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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Growth Arrest Specific 8 (Gas8) and G protein-coupled receptor kinase 2 (GRK2) cooperate in the control of Smoothened signaling

Authors:
Evron T, Philipp M, Lu J, Meloni AR, Burkhalter M, Chen W, Caron MG
Citation:
J Biol Chem. 2011 Aug 5;286(31):27676-86. Epub 2011 Jun 8
Epub:
Not Epub
Abstract:
The G protein-coupled receptor (GPCR)-like molecule Smoothened (Smo) undergoes dynamic intracellular trafficking modulated by...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Evron T, Philipp M, Lu J, Meloni AR, Burkhalter M, Chen W, Caron MG. Growth Arrest Specific 8 (Gas8) and G protein-coupled receptor kinase 2 (GRK2) cooperate in the control of Smoothened signaling. J Biol Chem. 2011 Aug 5;286(31):27676-86. Epub 2011 Jun 8.

Heat shock factor 1 is required for constitutive Hsp70 expression and normal lens development in embryonic zebrafish

Authors:
Evans TG, Belak Z, Ovsenek N, Krone PH
Citation:
Comp Biochem Physiol A Mol Integr Physiol. 2007 Jan;146(1):131-40. Epub 2006 Oct 6.
Epub:
Not Epub
Abstract:
Heat shock factors (HSFs) are the major transcription factors responsible for heat-induced upregulation of heat shock protein (...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Evans TG, Belak Z, Ovsenek N, Krone PH. Heat shock factor 1 is required for constitutive Hsp70 expression and normal lens development in embryonic zebrafish. Comp Biochem Physiol A Mol Integr Physiol. 2007 Jan;146(1):131-40. Epub 2006 Oct 6..

Hes4 Controls Proliferative Properties of Neural Stem Cells During Retinal Ontogenesis

Authors:
El Yakoubi W, Borday C, Hamdache J, Parain K, Tran HT, Vleminckx K, Perron M, Locker M
Citation:
Stem Cells. 2012 Dec;30(12):2784-95. doi: 10.1002/stem.1231.
Epub:
Not Epub
Abstract:
The retina of fish and amphibian contains genuine neural stem cells located at the most peripheral edge of the ciliary marginal...
Delivery Method:
Injection
Organism or Cell Type:
Xenopus
Citation Extract:
El Yakoubi W, Borday C, Hamdache J, Parain K, Tran HT, Vleminckx K, Perron M, Locker M. Hes4 Controls Proliferative Properties of Neural Stem Cells During Retinal Ontogenesis. Stem Cells. 2012 Dec;30(12):2784-95. doi: 10.1002/stem.1231..

Histone deacetylase 3 (hdac3) is specifically required for liver development in zebrafish

Authors:
Farooq M, Sulochana KN, Pan X, To J, Sheng D, Gong Z, Ge R
Citation:
Dev Biol. 2008 May 1;317(1):336-53. Epub 2008 Feb 29.
Epub:
Not Epub
Abstract:
Histone deacetylases (HDACs) are key transcription regulators that function by deacetylating histones/transcription factors and...
Organism or Cell Type:
zebrafish
Citation Extract:
Farooq M, Sulochana KN, Pan X, To J, Sheng D, Gong Z, Ge R. Histone deacetylase 3 (hdac3) is specifically required for liver development in zebrafish. Dev Biol. 2008 May 1;317(1):336-53. Epub 2008 Feb 29..

HMGB1 Contributes to Regeneration After Spinal Cord Injury in Adult Zebrafish

Authors:
Fang P, Pan HC, Lin SL, Zhang WQ, Rauvala H, Schachner M, Shen YQ
Citation:
Mol Neurobiol. 2013 Aug 31. [Epub ahead of print]
Epub:
Not Epub
Abstract:
High mobility group box 1 (HMGB1, also called amphoterin) facilitates neurite outgrowth in early development, yet can...
Organism or Cell Type:
zebrafish
Citation Extract:
Fang P, Pan HC, Lin SL, Zhang WQ, Rauvala H, Schachner M, Shen YQ. HMGB1 Contributes to Regeneration After Spinal Cord Injury in Adult Zebrafish. Mol Neurobiol. 2013 Aug 31. [Epub ahead of print].

