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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Nanobiopolymer for Direct Targeting and Inhibition of EGFR Expression in Triple Negative Breast Cancer

Authors:
Inoue S, Patil R, Portilla-Arias J, Ding H, Konda B, Espinoza A, Mongayt D, Markman JL, Elramsisy A, Phillips HW, Black KL, Holler E, Ljubimova JY
Citation:
PLoS ONE. 2012;7(2):e31070. doi:10.1371/journal.pone.0031070
Epub:
Not Epub
Abstract:
Treatment options for triple negative breast cancer (TNBC) are generally limited to cytotoxic chemotherapy. Recently, anti-...
Delivery Method:
in vivo: injection
Organism or Cell Type:
Mice, tumor model
Citation Extract:
Inoue S, Patil R, Portilla-Arias J, Ding H, Konda B, Espinoza A, Mongayt D, Markman JL, Elramsisy A, Phillips HW, Black KL, Holler E, Ljubimova JY. Nanobiopolymer for Direct Targeting and Inhibition of EGFR Expression in Triple Negative Breast Cancer. PLoS ONE. 2012;7(2):e31070. doi:10.1371/journal.pone.0031070.

Polymalic Acid–Based Nanobiopolymer Provides Efficient Systemic Breast Cancer Treatment by Inhibiting both HER2/neu Receptor Synthesis and Activity

Authors:
Inoue S, Ding H, Portilla-Arias J, Hu J, Konda B, Fujita M, Espinoza A, Suhane S, Riley M, Gates M, Patil R, Penichet ML, Ljubimov AV, Black KL, Holler E, Ljubimova JY
Citation:
Cancer Res. 2011 Feb 8;71(4):1454–64 [Epub ahead of print] doi:10.1158/0008-5472.CAN-10-3093
Epub:
Not Epub
Abstract:
Biodegradable nanopolymers are believed to offer great potential in cancer therapy. Here, we report the characterization of a...
Delivery Method:
Nanoparticle
Citation Extract:
Inoue S, Ding H, Portilla-Arias J, Hu J, Konda B, Fujita M, Espinoza A, Suhane S, Riley M, Gates M, Patil R, Penichet ML, Ljubimov AV, Black KL, Holler E, Ljubimova JY. Polymalic Acid–Based Nanobiopolymer Provides Efficient Systemic Breast Cancer Treatment by Inhibiting both HER2/neu Receptor Synthesis and Activity. Cancer Res. 2011 Feb 8;71(4):1454–64 [Epub ahead of print] doi:10.1158/0008-5472.CAN-10-3093.

Protective role of Cdc48 against neurodegeneration via Ubiquitin-proteasome system dysfunction during Zebrafish development

Authors:
Imamura S, Yabu Y, Yamashita M
Citation:
J Biol Chem. 2012 Jun 29;287(27):23047-56. doi: 10.1074/jbc.M111.332882. Epub 2012 May 1.
Epub:
Not Epub
Abstract:
Cell division cycle 48 (CDC48), a ubiquitin-dependent molecular chaperone, is thought to mediate a variety of degradative and...
Organism or Cell Type:
zebrafish
Citation Extract:
Imamura S, Yabu Y, Yamashita M. Protective role of Cdc48 against neurodegeneration via Ubiquitin-proteasome system dysfunction during Zebrafish development. J Biol Chem. 2012 Jun 29;287(27):23047-56. doi: 10.1074/jbc.M111.332882. Epub 2012 May 1..

Regulatory blueprint for a chordate embryo

Authors:
Imai KS, Levine M, Satoh N, Satou Y
Citation:
Science. 2006 May 26;312(5777):1183-7
Epub:
Not Epub
Abstract:
Ciona is an emerging model system for elucidating gene networks in development. Comprehensive in situ hybridization assays have...
Organism or Cell Type:
Ciona
Citation Extract:
Imai KS, Levine M, Satoh N, Satou Y. Regulatory blueprint for a chordate embryo. Science. 2006 May 26;312(5777):1183-7.

Six3 represses nodal activity to establish early brain asymmetry in zebrafish

Authors:
Inbal A, Kim SH, Shin J, Solnica-Krezel L
Citation:
Neuron. 2007 Aug 2;55(3):407-15
Epub:
Not Epub
Abstract:
The vertebrate brain is anatomically and functionally asymmetric; however, the molecular mechanisms that establish left-right...
Organism or Cell Type:
zebrafish
Citation Extract:
Inbal A, Kim SH, Shin J, Solnica-Krezel L. Six3 represses nodal activity to establish early brain asymmetry in zebrafish. Neuron. 2007 Aug 2;55(3):407-15.

