. 2009 Sep 2. [Epub ahead of print]
Epub:
Not Epub
Abstract:
During development, Met signaling regulates a range of cellular processes including growth, differentiation, survival and...
Organism or Cell Type:
zebrafish
Citation Extract:
Elsen GE, Choi LY, Prince VE, Ho RK. The autism susceptibility gene met regulates zebrafish cerebellar development and facial motor neuron migration. Dev Biol. 2009 Sep 2. [Epub ahead of print].

The DSCR1 (Adapt78) isoform 1 protein calcipressin 1 inhibits calcineurin and protects against acute calcium-mediated stress damage, including transient oxidative stress

Authors:
Ermak G, Harris CD, Davies KJ.
Citation:
FASEB J. 2002 Jun;16(8):814-24
Epub:
Not Epub
Abstract:
Although DSCR1 (Adapt78) has been associated with successful adaptation to oxidative stress and calcium stress and with...
Delivery Method:
Scrape Delivery
Organism or Cell Type:
cell culture: PC12 cells
Citation Extract:
Ermak G, Harris CD, Davies KJ.. The DSCR1 (Adapt78) isoform 1 protein calcipressin 1 inhibits calcineurin and protects against acute calcium-mediated stress damage, including transient oxidative stress. FASEB J. 2002 Jun;16(8):814-24.

The homeodomain factor Xanf represses expression of genes in the presumptive rostral forebrain that specify more caudal brain regions

Authors:
Ermakova GV, Solovieva EA, Martynova NY, Zaraisky AG
Citation:
Dev Biol. 2007 Jul 15;307(2):483-97. Epub 2007 Apr 5.
Epub:
Not Epub
Abstract:
Early development of the rostral forebrain (RF) in vertebrates is accompanied by the inhibition of two homeobox regulators,...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ermakova GV, Solovieva EA, Martynova NY, Zaraisky AG. The homeodomain factor Xanf represses expression of genes in the presumptive rostral forebrain that specify more caudal brain regions. Dev Biol. 2007 Jul 15;307(2):483-97. Epub 2007 Apr 5..

The Kinase SGK1 in the Endoderm and Mesoderm Promotes Ectodermal Survival by Down-Regulating Components of the Death-Inducing Signaling Complex

Authors:
Endo T, Kusakabe M, Sunadome K, Yamamoto T, Nishida E
Citation:
Sci. Signal. 2011;4,ra2
Epub:
Not Epub
Abstract:
A balance between cell survival and apoptosis is essential for animal development. Although proper development involves...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Endo T, Kusakabe M, Sunadome K, Yamamoto T, Nishida E. The Kinase SGK1 in the Endoderm and Mesoderm Promotes Ectodermal Survival by Down-Regulating Components of the Death-Inducing Signaling Complex. Sci. Signal. 2011;4,ra2.

The Rac1 Regulator ELMO1 Controls Vascular Morphogenesis in Zebrafish

Authors:
Epting D, Wendik B, Bennewitz K, Dietz CT, Driever W, Kroll J
Citation:
Circ Res. 2010 Jul 9;107(1):45-55. doi: 10.1161/CIRCRESAHA.109.213983. Epub 2010 May 13
Epub:
Not Epub
Abstract:
Rationale: Angiogenesis is regulated by the small GTPase Rac1. The ELMO1/DOCK180 complex forms a guanine nucleotide exchange...
Organism or Cell Type:
zebrafish
Citation Extract:
Epting D, Wendik B, Bennewitz K, Dietz CT, Driever W, Kroll J. The Rac1 Regulator ELMO1 Controls Vascular Morphogenesis in Zebrafish. Circ Res. 2010 Jul 9;107(1):45-55. doi: 10.1161/CIRCRESAHA.109.213983. Epub 2010 May 13.

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