Citation:
Small. 2011 Feb 7;7(3):306-10. doi: 10.1002/smll.201001774. Epub 2010 Dec 22.
Abstract:
Highly selective DNA probes prepared by functionalizing gold nanoparticles with nonionic morpholino oligos are described. The nanoparticle probes offer enzyme-like selectivity based simply on hybridization reactions, allowing visual detection of a perfectly matched target within a large excess (>1000-fold) of single-base-mismatched DNA.