Targeted knockdown of an opsin gene inhibits the swimming behaviour photoresponse of ascidian larvae.

Authors:
Inada K, Horie T, Kusakabe T, Tsuda M.
Citation:
Neurosci Lett. 2003 Aug 28;347(3):167-70
Epub:
Not Epub
Abstract:
The sequencing of the ascidian Ciona intestinalis genome was completed at the end of 2002. Effective targeted gene knockdown in...
Delivery Method:
Microinjection
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Inada K, Horie T, Kusakabe T, Tsuda M.. Targeted knockdown of an opsin gene inhibits the swimming behaviour photoresponse of ascidian larvae.. Neurosci Lett. 2003 Aug 28;347(3):167-70.

The extracellular adenosine deaminase growth factor, ADGF/CECR1, plays a role in Xenopus embryogenesis via the adenosine/P1 receptor

Authors:
Iijima R, Kunieda T, Yamaguchi S, Kamigaki H, Fujii-Taira I, Sekimizu K, Kubo T, Natori S, Homma KJ
Citation:
J Biol Chem. 2008 Jan 25;283(4):2255-64. Epub 2007 Nov 21.
Epub:
Not Epub
Abstract:
Adenosine deaminase-related growth factors (ADGF), also known as CECR1 in vertebrates, are a novel family of growth factors...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Iijima R, Kunieda T, Yamaguchi S, Kamigaki H, Fujii-Taira I, Sekimizu K, Kubo T, Natori S, Homma KJ. The extracellular adenosine deaminase growth factor, ADGF/CECR1, plays a role in Xenopus embryogenesis via the adenosine/P1 receptor. J Biol Chem. 2008 Jan 25;283(4):2255-64. Epub 2007 Nov 21..

The homeobox genes vox and vent are redundant repressors of dorsal fates in zebrafish

Authors:
Imai Y, Gates MA, Melby AE, Kimelman D, Schier AF, Talbot WS
Citation:
Development 2001 Jun;128(12):2407-20
Epub:
Not Epub
Abstract:
Ventralizing transcriptional repressors in the Vox/Vent family have been proposed to be important regulators of dorsoventral...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Imai Y, Gates MA, Melby AE, Kimelman D, Schier AF, Talbot WS. The homeobox genes vox and vent are redundant repressors of dorsal fates in zebrafish. Development 2001 Jun;128(12):2407-20.

The homodimeric kinesin, Kif17, is essential for vertebrate photoreceptor sensory outer segment development

Authors:
Insinna C, Pathak N, Perkins B, Drummond I, Besharse JC
Citation:
Dev Biol. 2008 Apr 1;316(1):160-70. Epub 2008 Jan 31
Epub:
Not Epub
Abstract:
Sensory cilia and intraflagellar transport (IFT), a pathway essential for ciliogenesis, play important roles in embryonic...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Insinna C, Pathak N, Perkins B, Drummond I, Besharse JC. The homodimeric kinesin, Kif17, is essential for vertebrate photoreceptor sensory outer segment development. Dev Biol. 2008 Apr 1;316(1):160-70. Epub 2008 Jan 31.

The impairment of HCCS leads to MLS syndrome by activating a non-canonical cell death pathway in the brain and eyes

Authors:
Indrieri A, Conte I, Chesi G, Romano A, Quartararo J, Tatè R, Ghezzi D, Zeviani M, Goffrini P, Ferrero I, Bovolenta P, Franco B
Citation:
EMBO Mol Med. 2013 Feb;5(2):280-93. doi: 10.1002/emmm.201201739. Epub 2013 Jan 22
Epub:
Not Epub
Abstract:
Mitochondrial-dependent (intrinsic) programmed cell death (PCD) is an essential homoeostatic mechanism that selects...
Delivery Method:
Microinjection
Organism or Cell Type:
medaka
Citation Extract:
Indrieri A, Conte I, Chesi G, Romano A, Quartararo J, Tatè R, Ghezzi D, Zeviani M, Goffrini P, Ferrero I, Bovolenta P, Franco B. The impairment of HCCS leads to MLS syndrome by activating a non-canonical cell death pathway in the brain and eyes. EMBO Mol Med. 2013 Feb;5(2):280-93. doi: 10.1002/emmm.201201739. Epub 2013 Jan 22.

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