Hydroxyproline-based DNA mimics provide an efficient gene silencing in vitro and in vivo

Authors:
Efimov VA, Birikh KR, Staroverov DB, Lukyanov SA, Tereshina MB, Zaraisky AG, Chakhmakhcheva OG
Citation:
Nucleic Acids Res. 2006 May 2;34(8):2247-57. Print 2006.
Epub:
Not Epub
Abstract:
To be effective, antisense molecules should be stable in biological fluids, non-toxic, form stable and specific duplexes with...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Efimov VA, Birikh KR, Staroverov DB, Lukyanov SA, Tereshina MB, Zaraisky AG, Chakhmakhcheva OG. Hydroxyproline-based DNA mimics provide an efficient gene silencing in vitro and in vivo. Nucleic Acids Res. 2006 May 2;34(8):2247-57. Print 2006..

Hypoxia-induced apelin expression regulates endothelial cell proliferation and regenerative angiogenesis

Authors:
Eyries M, Siegfried G, Ciumas M, Montagne K, Agrapart M, Lebrin F, Soubrier F
Citation:
Circ Res. 2008 Aug 15;103(4):432-40. Epub 2008 Jul 10
Epub:
Not Epub
Abstract:
Apelin has been identified as the endogenous ligand of the human orphan G protein-coupled receptor APJ. This peptide exerts a...
Organism or Cell Type:
zebrafish
Citation Extract:
Eyries M, Siegfried G, Ciumas M, Montagne K, Agrapart M, Lebrin F, Soubrier F. Hypoxia-induced apelin expression regulates endothelial cell proliferation and regenerative angiogenesis. Circ Res. 2008 Aug 15;103(4):432-40. Epub 2008 Jul 10.

Incomplete splicing, cell division defects, and hematopoietic blockage in dhx8 mutant zebrafish

Authors:
English MA, Lei L, Blake T, Wincovitch SM Sr, Sood R, Azuma M, Hickstein D, Liu PP
Citation:
Dev Dyn. 2012 May;241(5):879-89. doi: 10.1002/dvdy.23774. Epub 2012 Mar 29
Epub:
Not Epub
Abstract:
BACKGROUND: Vertebrate hematopoiesis is a complex developmental process that is controlled by genes in diverse pathways. To...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
English MA, Lei L, Blake T, Wincovitch SM Sr, Sood R, Azuma M, Hickstein D, Liu PP. Incomplete splicing, cell division defects, and hematopoietic blockage in dhx8 mutant zebrafish. Dev Dyn. 2012 May;241(5):879-89. doi: 10.1002/dvdy.23774. Epub 2012 Mar 29.

Induction of revertant fibres in the mdx mouse using antisense oligonucleotides

Authors:
Fall AM, Johnsen R, Honeyman K, Iversen P, Fletcher S, Wilton SD
Citation:
Genet Vaccines Ther. 2006 May 24;4:3
Epub:
Not Epub
Abstract:
ABSTRACT: BACKGROUND: Duchenne muscular dystrophy is a fatal genetic disorder caused by dystrophin gene mutations that result...
Delivery Method:
In vitro: transfection; in vivo: intramuscular injection
Organism or Cell Type:
MDX mice
Citation Extract:
Fall AM, Johnsen R, Honeyman K, Iversen P, Fletcher S, Wilton SD. Induction of revertant fibres in the mdx mouse using antisense oligonucleotides. Genet Vaccines Ther. 2006 May 24;4:3.

Inhibition of protocadherin-alpha function results in neuronal death in the developing zebrafish

Authors:
Emond MR, Jontes JD
Citation:
Dev Biol. 2008 Sep 1;321(1):175-87. Epub 2008 Jun 16.
Epub:
Not Epub
Abstract:
The pcdhalpha/CNR gene comprises a diverse array of neuronal cell-surface proteins of the cadherin superfamily, although very...
Organism or Cell Type:
zebrafish
Citation Extract:
Emond MR, Jontes JD. Inhibition of protocadherin-alpha function results in neuronal death in the developing zebrafish. Dev Biol. 2008 Sep 1;321(1):175-87. Epub 2008 Jun 16..

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