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In Vivo Monitoring of Carbonic Anhydrases Expression on Growth of Larval Zebrafish: A New Environment-Sensitive Fluorophore for Responsive Turn-On Fluorescence

Authors: 
Chou C-H, Wu C-Y, Chen C-L, Zhou J-Q, Kao Y-C, Chen H-Y, Lin P-C
Citation: 
Chem Comm. 2020;[Epub ahead pf print] doi:10.1039/D0CC03090B
Abstract: 
This study monitors dynamic progress of newly developed background-free, target responsive strategy; 2,3-dihydroquinolin-4-imine (DQI) that can instantly respond to environmental changes with fluorescence enhancement, revealing a comprehensive platform for in vivo fluorescence bioimaging of mebrane-bound carbonic anhydrase II on HeLa cells and its expression over the growth larval zebrafish.
Epub: 
Yes
Link to Publication: 
https://pubs.rsc.org/en/content/articlelanding/2020/cc/d0cc03090b
Organism or Cell Type: 
zebrafish
Delivery Method: 
microinjection