You are here

Data on the effects of N-cadherin perturbation on the expression of type II cadherin proteins and major signaling pathways

Authors: 
Rodgers C
Citation: 
Data in Brief. 2018;[Epub] doi:10.1016/j.dib.2018.08.029
Abstract: 
This article contains data related to the research article entitled, "A catenin-dependent balance between N-cadherin and E-cadherin controls neuroectodermal cell fate choices" (Rogers and Bronner, 2018) [1]. The data presented here include (1) proximity ligation assays using antibodies that recognize type I cadherins (N-cadherin and E-cadherin) co-incubated with antibodies against type II cadherins (Cadherin-6B and Cadherin-11) to test heterotypic interactions in vivo; (2) expression of Cadherin-6B and Cadherin-7 after electroporation with full length N-cadherin and N-cadherin translation-blocking morpholino; and (3) expression of WNT, Notch and TGF-β signaling reporters and effectors upon loss of N-cadherin protein in chicken embryos.
Epub: 
Yes
Organism or Cell Type: 
Gallus gallus (chick)
Delivery Method: 
injection and electroporation